sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3b28 | B2X | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.744 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.651 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.630 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.612 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.611 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.606 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.597 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.595 | |
| 1u0z | RDC | Endoplasmin | / | 0.594 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.594 | |
| 1qy5 | NEC | Endoplasmin | / | 0.589 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.589 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.584 | |
| 1ysz | NEC | Endoplasmin | / | 0.583 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.579 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.571 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.570 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.566 | |
| 1qy8 | RDI | Endoplasmin | / | 0.566 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.565 | |
| 2fyp | RDE | Endoplasmin | / | 0.561 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.556 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.554 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.550 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.549 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.547 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 1u0y | PA7 | Endoplasmin | / | 0.543 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.540 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.538 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.536 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.533 | |
| 2gfd | RDA | Endoplasmin | / | 0.533 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.529 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 2hg1 | N5O | Endoplasmin | / | 0.525 | |
| 2gqp | PA7 | Endoplasmin | / | 0.521 | |
| 2hch | N5A | Endoplasmin | / | 0.521 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 3ied | AN2 | HSP90 | / | 0.520 | |
| 1u2o | NEC | Endoplasmin | / | 0.518 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.515 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.511 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.507 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.506 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.506 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.505 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.504 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.504 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.503 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.501 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.499 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.493 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.492 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.490 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.489 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.485 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.483 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.481 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.479 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.478 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.468 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.468 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.467 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.466 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.465 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.465 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.465 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.463 | |
| 2o1u | ANP | Endoplasmin | / | 0.463 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.463 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.462 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.461 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.461 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.460 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.460 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.458 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.457 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.456 | |
| 3a6r | FMN | FMN-binding protein | / | 0.456 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.456 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.455 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.454 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.454 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.453 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.452 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4die | C5P | Cytidylate kinase | / | 0.452 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.452 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.451 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.451 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2exl | GDM | Endoplasmin | / | 0.450 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3bva | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 3so9 | 017 | Pol protein | / | 0.450 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.450 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.449 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.449 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.448 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.448 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.448 | |
| 3a20 | FMN | FMN-binding protein | / | 0.448 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.448 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.447 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.447 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.446 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.446 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.446 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.446 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.446 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.446 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.446 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.445 | |
| 1vce | SAH | Diphthine synthase | / | 0.445 | |
| 1yt0 | ADP | Endoplasmin | / | 0.445 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.445 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.445 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.445 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2e07 | SAH | Diphthine synthase | / | 0.444 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.444 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.444 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.444 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.444 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.444 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.444 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 1a8g | 2Z4 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1ohh | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1ohh | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.443 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.443 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.443 | |
| 2emr | SAH | Diphthine synthase | / | 0.443 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.443 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.442 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.442 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.442 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.441 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.441 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2nmy | ROC | Protease | / | 0.441 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.441 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.441 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.440 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.440 | |
| 2q8i | RDC | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | 2.7.11.2 | 0.440 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.440 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.440 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.440 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |