sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.896 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.882 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.881 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.873 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.873 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.871 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.863 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.860 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.857 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.855 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.831 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.829 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.820 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.814 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.805 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.799 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.790 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.782 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.781 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.774 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.772 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.771 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.771 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.764 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.764 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.757 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.731 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.722 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.604 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.591 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.568 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.559 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.549 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.549 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.538 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.538 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.538 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.534 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.528 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.522 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.516 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.516 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.515 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.510 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.509 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.505 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.498 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.495 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.485 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.481 | |
| 4iae | 1DX | Alr2278 protein | / | 0.481 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.480 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.477 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.477 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.476 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.474 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.472 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.472 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.471 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.467 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.467 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.467 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.466 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.465 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.465 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.465 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.465 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.465 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 4rel | KMP | Glycosyltransferase | / | 0.464 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.461 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.461 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.461 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.461 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.460 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.460 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.460 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.460 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.460 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.460 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.460 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.460 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.459 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.459 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.458 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.458 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.458 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.458 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 4iah | 1DX | Alr2278 protein | / | 0.457 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.456 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.456 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.456 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.456 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.456 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.455 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.455 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.455 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.455 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.454 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.454 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.454 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.454 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.454 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.454 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.453 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.452 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.452 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 4jic | FMN | GTN Reductase | / | 0.452 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.451 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.451 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.451 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.451 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.451 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.451 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.450 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.450 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.449 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2y66 | N04 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.448 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.448 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.448 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.448 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.447 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.447 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.447 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.447 | |
| 3v2u | ATP | Protein GAL3 | / | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.447 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.447 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.446 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.445 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.445 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.445 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.445 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.444 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4o7u | THF | Thymidylate synthase | / | 0.444 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.443 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.443 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.443 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.442 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.442 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3e6e | DCS | Alanine racemase | / | 0.442 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.442 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.441 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.441 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.441 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.441 | |
| 3zrc | L8B | Von Hippel-Lindau disease tumor suppressor | / | 0.441 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.441 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.440 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.440 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3c1o | NAP | Eugenol synthase | / | 0.440 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.440 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |