sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3am3 | TCL | Enoyl-ACP reductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3am3 | TCL | Enoyl-ACP reductase | / | 1.000 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.773 | |
| 4ige | CHJ | Enoyl-acyl carrier reductase | / | 0.705 | |
| 3lt1 | FT2 | Enoyl-ACP reductase | / | 0.695 | |
| 3lt0 | FT1 | Enoyl-ACP reductase | / | 0.670 | |
| 3lsy | FT0 | Enoyl-ACP reductase | / | 0.662 | |
| 3am4 | FT1 | Enoyl-ACP reductase | / | 0.634 | |
| 2foi | JPA | Enoyl-acyl carrier reductase | / | 0.613 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.604 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.597 | |
| 1nhg | TCL | Enoyl-ACP reductase | / | 0.591 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.589 | |
| 1nhw | TCC | Enoyl-ACP reductase | / | 0.584 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.583 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.577 | |
| 2op0 | 7PC | Enoyl-ACP reductase | / | 0.575 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.574 | |
| 1zxl | JP1 | Enoyl-ACP reductase | / | 0.571 | |
| 1nnu | TCT | Enoyl-ACP reductase | / | 0.566 | |
| 3am5 | TCL | Enoyl-ACP reductase | / | 0.561 | |
| 5coq | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.546 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.539 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.515 | |
| 3nrc | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.510 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.503 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.499 | |
| 3nj8 | NJ8 | Enoyl-acyl carrier reductase | / | 0.489 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.487 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.485 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.483 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.481 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.480 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.478 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.477 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.475 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.475 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.475 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.472 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.472 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.471 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 3fne | 8PC | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.470 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.469 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.468 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.468 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.467 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.467 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.467 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.467 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.467 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.466 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.466 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.465 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.465 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.464 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.464 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.464 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.463 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.463 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.462 | |
| 4egn | TWO | Cytochrome P450 | / | 0.462 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.462 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.462 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.461 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.461 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.460 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.460 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.460 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.460 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.459 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.458 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.458 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.458 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.457 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.457 | |
| 4l8u | 9AZ | Serum albumin | / | 0.457 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.456 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.456 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.456 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.456 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.455 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 4nvk | 2NY | Peroxidase | / | 0.455 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.455 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.455 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.454 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.454 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.454 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.454 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.453 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.453 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.453 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.453 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.452 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.452 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.452 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.452 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.452 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.452 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.451 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.451 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.451 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.451 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.451 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.450 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 3e8x | NAP | BH1520 protein | / | 0.450 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.450 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.450 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1mep | BTN | Streptavidin | / | 0.449 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.449 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.449 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.449 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 4ys2 | 2BA | Uncharacterized protein | / | 0.449 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.448 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.448 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.448 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.448 | |
| 3il5 | B82 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.448 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.448 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.448 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.448 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.448 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.447 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.447 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.447 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.447 | |
| 4lb2 | DM5 | Serum albumin | / | 0.447 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.446 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.446 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.446 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4oxi | GAP | Enterobactin synthetase component F-related protein | / | 0.446 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.446 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.445 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.445 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.445 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.445 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.445 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.444 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2ako | ADP | Glutamate 5-kinase | / | 0.444 | |
| 2ji6 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.444 | |
| 4c3s | NAD | Aldehyde Dehydrogenase | / | 0.444 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1iy8 | NAD | Levodione reductase | / | 0.443 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.443 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.443 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.443 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.443 | |
| 1axw | MTX | Thymidylate synthase | / | 0.442 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.442 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.442 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.442 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.442 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.442 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.442 | |
| 4k4f | K4F | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.441 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.441 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.441 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.441 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.441 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.440 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.440 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.440 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.440 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.440 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.440 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.440 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.440 | |
| 3nf7 | CIW | Gag-Pol polyprotein | / | 0.440 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.440 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 |