Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 1.000 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.554 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.549 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.544 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.541 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.538 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.532 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.531 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.530 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.527 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.525 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.525 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.523 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.522 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.520 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.517 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.517 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.517 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.516 | |
| 3acj | KSS | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.515 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.513 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.512 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.512 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.510 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.510 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.508 | |
| 2pzr | ACP | Fibroblast growth factor receptor 2 | / | 0.507 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.504 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.503 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.503 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.503 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.501 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.501 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.501 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.500 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.500 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.500 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.499 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.497 | |
| 1di9 | MSQ | Mitogen-activated protein kinase 14 | / | 0.495 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.494 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.494 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.494 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.493 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.492 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.491 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.491 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.491 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.489 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.489 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.489 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.489 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.489 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.489 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.489 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.487 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.487 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.487 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.487 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.486 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.486 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.486 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.485 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.485 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.485 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.485 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.484 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.484 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.483 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.483 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.482 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.482 | |
| 3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.482 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.482 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.482 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.482 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.480 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.480 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.480 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.478 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.477 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.477 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.476 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.475 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.475 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.474 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.473 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.472 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.472 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.472 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.471 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.471 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.471 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.470 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.470 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.470 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.469 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.469 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.469 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.468 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.468 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.468 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.467 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.467 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.467 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.467 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.467 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.466 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.466 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.466 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.466 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.466 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 4lgg | VGG | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.465 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.464 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.463 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4agc | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.462 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.462 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.461 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.461 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.459 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 3bx5 | 304 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.458 | |
| 4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.458 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.457 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.457 | |
| 4joa | 3DK | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.457 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.456 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.455 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.455 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.455 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.455 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.455 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.454 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.454 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.454 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.453 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.453 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.453 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.452 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.452 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.452 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 2fgi | PD1 | Fibroblast growth factor receptor 1 | / | 0.451 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.451 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.451 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.451 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.450 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.450 | |
| 4ieb | ANP | Calmodulin-domain protein kinase 1 | / | 0.450 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.449 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.449 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4j1t | NAD | NAD/NADP transhydrogenase alpha subunit 1 | / | 0.449 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.449 | |
| 4mxy | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 1mes | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.448 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.448 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.448 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.448 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.447 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.447 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.447 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4az0 | S61 | Lysosomal protective protein | 3.4.16.5 | 0.447 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.447 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.447 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.446 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.446 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.446 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.446 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.446 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.446 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.445 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.445 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4j54 | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.444 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.444 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.444 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.444 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.443 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.443 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4l8u | 9AZ | Serum albumin | / | 0.443 | |
| 4uga | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.443 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.443 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.442 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.442 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 3liv | E16 | Protease | / | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.442 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.441 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.441 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.440 | |
| 1hw5 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2eau | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 2oxt | SAM | Genome polyprotein | / | 0.440 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.440 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3rdq | DTB | Streptavidin | / | 0.440 | |
| 3tba | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.440 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 4pd6 | URI | Nucleoside permease | / | 0.440 |