sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 1.000 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.600 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.577 | |
| 3k8o | 229 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.571 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.563 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.554 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.550 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.538 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.537 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.529 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.528 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.525 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.519 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.515 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.511 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.509 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.509 | |
| 3f8w | ADN | Purine nucleoside phosphorylase | / | 0.505 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.504 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.501 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.498 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.497 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.496 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.494 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.493 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.489 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.488 | |
| 1zdw | FLV | Prenyltransferase | / | 0.488 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.487 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.486 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.484 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.483 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.482 | |
| 2e15 | SAH | Diphthine synthase | / | 0.481 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.480 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.479 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.478 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 5dp2 | NAP | CurF | / | 0.478 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.476 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.475 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.475 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.475 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.474 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.473 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.473 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.471 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.471 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.471 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.469 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.469 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.467 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.467 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.466 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.466 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.466 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.466 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.466 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.465 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.465 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.464 | |
| 2dsh | SAH | Diphthine synthase | / | 0.464 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.464 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.463 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.462 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.462 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.462 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.462 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.461 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.461 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.461 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.460 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.460 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.460 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.459 | |
| 3clt | FAD | Electron transfer flavoprotein subunit alpha | / | 0.459 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.459 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.459 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.459 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.459 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.457 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.457 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.457 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.457 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.456 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.456 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.455 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.455 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.455 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.455 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.454 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.454 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.454 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3ndj | JHZ | Methyltransferase | / | 0.454 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.454 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.454 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.453 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.453 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.453 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2jgs | BTN | Avidin | / | 0.453 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.453 | |
| 1e0a | GNP | Cell division control protein 42 homolog | / | 0.452 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.452 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.452 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.452 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.452 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.452 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.452 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4e2d | FMN | Dehydrogenase | / | 0.452 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.452 | |
| 4irn | FAD | AnaB | / | 0.452 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.452 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.451 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.451 | |
| 2pck | SAH | Diphthine synthase | / | 0.451 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.451 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.451 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.451 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4e32 | DWN | Methyltransferase | / | 0.451 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.451 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.451 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.450 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.450 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4hdg | GTP | Genome polyprotein | 2.7.7.48 | 0.450 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.450 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 2p5c | SAH | Diphthine synthase | / | 0.449 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.449 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.449 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.448 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.448 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.448 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.448 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.447 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.447 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 2e07 | SAH | Diphthine synthase | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.447 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.447 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.447 | |
| 2e16 | SAH | Diphthine synthase | / | 0.446 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.446 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2x90 | EAL | Angiotensin-converting enzyme | 3.4.15.1 | 0.446 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.446 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.446 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.445 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.445 | |
| 2eka | SAH | Diphthine synthase | / | 0.445 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.445 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.445 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 3up0 | D7S | aceDAF-12 | / | 0.445 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.445 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.445 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.444 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.444 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.444 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.444 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.444 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 1lcb | TMP | Thymidylate synthase | / | 0.443 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 1til | ATP | Anti-sigma F factor | / | 0.443 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.443 | |
| 2cdu | FAD | NADH oxidase | / | 0.443 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.443 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.443 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.443 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.443 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2egl | SAH | Diphthine synthase | / | 0.442 | |
| 2fze | APR | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.442 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.442 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.442 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.442 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.441 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.441 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.441 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.440 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.440 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3l7d | DK5 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.440 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4e2b | FMN | Dehydrogenase | / | 0.440 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 |