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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4lsjLSJGlucocorticoid receptor

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4lsjLSJGlucocorticoid receptor/1.000
2oaxSNLMineralocorticoid receptor/0.579
3zrbOR8Progesterone receptor/0.566
3zraORBProgesterone receptor/0.565
3zr7OR8Progesterone receptor/0.564
1e3kR18Progesterone receptor/0.561
3d90NOGProgesterone receptor/0.560
2w8y486Progesterone receptor/0.552
4a2jAS0Progesterone receptor/0.552
2w8yNDRProgesterone receptor/0.551
4apuA2KProgesterone receptor/0.547
3zrbORCProgesterone receptor/0.546
4p6wMOFGlucocorticoid receptor/0.540
2ab2SNLMineralocorticoid receptor/0.538
3vhuSNLMineralocorticoid receptor/0.538
4apuOR8Progesterone receptor/0.534
1sqnNDRProgesterone receptor/0.533
2aaxPDNMineralocorticoid receptor/0.533
2abi1CAMineralocorticoid receptor/0.532
3bqdDAYGlucocorticoid receptor/0.530
2a3iC0RMineralocorticoid receptor/0.529
1y9r1CAMineralocorticoid receptor/0.524
2aa2AS4Mineralocorticoid receptor/0.523
2aa6STRMineralocorticoid receptor/0.520
1gs4ZK5Androgen receptor/0.519
2aclREARetinoic acid receptor RXR-alpha/0.519
2amb17HAndrogen receptor/0.517
2yloTESAndrogen receptor/0.516
1ya3STRMineralocorticoid receptor/0.515
1s9qOHTEstrogen-related receptor gamma/0.509
1sr7MOFProgesterone receptor/0.508
3h3sH15Collagen type IV alpha-3-binding protein/0.508
1p93DEXGlucocorticoid receptor/0.507
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.507
2aa5STRMineralocorticoid receptor/0.506
2pklDHTAndrogen receptor/0.506
4udaDEXMineralocorticoid receptor/0.504
3h3r14HCollagen type IV alpha-3-binding protein/0.500
2aa71CAMineralocorticoid receptor/0.499
2pixDHTAndrogen receptor/0.499
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.499
1zucT98Progesterone receptor/0.498
2pivDHTAndrogen receptor/0.497
3h3t16HCollagen type IV alpha-3-binding protein/0.497
2ovmAS0Progesterone receptor/0.496
1xj7DHTAndrogen receptor/0.495
3ns2PYVAbscisic acid receptor PYL2/0.494
1xq3R18Androgen receptor/0.493
2vbpVB1Isopenicillin N synthase1.21.3.10.493
2ovhAS0Progesterone receptor/0.492
3fc6REARetinoic acid receptor RXR-alpha/0.492
2amaDHTAndrogen receptor/0.491
2pitDHTAndrogen receptor/0.491
4g1y0VOVitamin D3 receptor A/0.489
4oeaDHTAndrogen receptor/0.489
5k2cZMAAdenosine receptor A2a/0.489
1t7rDHTAndrogen receptor/0.488
1xowR18Androgen receptor/0.487
2pioDHTAndrogen receptor/0.487
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.487
1rkhVD2Vitamin D3 receptor/0.485
2qpyDHTAndrogen receptor/0.485
4ia1BIVVitamin D3 receptor A/0.485
5k2aZMAAdenosine receptor A2a/0.485
2piwDHTAndrogen receptor/0.484
3zqtTESAndrogen receptor/0.483
2hasC3OVitamin D3 receptor/0.482
2pirDHTAndrogen receptor/0.482
2piuDHTAndrogen receptor/0.482
4ohaHFTAndrogen receptor/0.482
1nhz486Glucocorticoid receptor/0.481
2bf7HBIPteridine reductase 11.5.1.330.481
2pipDHTAndrogen receptor/0.481
1fmjRTLRetinol dehydratase/0.480
2ao6R18Androgen receptor/0.480
2hb7O1CVitamin D3 receptor/0.480
2z4jDHTAndrogen receptor/0.480
4g1z0VPVitamin D3 receptor A/0.480
1txiTX5Vitamin D3 receptor/0.479
2o4rVD5Vitamin D3 receptor/0.479
2po7CHDFerrochelatase, mitochondrial4.99.1.10.478
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.478
2g44T3OEstrogen receptor/0.476
3nj0PYVAbscisic acid receptor PYL2/0.476
3vg9ZMAAdenosine receptor A2a/0.476
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.475
2j7yE3OEstrogen receptor beta/0.475
3mneDEXGlucocorticoid receptor/0.475
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.474
4udcDEXGlucocorticoid receptor/0.474
3sn6P0GBeta-2 adrenergic receptor/0.474
3w0hW12Vitamin D3 receptor/0.473
2rqfJH3Hemolymph juvenile hormone binding protein/0.472
2zlaVDBVitamin D3 receptor/0.472
3gwfFADCyclohexanone monooxygenase/0.472
1blzACVIsopenicillin N synthase1.21.3.10.471
1jpaANPEphrin type-B receptor 22.7.10.10.471
2bu9HFVIsopenicillin N synthase1.21.3.10.471
2zlcVDXVitamin D3 receptor/0.471
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
1qknRALEstrogen receptor beta/0.470
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.470
2g1n1IGRenin3.4.23.150.470
2wo7ASVIsopenicillin N synthase1.21.3.10.470
4dbzNDPPutative ketoacyl reductase1.3.10.470
1t73DHTAndrogen receptor/0.469
2fai459Estrogen receptor/0.469
2vbdV10Isopenicillin N synthase1.21.3.10.469
2ylqTESAndrogen receptor/0.469
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
4ap1NAPSteroid monooxygenase/0.469
4ugaH4BNitric oxide synthase oxygenase1.14.13.1650.469
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.469
1kqwRTLCellular retinol-binding protein type II/0.468
1t65DHTAndrogen receptor/0.468
4l8u9AZSerum albumin/0.468
1e3gR18Androgen receptor/0.467
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
2p15EZTEstrogen receptor/0.467
2q7lTESAndrogen receptor/0.467
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
3lanKBTGag-Pol polyprotein2.7.7.490.467
3mdmFJZCholesterol 24-hydroxylase/0.467
3qm4PN0Cytochrome P450 2D6/0.467
3vrwYS5Vitamin D3 receptor/0.467
4j6cSTRCytochrome P450 monooxygenase/0.467
1ia2TQ4Dihydrofolate reductase1.5.1.30.466
2y6fM9FIsopenicillin N synthase1.21.3.10.466
3vruYS3Vitamin D3 receptor/0.466
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.466
1bk0ACVIsopenicillin N synthase1.21.3.10.465
1m2zDEXGlucocorticoid receptor/0.465
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.465
3kpzZNEVitamin D3 receptor/0.465
3s7a684Dihydrofolate reductase1.5.1.30.465
4lsl1YQGag-Pol polyprotein2.7.7.490.465
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1w06W05Isopenicillin N synthase1.21.3.10.464
2yhdTESAndrogen receptor/0.464
3a783EVVitamin D3 receptor/0.464
3mnpDEXGlucocorticoid receptor/0.464
3ollESTEstrogen receptor beta/0.464
3w5rLOAVitamin D3 receptor/0.464
4ofuDHTAndrogen receptor/0.464
1errRALEstrogen receptor/0.463
1s19MC9Vitamin D3 receptor/0.463
1t79DHTAndrogen receptor/0.463
1uhlMEIRetinoic acid receptor RXR-beta/0.463
1upw444Oxysterols receptor LXR-beta/0.463
1zky689Estrogen receptor/0.463
2bxqIMNSerum albumin/0.463
2fpcSCGStrictosidine synthase4.3.3.20.463
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.463
3up0D7SaceDAF-12/0.463
3vt65YIVitamin D3 receptor/0.463
3w5p4OAVitamin D3 receptor/0.463
4p6xHCYGlucocorticoid receptor/0.463
2q7iTESAndrogen receptor/0.462
3d75NBBPheromone-binding protein ASP1/0.462
3k47D09Dihydrofolate reductase1.5.1.30.462
3v1s0LHStrictosidine synthase4.3.3.20.462
3w5tLHPVitamin D3 receptor/0.462
3zkyWT4Isopenicillin N synthase1.21.3.10.462
4i8vBHFCytochrome P450 1A11.14.14.10.462
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.462
1jtqLY3Thymidylate synthase/0.461
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.461
1kzjCB3Thymidylate synthase/0.460
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.460
3vtcTK3Vitamin D3 receptor/0.460
3zkuHCVIsopenicillin N synthase1.21.3.10.460
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.460
4k6i9RARetinoic acid receptor RXR-alpha/0.460
4q0a4OAVitamin D3 receptor A/0.460
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.459
1k749CRRetinoic acid receptor RXR-alpha/0.459
1m9k7NINitric oxide synthase, endothelial1.14.13.390.459
1obnASVIsopenicillin N synthase1.21.3.10.459
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
2y60M8FIsopenicillin N synthase1.21.3.10.459
2zbaZBATrichothecene 3-O-acetyltransferase/0.459
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4o1mNADEnoyl-acyl carrier reductase/0.459
4ofrDHTAndrogen receptor/0.459
1kkq471Peroxisome proliferator-activated receptor alpha/0.458
1oc1ASVIsopenicillin N synthase1.21.3.10.458
1vrwNAIEnoyl-ACP reductase/0.458
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2bbqPFGThymidylate synthase/0.458
2yatEEUEstrogen receptor/0.458
3dolGWIPol protein/0.458
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.458
3vt3VDXVitamin D3 receptor/0.458
4m2xTMQDihydrofolate reductase1.5.1.30.458
1fmlRTLRetinol dehydratase/0.457
1hb1OCVIsopenicillin N synthase1.21.3.10.457
1kl2FONSerine hydroxymethyltransferase/0.457
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.457
1uzwCDHIsopenicillin N synthase1.21.3.10.457
1xlsREARetinoic acid receptor RXR-alpha/0.457
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2cppCAMCamphor 5-monooxygenase1.14.15.10.457
3dr1C5DVitamin D3 receptor A/0.457
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4bj9UHBTankyrase-22.4.2.300.457
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
1ia3TQ5Dihydrofolate reductase1.5.1.30.456
1kmvLIIDihydrofolate reductase1.5.1.30.456
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
2dhfDZFDihydrofolate reductase1.5.1.30.456
2jb4A14Isopenicillin N synthase1.21.3.10.456
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.456
3oafOAGDihydrofolate reductase1.5.1.30.456
4oeyDHTAndrogen receptor/0.456
4rujVDXVitamin D3 receptor A/0.456
4xe606UDihydrofolate reductase1.5.1.30.456
1b2lNDCAlcohol dehydrogenase1.1.1.10.455
1klkPMDDihydrofolate reductase1.5.1.30.455
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
2iviACWIsopenicillin N synthase1.21.3.10.455
2piqDHTAndrogen receptor/0.455
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.455
3maaFKPAdenylate cyclase type 2/0.455
3maaFKPAdenylate cyclase type 5/0.455
3own3OWRenin3.4.23.150.455
3p84FMNPentaerythritol tetranitrate reductase/0.455
3vucHHERenin3.4.23.150.455
3zoiM2WIsopenicillin N synthase1.21.3.10.455
4dscA8SAbscisic acid receptor PYL3/0.455
4ia7BIVVitamin D3 receptor A/0.455
4iteTEYVitamin D3 receptor/0.455
1aiqCB3Thymidylate synthase/0.454
1dduCB3Thymidylate synthase/0.454
1g3mPCQEstrogen sulfotransferase2.8.2.40.454
1s3uTQDDihydrofolate reductase1.5.1.30.454
2j0m4STFocal adhesion kinase 12.7.10.20.454
2o4jVD4Vitamin D3 receptor/0.454
2zl9VDAVitamin D3 receptor/0.454
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3fhxPLPPyridoxal kinase2.7.1.350.454
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
3vt5YI2Vitamin D3 receptor/0.454
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4ivy1GTEstrogen receptor/0.454
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.454
1dtpAPUDiphtheria toxin/0.453
1ie9VDXVitamin D3 receptor/0.453
1ppjANYCytochrome b/0.453
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.453
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3mnoDEXGlucocorticoid receptor/0.453
3nxyD2HDihydrofolate reductase1.5.1.30.453
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.453
3vt7VDXVitamin D3 receptor/0.453
4e0u0MVCyclic dipeptide N-prenyltransferase/0.453
4g20484Vitamin D3 receptor A/0.453
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.453
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.453
4oedDHTAndrogen receptor/0.453
4oghHFTAndrogen receptor/0.453
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.453
1rk3VDXVitamin D3 receptor/0.452
1s9pDESEstrogen-related receptor gamma/0.452
2ociTYCValacyclovir hydrolase3.10.452
2uxoTACHTH-type transcriptional regulator TtgR/0.452
3djfBC3Purine nucleoside phosphorylase/0.452
3fznD7KBenzoylformate decarboxylase4.1.1.70.452
3pl8FADPyranose 2-oxidase/0.452
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.452
3repATPIntegrin-linked protein kinase2.7.11.10.452
3rr3FLRProstaglandin G/H synthase 21.14.99.10.452
3up3XCAaceDAF-12/0.452
4a9e3PFBromodomain-containing protein 2/0.452
4esoNAPPutative oxidoreductase/0.452
4g1d0VKVitamin D3 receptor A/0.452
4hlwTESAndrogen receptor/0.452
4jlj1NMDeoxycytidine kinase2.7.1.740.452
4l5b1UXDeoxycytidine kinase2.7.1.740.452
1jutLYDThymidylate synthase/0.451
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.451
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
3ipq965Oxysterols receptor LXR-alpha/0.451
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.451
3wfgWFGMineralocorticoid receptor/0.451
4g95OAGDihydrofolate reductase1.5.1.30.451
4i1nFOLDihydrofolate reductase1.5.1.30.451
4iv41GSEstrogen receptor/0.451
4jhiEMUNodulin-13/0.451
4oezDHTAndrogen receptor/0.451
4oilHFTAndrogen receptor/0.451
1rx7FOLDihydrofolate reductase1.5.1.30.450
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
2q7kTESAndrogen receptor/0.450
2q9fC3SCholesterol 24-hydroxylase/0.450
2vcmM11Isopenicillin N synthase1.21.3.10.450
2vdvSAMtRNA (guanine-N(7)-)-methyltransferase/0.450
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.450
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3koo24DBifunctional epoxide hydrolase 23.3.2.100.450
3nefPYVAbscisic acid receptor PYL1/0.450
3pm0BHFCytochrome P450 1B1/0.450
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.450
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.450
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.450
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.450
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
4h9506UDihydrofolate reductase1.5.1.30.450
4ia2BIVVitamin D3 receptor A/0.450
4pkwGM6Lethal factor3.4.24.830.450
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.450
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.449
2dw4FADLysine-specific histone demethylase 1A10.449
2hamC33Vitamin D3 receptor/0.449
2harOCCVitamin D3 receptor/0.449
3h3qH13Collagen type IV alpha-3-binding protein/0.449
3o8tBMUMitogen-activated protein kinase 14/0.449
3p9tTCLRepressor/0.449
3vtbTKAVitamin D3 receptor/0.449
3wecAUICytochrome P450/0.449
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4fhf0TTSpore photoproduct lyase/0.449
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4j24ESTEstrogen receptor beta/0.449
4wa9AXITyrosine-protein kinase ABL12.7.10.20.449
1cjkFOKAdenylate cyclase type 2/0.448
1cjkFOKAdenylate cyclase type 5/0.448
1fbyREARetinoic acid receptor RXR-alpha/0.448
1phgMYTCamphor 5-monooxygenase1.14.15.10.448
1rd7FOLDihydrofolate reductase1.5.1.30.448
1t5zDHTAndrogen receptor/0.448
1x8lOXRRetinol dehydratase/0.448
2cjfRP43-dehydroquinate dehydratase4.2.1.100.448
2dvlFADAcyl-CoA dehydrogenase/0.448
2hkoFADLysine-specific histone demethylase 1A10.448
2on6IMHPurine nucleoside phosphorylase2.4.2.10.448
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.448
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3fwjCAMCamphor 5-monooxygenase1.14.15.10.448
3hl0NADMaleylacetate reductase/0.448
3p8jFMNPentaerythritol tetranitrate reductase/0.448
4g210VPVitamin D3 receptor A/0.448
4g2gTDHMycocyclosin synthase1.14.21.90.448
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4mlhVO2Glucokinase2.7.1.20.448
4qa0SHHHistone deacetylase 83.5.1.980.448
1hb3SCVIsopenicillin N synthase1.21.3.10.447
1iwjCAMCamphor 5-monooxygenase1.14.15.10.447
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.447
1t63DHTAndrogen receptor/0.447
2q5oPPYIndole-3-pyruvate decarboxylase4.1.1.740.447
2yg4FADPutrescine oxidase/0.447
3dds26BGlycogen phosphorylase, liver form2.4.1.10.447
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.447
3lakKR1Gag-Pol polyprotein2.7.7.490.447
3qlrNDPDihydrofolate reductase1.5.1.30.447
3qly55VUncharacterized protein/0.447
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.447
4a8v2ANMajor pollen allergen Bet v 1-J/0.447
4bfvZVVPantothenate kinase2.7.1.330.447
4fvz4KJNitric oxide synthase, brain1.14.13.390.447
4j6dTESCytochrome P450 monooxygenase/0.447
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.447
5eccNAPDehydrofolate reductase type I/0.447
1culFOKAdenylate cyclase type 2/0.446
1culFOKAdenylate cyclase type 5/0.446
1g50ESTEstrogen receptor/0.446
2jedLG8Protein kinase C theta type2.7.11.130.446
2jn3JN3Fatty acid-binding protein, liver/0.446
2m56CAMCamphor 5-monooxygenase1.14.15.10.446
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3d84NDPDihydrofolate reductase1.5.1.30.446
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.446
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4boeCLRJapanin/0.446
4klrCHDFerrochelatase, mitochondrial4.99.1.10.446
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.446
4y8wSTRSteroid 21-hydroxylase/0.446
1rx1NAPDihydrofolate reductase1.5.1.30.445
1rx8FOLDihydrofolate reductase1.5.1.30.445
2gjlFMNNitronate monooxygenase1.13.12.160.445
2p1v5TNRetinoic acid receptor RXR-alpha/0.445
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.445
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3i6iNDPPutative leucoanthocyanidin reductase 1/0.445
3pd4A3GThreonine--tRNA ligase6.1.1.30.445
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.445
3vyfVYFRenin3.4.23.150.445
4fw05KJNitric oxide synthase, brain1.14.13.390.445
4i22IREEpidermal growth factor receptor2.7.10.10.445
4ia3BIVVitamin D3 receptor A/0.445
4ise1FWGlucokinase2.7.1.20.445
4jlk1NODeoxycytidine kinase2.7.1.740.445
4rrrA3TThreonine--tRNA ligase6.1.1.30.445
5jlaNADPutative short-chain dehydrogenase/reductase/0.445
3emlZMAAdenosine receptor A2a/0.445
1axwMTXThymidylate synthase/0.444
1bim0QBRenin3.4.23.150.444
1mvcBM6Retinoic acid receptor RXR-alpha/0.444
1phePIYCamphor 5-monooxygenase1.14.15.10.444
2hb8MVDVitamin D3 receptor/0.444
2om9AJAPeroxisome proliferator-activated receptor gamma/0.444
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.444
2pnuENMAndrogen receptor/0.444
2q7gCCLPyrrolysine--tRNA ligase/0.444
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.444
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3h0a9RARetinoic acid receptor RXR-alpha/0.444
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.444
3uvvREARetinoic acid receptor RXR-alpha/0.444
3vrvYSDVitamin D3 receptor/0.444
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.444
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.444
5h8tRTLRetinol-binding protein 1/0.444
1db1VDXVitamin D3 receptor/0.443
1rkgVD1Vitamin D3 receptor/0.443
1s0zEB1Vitamin D3 receptor/0.443
1t7fDHTAndrogen receptor/0.443
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.443
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.443
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.443
2q66ATPPoly(A) polymerase2.7.7.190.443
2wcgMT5Glucosylceramidase3.2.1.450.443
2ykeYKEHeat shock protein HSP 90-alpha/0.443
3b9lAZZSerum albumin/0.443
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.443
3dmjGWEPol protein/0.443
3jwm5WBDihydrofolate reductase/0.443
3nr4PYVAbscisic acid receptor PYL2/0.443
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.443
4cdmFO1Deoxyribodipyrimidine photolyase/0.443
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
4pnmNU1Tankyrase-22.4.2.300.443
4uqsINENitric oxide synthase oxygenase1.14.13.1650.443
5kf1ACOPredicted acetyltransferase/0.443
5jtbZMAAdenosine receptor A2a/0.443
1m79MQ1Dihydrofolate reductase1.5.1.30.442
1pkfEPDEpothilone C/D epoxidase1.140.442
2hc4VDXVitamin D3 receptor A/0.442
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
2wkmPFYHepatocyte growth factor receptor2.7.10.10.442
3fwiCAMCamphor 5-monooxygenase1.14.15.10.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
3uudESTEstrogen receptor/0.442
3vt8YI3Vitamin D3 receptor/0.442
4ejgNCTCytochrome P450 2A131.14.14.10.442
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.442
4fxfATPPyruvate kinase PKM2.7.1.400.442
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.442
4iarERM5-hydroxytryptamine receptor 1B/0.442
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4o7uTHFThymidylate synthase/0.442
4ruoBIVVitamin D3 receptor A/0.442
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5cc9DDFDihydrofolate reductase1.5.1.30.442
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.441
1qiqACCIsopenicillin N synthase1.21.3.10.441
1r9oFLPCytochrome P450 2C9/0.441
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
1uyePU9Heat shock protein HSP 90-alpha/0.441
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.441
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.441
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2cleF6FTryptophan synthase alpha chain/0.441
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2rhrEMOPutative ketoacyl reductase1.3.10.441
2xviFADPutative flavin-containing monooxygenase/0.441
3d74NBBPheromone-binding protein ASP1/0.441
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3ghvGHCDihydrofolate reductase1.5.1.30.441
3h1vTK1Glucokinase2.7.1.20.441
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3l034OHEstrogen receptor/0.441
3nmpPYVAbscisic acid receptor PYL2/0.441
3s79ASDAromatase1.14.14.140.441
3vt9YI4Vitamin D3 receptor/0.441
3w0yDS4Vitamin D3 receptor/0.441
4bb3KKAIsopenicillin N synthase1.21.3.10.441
4c02TAKActivin receptor type-12.7.11.300.441
4c9pCAMCytochrome P450/0.441
4itfTFYVitamin D3 receptor/0.441
4qa2SHHHistone deacetylase 83.5.1.980.441
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.441
1cs4FOKAdenylate cyclase type 2/0.440
1cs4FOKAdenylate cyclase type 5/0.440
1dhiMTXDihydrofolate reductase1.5.1.30.440
1dhjMTXDihydrofolate reductase1.5.1.30.440
1dr3HBIDihydrofolate reductase1.5.1.30.440
1fkoEFZGag-Pol polyprotein2.7.7.490.440
1og5SWFCytochrome P450 2C9/0.440
2dv7SAHDiphthine synthase/0.440
2ea2F77Methionine aminopeptidase 2/0.440
2hcdBIVVitamin D3 receptor A/0.440
2xlsFADPutative flavin-containing monooxygenase/0.440
2xvw9NRSerum albumin/0.440
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3lqfNADGalactitol dehydrogenase/0.440
3mdvCL6Cholesterol 24-hydroxylase/0.440
3njoPYVAbscisic acid receptor PYR1/0.440
3pghFLPProstaglandin G/H synthase 21.14.99.10.440
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
4c3yANB3-ketosteroid dehydrogenase/0.440
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4iv21GREstrogen receptor/0.440
4jshH4BNitric oxide synthase, brain1.14.13.390.440
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
4mr61K0Bromodomain-containing protein 2/0.440