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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.11.000
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.731
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.647
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.647
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.633
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.631
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.626
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.626
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.623
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.622
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.621
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.620
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.616
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.615
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.613
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.608
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.606
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.602
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.600
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.599
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.592
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.592
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.590
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.589
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.587
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.582
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.581
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.579
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.577
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.577
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.575
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.573
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.569
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.568
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.566
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.566
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.563
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.563
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.561
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.556
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.555
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.552
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.550
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.549
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.545
3umw596Serine/threonine-protein kinase pim-12.7.11.10.544
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.541
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.534
3iw4LW4Protein kinase C alpha type2.7.11.130.534
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.534
4dymIYZActivin receptor type-12.7.11.300.531
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.529
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.526
4bgg844Activin receptor type-12.7.11.300.526
2jedLG8Protein kinase C theta type2.7.11.130.516
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
4othDRNSerine/threonine-protein kinase N1/0.514
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.513
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.510
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.510
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.506
5av2KMPDeath-associated protein kinase 12.7.11.10.506
1xjdSTUProtein kinase C theta type2.7.11.130.503
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.503
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.501
4i22IREEpidermal growth factor receptor2.7.10.10.498
3mtfA3FActivin receptor type-12.7.11.300.497
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
1wvxBD4Death-associated protein kinase 12.7.11.10.494
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.493
4grb0XGCasein kinase II subunit alpha2.7.11.10.493
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.492
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.491
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.489
4hni16WCasein kinase I isoform epsilon2.7.11.10.489
2ckeIQUDeath-associated protein kinase 2/0.488
3oom507Activin receptor type-12.7.11.300.488
4dgnLU2Casein kinase II subunit alpha2.7.11.10.488
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.487
1oiyN41Cyclin-dependent kinase 22.7.11.220.486
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.486
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.486
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.485
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.484
3u4uLNHCasein kinase II subunit alpha2.7.11.10.484
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
4c02TAKActivin receptor type-12.7.11.300.483
3a4pDFQHepatocyte growth factor receptor2.7.10.10.482
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.482
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.482
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.481
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.481
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.481
4bchT7ZCyclin-dependent kinase 92.7.11.220.481
4gg70J8Hepatocyte growth factor receptor2.7.10.10.481
4gmy0X5Tyrosine-protein kinase JAK2/0.481
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.480
2pvnP63Casein kinase II subunit alpha2.7.11.10.480
1pkdUCNCyclin-dependent kinase 22.7.11.220.479
3mvl38PMitogen-activated protein kinase 14/0.479
3q9xEMOCasein kinase II subunit alpha2.7.11.10.479
4riyADPEpidermal growth factor receptor2.7.10.10.479
4wboANWRhodopsin kinase/0.479
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.478
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.478
3ormAGSSerine/threonine protein kinase/0.478
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.478
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.478
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.478
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.478
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.477
1q1rFADPutidaredoxin reductase1.18.1.50.476
1yvj4STTyrosine-protein kinase JAK32.7.10.20.476
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.476
3gubGUBDeath-associated protein kinase 12.7.11.10.476
2j0k4STFocal adhesion kinase 12.7.10.20.475
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.475
3vf9477Tyrosine-protein kinase SYK2.7.10.20.475
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.475
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.475
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.475
1eh4IC1Casein kinase I homolog 12.7.11.10.474
1oi9N20Cyclin-dependent kinase 22.7.11.220.474
3adaNADSubunit alpha of sarocosine oxidase/0.474
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.474
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.474
2xikJ60Serine/threonine-protein kinase 252.7.11.10.473
3be9P04Casein kinase II subunit alpha2.7.11.10.473
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.473
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.473
3vt7VDXVitamin D3 receptor/0.473
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.473
1aq1STUCyclin-dependent kinase 22.7.11.220.472
1h1s4SPCyclin-dependent kinase 22.7.11.220.472
2wihP48Cyclin-dependent kinase 22.7.11.220.472
4qmySTUSerine/threonine-protein kinase 242.7.11.10.472
2itpAEEEpidermal growth factor receptor2.7.10.10.471
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.471
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.471
4g170VNCasein kinase I isoform gamma-32.7.11.10.471
4qmzB49Serine/threonine-protein kinase 242.7.11.10.471
4yuqKS1Calmodulin-like domain protein kinase/0.471
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.470
3pe2E1BCasein kinase II subunit alpha2.7.11.10.470
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.470
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.470
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.470
5auwQUEDeath-associated protein kinase 12.7.11.10.470
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.469
1ywrLI9Mitogen-activated protein kinase 14/0.469
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.469
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.469
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4dgo0JWCasein kinase II subunit alpha2.7.11.10.469
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.468
2hog710Serine/threonine-protein kinase Chk12.7.11.10.468
3bqr4RBDeath-associated protein kinase 3/0.468
3du8553Glycogen synthase kinase-3 beta2.7.11.260.468
3vt8YI3Vitamin D3 receptor/0.468
4bbe3O4Tyrosine-protein kinase JAK2/0.468
4c4h7RODual specificity protein kinase TTK2.7.12.10.468
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.468
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.468
4kbk1QGCasein kinase I isoform delta2.7.11.10.468
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.467
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.467
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.467
3uyt0CKCasein kinase I isoform delta2.7.11.10.467
4fob0USALK tyrosine kinase receptor2.7.10.10.467
1zys199Serine/threonine-protein kinase Chk12.7.11.10.466
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.466
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.466
2i0ePDSProtein kinase C beta type2.7.11.130.466
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.466
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.466
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.466
4iaq2GM5-hydroxytryptamine receptor 1B/0.466
2y4mGDXUncharacterized protein/0.465
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.464
2x1nX1NCyclin-dependent kinase 22.7.11.220.464
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.464
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.464
4jr3KJREpidermal growth factor receptor2.7.10.10.464
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.464
4wa9AXITyrosine-protein kinase ABL12.7.10.20.464
2ittAEEEpidermal growth factor receptor2.7.10.10.463
2izrBRKCasein kinase I isoform gamma-32.7.11.10.463
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.463
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.463
4c4jX21Dual specificity protein kinase TTK2.7.12.10.463
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.463
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
5auvAGIDeath-associated protein kinase 12.7.11.10.463
5auxKMPDeath-associated protein kinase 12.7.11.10.463
1bygSTUTyrosine-protein kinase CSK/0.462
1k7fIAVTryptophan synthase alpha chain/0.462
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.462
3b7dCNIGlutamate receptor 2/0.462
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.462
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.462
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.462
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.462
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
5bmvVLBTubulin alpha-1B chain/0.461
5bmvVLBTubulin beta chain/0.461
2csnCKICasein kinase I homolog 12.7.11.10.460
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.460
2h96893Mitogen-activated protein kinase 82.7.11.240.460
2zjwREFCasein kinase II subunit alpha2.7.11.10.460
3zh8C58Protein kinase C iota type2.7.11.130.460
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1lp4ANPCasein kinase II subunit alpha2.7.11.10.459
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.459
2itqITQEpidermal growth factor receptor2.7.10.10.459
2iw84SPCyclin-dependent kinase 22.7.11.220.459
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.459
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.459
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.459
4ez50RSCyclin-dependent kinase 62.7.11.220.459
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.459
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.458
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.458
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.458
2etm7PYFocal adhesion kinase 12.7.10.20.458
2q9fC3SCholesterol 24-hydroxylase/0.458
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.458
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.458
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.458
4gg50J3Hepatocyte growth factor receptor2.7.10.10.458
4hvi19STyrosine-protein kinase JAK32.7.10.20.458
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
1qxlFR8Adenosine deaminase3.5.4.40.457
2izsBRQCasein kinase I isoform gamma-32.7.11.10.457
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.457
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4anmWULCasein kinase II subunit alpha2.7.11.10.457
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.457
4fyn0VETyrosine-protein kinase SYK2.7.10.20.457
4ib4ERM5-hydroxytryptamine receptor 2B/0.457
4jia1K3Tyrosine-protein kinase JAK2/0.457
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.456
2znq401Peroxisome proliferator-activated receptor delta/0.456
4e730NRMitogen-activated protein kinase 82.7.11.240.456
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.456
4iarERM5-hydroxytryptamine receptor 1B/0.456
5cvhADPCasein kinase II subunit alpha2.7.11.10.456
5fm7ADPRuvB-like helicase/0.456
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.455
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.455
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.455
3at4CCKCasein kinase II subunit alpha2.7.11.10.455
3gc9B45Mitogen-activated protein kinase 112.7.11.240.455
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.455
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.455
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.455
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.455
4hnf16WCasein kinase I isoform delta2.7.11.10.455
2b52D42Cyclin-dependent kinase 22.7.11.220.454
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.454
3zxtACPDeath-associated protein kinase 12.7.11.10.454
4f630S7Fibroblast growth factor receptor 1/0.454
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.454
5auuLU2Death-associated protein kinase 12.7.11.10.454
1kkq471Peroxisome proliferator-activated receptor alpha/0.453
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.453
2chlDKICasein kinase I isoform gamma-32.7.11.10.453
2w1fL0FAurora kinase A2.7.11.10.453
3t9i3T9Serine/threonine-protein kinase pim-12.7.11.10.453
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.453
4ewqMWLMitogen-activated protein kinase 14/0.453
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.453
4ic7ANPMitogen-activated protein kinase 72.7.11.240.453
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.453
4nks2M2Fibroblast growth factor receptor 1/0.453
1m17AQ4Epidermal growth factor receptor2.7.10.10.452
1uyrD1LAcetyl-CoA carboxylase/0.452
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.452
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2uxuNARHTH-type transcriptional regulator TtgR/0.452
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.452
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.452
3bu5ATPInsulin receptor2.7.10.10.452
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.452
3lltANPProtein serine/threonine kinase-1/0.452
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.452
3zze6XPHepatocyte growth factor receptor2.7.10.10.452
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.452
4g160VMCasein kinase I isoform gamma-32.7.11.10.452
4hgt15GCasein kinase I isoform delta2.7.11.10.452
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1oiuN76Cyclin-dependent kinase 22.7.11.220.451
1p4fDRGDeath-associated protein kinase 12.7.11.10.451
2cchATPCyclin-dependent kinase 22.7.11.220.451
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.451
2j0m4STFocal adhesion kinase 12.7.10.20.451
2uxpCLMHTH-type transcriptional regulator TtgR/0.451
2yaaATPDeath-associated protein kinase 2/0.451
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.451
3oroAGSSerine/threonine protein kinase/0.451
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.451
4b99R4LMitogen-activated protein kinase 72.7.11.240.451
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.451
5cshATPCasein kinase II subunit alpha2.7.11.10.451
5e8wSTUTGF-beta receptor type-12.7.11.300.451
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.450
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.450
2b1pAIZMitogen-activated protein kinase 102.7.11.240.450
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.450
2vu3LZECyclin-dependent kinase 22.7.11.220.450
3nga3NGCasein kinase II subunit alpha2.7.11.10.450
3sheI85MAP kinase-activated protein kinase 32.7.11.10.450
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.450
4g1wG1WMitogen-activated protein kinase 82.7.11.240.450
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.450
4hvg19QTyrosine-protein kinase JAK32.7.10.20.450
4jboWPHAurora kinase A2.7.11.10.450
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.450
1bxoPP7Penicillopepsin-13.4.23.200.449
1e9hINRCyclin-dependent kinase 22.7.11.220.449
2bujSTUSerine/threonine-protein kinase 16/0.449
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3mdvCL6Cholesterol 24-hydroxylase/0.449
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
4bcqTJFCyclin-dependent kinase 22.7.11.220.449
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4jq7KJQEpidermal growth factor receptor2.7.10.10.449
5cu6ATPCasein kinase II subunit alpha2.7.11.10.449
1dawANPCasein kinase II subunit alpha2.7.11.10.448
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.448
2c5nCK8Cyclin-dependent kinase 22.7.11.220.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.448
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.448
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.448
3axwTIDCasein kinase II subunit alpha2.7.11.10.448
3e5aVX6Aurora kinase A2.7.11.10.448
3hllI45Mitogen-activated protein kinase 14/0.448
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.448
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.448
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4ix6ADPUncharacterized protein/0.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
4nc3ERM5-hydroxytryptamine receptor 2B/0.448
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.447
3a60STURibosomal protein S6 kinase beta-12.7.11.10.447
3gxlQIGTGF-beta receptor type-12.7.11.300.447
3kf7L9GMitogen-activated protein kinase 14/0.447
3l0lHC3Nuclear receptor ROR-gamma/0.447
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.447
3qtuX44Cyclin-dependent kinase 22.7.11.220.447
3unj0BXCyclin-dependent kinase 22.7.11.220.447
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.447
4c4g7RODual specificity protein kinase TTK2.7.12.10.447
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.447
5av4GENDeath-associated protein kinase 12.7.11.10.447
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1zeoC01Peroxisome proliferator-activated receptor gamma/0.446
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2fvdLIACyclin-dependent kinase 22.7.11.220.446
2ijmADPFocal adhesion kinase 12.7.10.20.446
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.446
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.446
3gu6ADPDeath-associated protein kinase 12.7.11.10.446
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.446
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4kba1QMCasein kinase I isoform delta2.7.11.10.446
4qmlANPSerine/threonine-protein kinase 242.7.11.10.446
1g5sI17Cyclin-dependent kinase 22.7.11.220.445
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.445
2j0j4STFocal adhesion kinase 12.7.10.20.445
2om9AJAPeroxisome proliferator-activated receptor gamma/0.445
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.445
2uzeC95Cyclin-dependent kinase 22.7.11.220.445
2uzlC94Cyclin-dependent kinase 22.7.11.220.445
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.445
3gwfFADCyclohexanone monooxygenase/0.445
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.445
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3mtlFEFCyclin-dependent kinase 162.7.11.220.445
3qaiXNNKetohexokinase/0.445
4gu610NFocal adhesion kinase 12.7.10.20.445
4o5qFADAlkyl hydroperoxide reductase subunit F1.8.10.445
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.445
2ovhAS0Progesterone receptor/0.444
2p33J07Mitogen-activated protein kinase 102.7.11.240.444
2pwlACPFibroblast growth factor receptor 2/0.444
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.444
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.444
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3vewADPnebramycin 5' synthase6.1.2.20.444
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4dgmAGICasein kinase II subunit alpha2.7.11.10.444
4fmqANPMitogen-activated protein kinase 12.7.11.240.444
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.444
4h9814QUncharacterized protein/0.444
4lxhC1EAlpha/beta hydrolase fold/0.444
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.444
1ke7LS3Cyclin-dependent kinase 22.7.11.220.443
1klkPMDDihydrofolate reductase1.5.1.30.443
1oguST8Cyclin-dependent kinase 22.7.11.220.443
1u4dDBQActivated CDC42 kinase 1/0.443
1u54ACPActivated CDC42 kinase 1/0.443
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.443
2pvhP19Casein kinase II subunit alpha2.7.11.10.443
2pvlP55Casein kinase II subunit alpha2.7.11.10.443
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.443
2wedPP6Penicillopepsin-13.4.23.200.443
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.443
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.443
3a7jADPSerine/threonine-protein kinase 242.7.11.10.443
3cv9VDXVitamin D3 dihydroxylase/0.443
3ielU5PRibonuclease TTHA02523.10.443
3litE15Protease/0.443
3t8oATPRhodopsin kinase/0.443
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.443
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.443
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.443
4xlvACPInsulin receptor2.7.10.10.443
1x2hLPALipoate-protein ligase A6.3.1.200.442
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2wecPP5Penicillopepsin-13.4.23.200.442
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.442
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.442
3efwAK8Aurora kinase A2.7.11.10.442
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.442
3vt9YI4Vitamin D3 receptor/0.442
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.442
4eon1ROCyclin-dependent kinase 22.7.11.220.442
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.442
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4gu94GUFocal adhesion kinase 12.7.10.20.442
4gub0Y4Casein kinase II subunit alpha2.7.11.10.442
4o0wADNAurora kinase A2.7.11.10.442
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.442
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1v79FR7Adenosine deaminase3.5.4.40.441
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.441
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.441
3blrCPBCyclin-dependent kinase 92.7.11.220.441
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.441
3qu0X40Cyclin-dependent kinase 22.7.11.220.441
3r3d4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3rni21ZCyclin-dependent kinase 22.7.11.220.441
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.441
4c3yFAD3-ketosteroid dehydrogenase/0.441
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.441
4jrvKJVEpidermal growth factor receptor2.7.10.10.441
4qmpDKISerine/threonine-protein kinase 242.7.11.10.441
5cvfATPCasein kinase II subunit alpha2.7.11.10.441
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.441
3uzcT4EAdenosine receptor A2a/0.441
1fmjRTLRetinol dehydratase/0.440
1h1r6CPCyclin-dependent kinase 22.7.11.220.440
1ke6LS2Cyclin-dependent kinase 22.7.11.220.440
1phgMYTCamphor 5-monooxygenase1.14.15.10.440
1ppjANYCytochrome b/0.440
2ay84TBAromatic-amino-acid aminotransferase2.6.1.570.440
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.440
2pulACPMethylthioribose kinase2.7.1.1000.440
2vagV25Dual specificity protein kinase CLK12.7.12.10.440
2w05FRTCyclin-dependent kinase 22.7.11.220.440
2wouZZFTGF-beta receptor type-12.7.11.300.440
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.440
3c50ADPRhodopsin kinase/0.440
3da24MDCarbonic anhydrase 134.2.1.10.440
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.440
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3vetADPnebramycin 5' synthase6.1.2.20.440
4c62XWWTyrosine-protein kinase JAK2/0.440
4fz60VGTyrosine-protein kinase SYK2.7.10.20.440
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4hvh19RTyrosine-protein kinase JAK32.7.10.20.440
4ux9ANPMitogen-activated protein kinase 82.7.11.240.440