Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2obf | F83 | Phenylethanolamine N-methyltransferase | 2.1.1.28 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2obf | F83 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 1.000 | |
| 2g8n | F83 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.684 | |
| 2ony | TMJ | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.623 | |
| 2opb | F21 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.620 | |
| 2onz | TMJ | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.618 | |
| 2g72 | F21 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.589 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.508 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.506 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.505 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.492 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.491 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.491 | |
| 4n1f | CZH | Obelin | / | 0.491 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.490 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.490 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.489 | |
| 1uhj | CZB | Aequorin-2 | / | 0.488 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.488 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.483 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.482 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.481 | |
| 1qv1 | CZH | Obelin | / | 0.480 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.479 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.478 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.478 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.476 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.476 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.474 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.474 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.474 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.473 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.473 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.473 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.472 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.471 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.470 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.470 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.470 | |
| 1qv0 | CZH | Obelin | / | 0.469 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.469 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.469 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.469 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.468 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.468 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.468 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.467 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.467 | |
| 3up0 | D7S | aceDAF-12 | / | 0.467 | |
| 4f6x | ZYL | Dehydrosqualene synthase | / | 0.467 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.466 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.465 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.465 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.465 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.464 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.464 | |
| 1e2l | TMC | Thymidine kinase | / | 0.464 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.464 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.464 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.463 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.463 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.462 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.462 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.462 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 3n3b | FMN | Protein NrdI | / | 0.462 | |
| 1ddt | APU | Diphtheria toxin | / | 0.461 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.461 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.461 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.461 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 4ea0 | 651 | Dehydrosqualene synthase | / | 0.460 | |
| 4fj1 | GEN | 17beta-hydroxysteroid dehydrogenase | / | 0.460 | |
| 4yal | 2AM | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.459 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.459 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.458 | |
| 2clh | F19 | Tryptophan synthase alpha chain | / | 0.458 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.458 | |
| 3dlc | SAM | SAM (And some other nucleotide) binding motif:Generic methyltransferase | / | 0.458 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4iqq | D16 | Thymidylate synthase | / | 0.458 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.458 | |
| 4n1g | CEI | Obelin | / | 0.458 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.457 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.457 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.457 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.457 | |
| 1dia | L24 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.456 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.456 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3ndj | JHZ | Methyltransferase | / | 0.456 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.456 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.455 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.455 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2trs | IPL | Tryptophan synthase alpha chain | / | 0.455 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 2z2d | HSI | Macrophage metalloelastase | 3.4.24.65 | 0.455 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.455 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.455 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.455 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.454 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.454 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.454 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.454 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.454 | |
| 3ele | PLP | Aminotransferase | / | 0.454 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.454 | |
| 3qp8 | HL0 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.454 | |
| 3v4e | COA | Putative acetyltransferase SACOL2570 | 2.3.1 | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 1fuy | FIP | Tryptophan synthase alpha chain | / | 0.453 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.453 | |
| 1kf6 | HQO | Fumarate reductase iron-sulfur subunit | 1.3.5.1 | 0.453 | |
| 1kf6 | HQO | Fumarate reductase subunit C | / | 0.453 | |
| 1kf6 | HQO | Fumarate reductase subunit D | / | 0.453 | |
| 1nw4 | IMH | Purine nucleoside phosphorylase | / | 0.453 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.453 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.453 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.453 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.453 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.453 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.453 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 4gd9 | BTN | Streptavidin | / | 0.453 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.453 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1hqt | NAP | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.452 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.452 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.452 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.452 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.452 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.452 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.452 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 5d4v | YGP | Uncharacterized protein MJ0489 | / | 0.452 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.451 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.451 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3bmc | FOL | Pteridine reductase | / | 0.451 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.451 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.451 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.451 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2jfz | 003 | Glutamate racemase | / | 0.450 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.450 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.450 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.450 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.449 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.449 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.449 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.449 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.448 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.448 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.448 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.448 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.448 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.448 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.448 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.448 | |
| 1mc0 | PCG | cGMP-dependent 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1p1b | SAH | Guanidinoacetate N-methyltransferase | 2.1.1.2 | 0.447 | |
| 1tvc | FDA | Methane monooxygenase component C | 1.14.13.25 | 0.447 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1z3w | IDC | Glucanase | / | 0.447 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.447 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1a50 | FIP | Tryptophan synthase alpha chain | / | 0.446 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 1eio | GCH | Gastrotropin | / | 0.446 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.446 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.446 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.446 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.446 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.446 | |
| 1jf0 | CZH | Obelin | / | 0.445 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1lke | DOG | Bilin-binding protein | / | 0.445 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.445 | |
| 1z9a | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.445 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.445 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.445 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.445 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.445 | |
| 3n39 | FMN | Protein NrdI | / | 0.445 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.445 | |
| 4fc0 | 0T2 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 4hcy | 0YN | Transketolase | / | 0.445 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.444 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.444 | |
| 1tys | DHF | Thymidylate synthase | / | 0.444 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4fr8 | TNG | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.443 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2qjp | ANJ | Cytochrome b | / | 0.443 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3arv | SAU | Chitinase A | / | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.443 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 3qp6 | HL6 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.443 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.443 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.443 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.443 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.442 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.442 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.442 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.442 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.442 | |
| 3p2k | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.442 | |
| 3qwh | KMP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.442 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.442 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4buf | F36 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.442 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.442 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.441 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.441 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.441 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.441 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.441 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.441 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.441 | |
| 3mcv | MCV | Pteridine reductase | / | 0.441 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.441 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.441 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.440 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.440 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.440 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.440 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.440 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.440 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.440 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.440 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.440 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.440 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.440 |