sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4emw | FAD | Coenzyme A disulfide reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4emw | FAD | Coenzyme A disulfide reductase | / | 1.445 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 1.328 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 1.323 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 1.323 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 1.290 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 1.284 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 1.284 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 1.216 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 1.059 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 1.052 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 1.028 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.992 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.944 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.934 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.919 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.915 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.901 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.900 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.884 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.872 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.864 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.861 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.858 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.836 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.834 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.829 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.824 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.823 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.819 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.816 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.816 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.816 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.816 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.816 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.812 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.811 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.810 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.805 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.804 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.803 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.800 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.800 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.796 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.787 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.786 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.785 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.783 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.783 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.782 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.781 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.781 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.779 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.779 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.778 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.776 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.774 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.771 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.770 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.764 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.764 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.762 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.762 | |
| 2bac | FAD | Putative aminooxidase | / | 0.762 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.762 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.761 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.760 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.759 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.759 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.759 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.758 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.757 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.757 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.756 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.756 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.755 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.754 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.753 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.752 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.751 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.751 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.750 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.748 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.747 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.746 | |
| 4tm3 | FAD | KtzI | / | 0.745 | |
| 4x4j | FAD | Putative oxygenase | / | 0.744 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.742 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.741 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.741 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.741 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.739 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.739 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.738 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.738 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.734 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.734 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.733 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.732 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.732 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.731 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.731 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.730 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.730 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.728 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.727 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.727 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.727 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.726 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.726 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.726 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.725 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.724 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.724 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.724 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.723 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.723 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.722 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.720 | |
| 2cdu | FAD | NADH oxidase | / | 0.720 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.720 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.720 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.720 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.719 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.717 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.717 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.717 | |
| 2qa1 | FAD | PgaE | / | 0.715 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.715 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.714 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.713 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.713 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.713 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.713 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.712 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.711 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.711 | |
| 3rha | FDA | Putrescine oxidase | / | 0.710 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.709 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.709 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.709 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.708 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.708 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.707 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.707 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.706 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.706 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.705 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.705 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.704 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.704 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.704 | |
| 4k5r | FAD | Oxygenase | / | 0.704 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.704 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.703 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.702 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.701 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.700 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.700 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.700 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.699 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.698 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.698 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.698 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.697 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.697 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.697 | |
| 4h4s | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.697 | |
| 4h4y | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.697 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.697 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.696 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.694 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.694 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.694 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.694 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.693 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.693 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.693 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.693 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.692 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.692 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.692 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.692 | |
| 4nte | FAD | DepH | / | 0.692 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.691 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.691 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.689 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.689 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.689 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.688 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.688 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.688 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.687 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.687 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.685 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.685 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.685 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.685 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.684 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.683 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.683 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.683 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.683 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.682 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.682 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.682 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.681 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.681 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.679 | |
| 4ysh | FAD | Glycine oxidase | / | 0.679 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.678 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.678 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.678 | |
| 3h5n | ATP | MccB protein | / | 0.678 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.678 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.678 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.678 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.677 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.676 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.676 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.675 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.675 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.675 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.675 | |
| 3c96 | FAD | Flavin-containing monooxygenase | / | 0.674 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.674 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.674 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.673 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.673 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.673 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.672 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.672 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.672 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.672 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.672 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.671 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.671 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.671 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.670 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.670 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.669 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.669 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.669 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.669 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.669 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.668 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.668 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.667 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.667 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.667 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.666 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.666 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.666 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.665 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.664 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.664 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.664 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.663 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.663 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.663 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.663 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.663 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.662 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.662 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.661 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.661 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.661 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.660 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.660 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.660 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.660 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.659 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.659 | |
| 3g8a | SAH | Ribosomal RNA small subunit methyltransferase G | / | 0.659 | |
| 4icy | FAD | PgaE | / | 0.659 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.658 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.658 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.658 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.658 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.658 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.658 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.658 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.658 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.657 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.657 | |
| 3ge6 | FMN | Nitroreductase | / | 0.657 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.657 | |
| 4hia | FMN | LOV protein | / | 0.657 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.656 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.656 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.656 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.655 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.655 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.655 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.655 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.655 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.655 | |
| 2yxl | SFG | 450aa long hypothetical fmu protein | / | 0.655 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.655 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.655 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.655 | |
| 4hj4 | FMN | LOV protein | / | 0.655 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.655 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.654 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.654 | |
| 4yxd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.654 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.653 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.653 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.653 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.652 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.652 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.652 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.651 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.651 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.650 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.650 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.650 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.650 |