sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p6d | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2p6d | SAH | Diphthine synthase | / | 1.000 | |
| 2emr | SAH | Diphthine synthase | / | 0.877 | |
| 2ehl | SAH | Diphthine synthase | / | 0.873 | |
| 2eka | SAH | Diphthine synthase | / | 0.852 | |
| 2ele | SAH | Diphthine synthase | / | 0.847 | |
| 2pcm | SAH | Diphthine synthase | / | 0.835 | |
| 2emu | SAH | Diphthine synthase | / | 0.829 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.822 | |
| 2eni | SAH | Diphthine synthase | / | 0.820 | |
| 2dxv | SAH | Diphthine synthase | / | 0.816 | |
| 2ejk | SAH | Diphthine synthase | / | 0.810 | |
| 2e7r | SAH | Diphthine synthase | / | 0.806 | |
| 2dxw | SAH | Diphthine synthase | / | 0.800 | |
| 2pcg | SAH | Diphthine synthase | / | 0.789 | |
| 2owk | SAH | Diphthine synthase | / | 0.786 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.776 | |
| 2e8s | SAH | Diphthine synthase | / | 0.774 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.772 | |
| 2p6k | SAH | Diphthine synthase | / | 0.768 | |
| 2egs | SAH | Diphthine synthase | / | 0.765 | |
| 2egb | SAH | Diphthine synthase | / | 0.763 | |
| 2e8r | SAH | Diphthine synthase | / | 0.753 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.752 | |
| 2dsg | SAH | Diphthine synthase | / | 0.750 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.739 | |
| 2egl | SAH | Diphthine synthase | / | 0.738 | |
| 2p5c | SAH | Diphthine synthase | / | 0.733 | |
| 2p2x | SAH | Diphthine synthase | / | 0.729 | |
| 2e8q | SAH | Diphthine synthase | / | 0.724 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.724 | |
| 2dxx | SAH | Diphthine synthase | / | 0.720 | |
| 2p5f | SAH | Diphthine synthase | / | 0.720 | |
| 2pck | SAH | Diphthine synthase | / | 0.720 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.716 | |
| 2e08 | SAH | Diphthine synthase | / | 0.712 | |
| 2e16 | SAH | Diphthine synthase | / | 0.711 | |
| 2eld | SAH | Diphthine synthase | / | 0.692 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.692 | |
| 1vce | SAH | Diphthine synthase | / | 0.687 | |
| 2hux | SAH | Diphthine synthase | / | 0.684 | |
| 2dsi | SAH | Diphthine synthase | / | 0.682 | |
| 2en5 | SAH | Diphthine synthase | / | 0.682 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.680 | |
| 2pch | SAH | Diphthine synthase | / | 0.677 | |
| 2hut | SAH | Diphthine synthase | / | 0.675 | |
| 2el0 | SAH | Diphthine synthase | / | 0.672 | |
| 2el3 | SAH | Diphthine synthase | / | 0.663 | |
| 2p6i | SAH | Diphthine synthase | / | 0.663 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.658 | |
| 2owv | SAH | Diphthine synthase | / | 0.649 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.648 | |
| 2owg | SAH | Diphthine synthase | / | 0.647 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.645 | |
| 2huv | SAH | Diphthine synthase | / | 0.645 | |
| 1wng | SAH | Diphthine synthase | / | 0.639 | |
| 2e4n | SAH | Diphthine synthase | / | 0.639 | |
| 2e8h | SAH | Diphthine synthase | / | 0.638 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.638 | |
| 2pci | SAH | Diphthine synthase | / | 0.638 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.633 | |
| 2p9d | SAH | Diphthine synthase | / | 0.624 | |
| 2dek | SAH | Diphthine synthase | / | 0.623 | |
| 2e15 | SAH | Diphthine synthase | / | 0.619 | |
| 2pca | SAH | Diphthine synthase | / | 0.617 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.608 | |
| 2eeq | SAH | Diphthine synthase | / | 0.605 | |
| 2e17 | SAH | Diphthine synthase | / | 0.603 | |
| 2p6l | SAH | Diphthine synthase | / | 0.589 | |
| 2z6r | SAH | Diphthine synthase | / | 0.582 | |
| 2owu | SAH | Diphthine synthase | / | 0.581 | |
| 2owf | SAH | Diphthine synthase | / | 0.578 | |
| 2ejz | SAH | Diphthine synthase | / | 0.576 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.574 | |
| 2dsh | SAH | Diphthine synthase | / | 0.573 | |
| 2ejj | SAH | Diphthine synthase | / | 0.567 | |
| 2huq | SAH | Diphthine synthase | / | 0.566 | |
| 2e07 | SAH | Diphthine synthase | / | 0.536 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.522 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.496 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.491 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.490 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.489 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.487 | |
| 3a3g | DLZ | Lumazine protein | / | 0.487 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.482 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.479 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.479 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.477 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.477 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.476 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.476 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.473 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.473 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.473 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.472 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.470 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.469 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.468 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.467 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.465 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.464 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.463 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.462 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.462 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 2y3s | TIR | TamL | / | 0.462 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.462 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.462 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.462 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.462 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.461 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.461 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.460 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.460 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.460 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.460 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.459 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.458 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.458 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.458 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.457 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.457 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.456 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.455 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.455 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.455 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.455 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.455 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.455 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.454 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.454 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.454 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.453 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.452 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.452 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.452 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.451 | |
| 1zio | AP5 | Adenylate kinase | / | 0.451 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.450 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.450 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.450 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.450 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.449 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.449 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.448 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.448 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.448 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.448 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.447 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.447 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.447 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.447 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.446 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.446 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.445 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.445 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.445 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.445 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.445 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.444 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2y3r | TRK | TamL | / | 0.444 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.444 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.444 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.444 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.443 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.443 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.442 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.442 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.442 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.442 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.441 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.441 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.441 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.441 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.440 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.440 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.440 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.440 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.440 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.440 |