sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3zo7 | K6H | Muconolactone Delta-isomerase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3zo7 | K6H | Muconolactone Delta-isomerase | / | 1.000 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.519 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.512 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.512 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.509 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.502 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.499 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.497 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.493 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 1e79 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.486 | |
| 1e79 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.486 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.485 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.482 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 1hy3 | PPS | Estrogen sulfotransferase | 2.8.2.4 | 0.478 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.478 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.478 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.477 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.477 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.477 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.477 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.477 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.476 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.476 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.476 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.475 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 1vi0 | DCC | Fatty acid metabolism regulator protein | / | 0.474 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.473 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.473 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.473 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.472 | |
| 2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.472 | |
| 2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.472 | |
| 4imu | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.471 | |
| 2jiz | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.470 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.470 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.470 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.469 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.469 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.469 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.469 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.469 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.468 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.468 | |
| 1rxj | BNI | Streptavidin | / | 0.468 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.468 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.468 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.467 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.467 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1t9d | 1MM | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.467 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.467 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.467 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 5doz | NDP | JamJ | / | 0.467 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.466 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.466 | |
| 1o1v | TCH | Gastrotropin | / | 0.466 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.466 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.466 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.466 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.465 | |
| 1h9z | RWF | Serum albumin | / | 0.464 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.464 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.464 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.464 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2r0n | TGC | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.464 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.464 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.464 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.463 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.463 | |
| 2ok7 | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.463 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.463 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.463 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4ivr | N50 | Thymidine kinase | / | 0.463 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.462 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.461 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.461 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.461 | |
| 3x0c | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.461 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.461 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.460 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.460 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.460 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.460 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.460 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.460 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.460 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 1iah | ADP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.458 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.458 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.458 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.458 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.457 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 2z1w | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.456 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.456 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.456 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.456 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.456 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.456 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.456 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.456 | |
| 1h8h | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.455 | |
| 1h8h | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.455 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 2ejz | SAH | Diphthine synthase | / | 0.455 | |
| 2oac | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.455 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.455 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.455 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.455 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.454 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.454 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.454 | |
| 2mm3 | CHO | Gastrotropin | / | 0.454 | |
| 2oa7 | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.454 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.454 | |
| 1e2j | THM | Thymidine kinase | / | 0.453 | |
| 2c97 | JCL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 3c1o | NAP | Eugenol synthase | / | 0.453 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.453 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.453 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.453 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 1t9c | 1SM | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.452 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3fmz | 2T1 | Retinol-binding protein 4 | / | 0.452 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.452 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.451 | |
| 1n9m | BTN | Streptavidin | / | 0.451 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.451 | |
| 2g6i | HBI | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 3dh8 | B4N | Uncharacterized protein PA1000 | / | 0.451 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.451 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.451 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1nec | FMN | Oxygen-insensitive NAD(P)H nitroreductase | 1 | 0.450 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.450 | |
| 2b99 | RDL | Riboflavin synthase | 2.5.1.9 | 0.450 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.450 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.450 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.450 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.450 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.449 | |
| 1k2s | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 1nqx | RLP | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.449 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.449 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.449 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.448 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.448 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.448 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.448 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.448 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.448 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.448 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.447 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.447 | |
| 1swg | BTN | Streptavidin | / | 0.447 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.447 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.447 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 4fvy | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.447 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.446 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.446 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.446 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.446 | |
| 3jt5 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.446 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.446 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4a5y | G7X | Kinesin-like protein KIF11 | / | 0.446 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.446 | |
| 4coj | DTP | Uncharacterized protein | / | 0.446 | |
| 4cth | RDF | Neprilysin | / | 0.446 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.446 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.446 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.446 | |
| 1i05 | LTL | Major urinary protein 6 | / | 0.445 | |
| 1n0h | CIE | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.445 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2par | TMP | 5'-deoxynucleotidase YfbR | / | 0.445 | |
| 2w03 | ADN | AcsD | / | 0.445 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.445 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.445 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.445 | |
| 3jt8 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4ag9 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.445 | |
| 4edz | 0O5 | Hematopoietic prostaglandin D synthase | / | 0.445 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 4xug | F9F | Tryptophan synthase alpha chain | / | 0.445 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 5ckw | ANP | Uncharacterized protein | / | 0.445 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.445 | |
| 1hlk | 113 | Metallo-beta-lactamase type 2 | / | 0.444 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.444 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.444 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.444 | |
| 3jt7 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3n61 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3nos | H4B | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.444 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.444 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4gd9 | BTN | Streptavidin | / | 0.444 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.444 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.444 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.444 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.444 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.443 | |
| 1zdw | FLV | Prenyltransferase | / | 0.443 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 3eq6 | BCO | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.443 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.443 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4gqe | 6KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 1bmf | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 1bmf | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1i58 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 1q6p | 213 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.442 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.442 | |
| 2nom | DUT | Poly(A) polymerase, putative | / | 0.442 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.442 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.442 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.442 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.442 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.442 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.442 | |
| 1avd | BTN | Avidin | / | 0.441 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.441 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.441 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.441 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.441 | |
| 1sm9 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.441 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.441 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.441 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 2b56 | UTP | RNA editing complex protein MP57 | / | 0.441 | |
| 2ix5 | CAA | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.441 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.441 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.441 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3jwt | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3p9t | TCL | Repressor | / | 0.441 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.441 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.441 | |
| 1ddt | APU | Diphtheria toxin | / | 0.440 | |
| 1mtc | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.440 | |
| 1n5t | OAL | ActVA 6 protein | / | 0.440 | |
| 1q1g | MTI | Purine nucleoside phosphorylase | / | 0.440 | |
| 1qru | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.440 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.440 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.440 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.440 | |
| 2vcq | D25 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.440 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.440 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.440 | |
| 3zpo | K0I | Histone demethylase UTY | 1.14.11 | 0.440 | |
| 3zrr | PXG | Serine-pyruvate aminotransferase (AgxT) | / | 0.440 | |
| 4bqw | QNM | Egl nine homolog 1 | / | 0.440 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 4iah | 1DX | Alr2278 protein | / | 0.440 | |
| 4lv8 | ADP | Rhoptry protein 5 C | / | 0.440 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.440 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.440 |