sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 1.000 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.625 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.609 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.594 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.589 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.580 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.565 | |
| 2nli | FMN | Lactate oxidase | / | 0.563 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.560 | |
| 2j6x | FMN | Lactate oxidase | / | 0.546 | |
| 2e77 | FMN | Lactate oxidase | / | 0.541 | |
| 5ebu | FMN | Lactate oxidase | / | 0.541 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.531 | |
| 4rje | FNR | Lactate oxidase | / | 0.528 | |
| 3hf3 | FMN | Chromate reductase | / | 0.526 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.511 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.510 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.500 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.497 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.491 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 2du2 | FMN | Lactate oxidase | / | 0.490 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.485 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.484 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.483 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.482 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.482 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.480 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.480 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.480 | |
| 2zfa | FMN | Lactate oxidase | / | 0.479 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.479 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.477 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.475 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.475 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.474 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.473 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.472 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.470 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.470 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.468 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.468 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.467 | |
| 1nja | DCM | Thymidylate synthase | / | 0.467 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.467 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.467 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.467 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.467 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.466 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.465 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.465 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.464 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.464 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.463 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.463 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.462 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.461 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.461 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.460 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.460 | |
| 3suf | SUE | Polyprotein | / | 0.460 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.460 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.460 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.460 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.460 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.459 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.459 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.459 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.459 | |
| 4die | C5P | Cytidylate kinase | / | 0.459 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.459 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.458 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.458 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.458 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.458 | |
| 5jjs | SAH | Genome polyprotein | / | 0.458 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.457 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.457 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 1tsy | UMP | Thymidylate synthase | / | 0.456 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.456 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.456 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.455 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.455 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.455 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.455 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.455 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.455 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.455 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.455 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.455 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.454 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.454 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.454 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.454 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.454 | |
| 1h7w | FMN | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.453 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.453 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.453 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.453 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.453 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.452 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.452 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.452 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.452 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.452 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.452 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.452 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.452 | |
| 1bid | UMP | Thymidylate synthase | / | 0.451 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.451 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.451 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.451 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.451 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.451 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.451 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.451 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.451 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.450 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.450 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.450 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.450 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.450 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.450 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.449 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.449 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.449 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.449 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.449 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.449 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.448 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.448 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.448 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.448 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.448 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.447 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.447 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.447 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.447 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.447 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.447 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.446 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.446 | |
| 2bun | FAD | AppA protein | / | 0.446 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.446 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.446 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3pxv | FMN | Nitroreductase | / | 0.446 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.446 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 1jmf | UMP | Thymidylate synthase | / | 0.445 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.445 | |
| 2qln | F59 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.445 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.445 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.444 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.444 | |
| 1njd | UMP | Thymidylate synthase | / | 0.444 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.444 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.444 | |
| 3to0 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.444 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.444 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.444 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.444 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.444 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.443 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.442 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.442 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.442 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.442 | |
| 3uce | NDP | Dehydrogenase | / | 0.442 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3x22 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.442 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.442 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.442 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.442 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.442 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.442 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.442 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3a3g | DLZ | Lumazine protein | / | 0.441 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3elu | SAM | Methyltransferase | / | 0.441 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.441 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.441 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.441 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.441 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.441 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.441 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 1axe | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.440 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.440 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.440 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4blr | UTP | NTPase P4 | / | 0.440 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.440 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4jic | FMN | GTN Reductase | / | 0.440 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.440 |