sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 1.000 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.738 | |
| 1zao | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.663 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.590 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.535 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.525 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.518 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.516 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.515 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.515 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.514 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.514 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.512 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.511 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.511 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.508 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.507 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.505 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.503 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.503 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.502 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.501 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.501 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.500 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.499 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.498 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.498 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.498 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.497 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.496 | |
| 1jkl | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.494 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.493 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.493 | |
| 3otu | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.492 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.491 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.491 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.491 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.491 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.490 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.489 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.488 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.486 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.485 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.485 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.485 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.484 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.484 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.483 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.483 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.482 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.481 | |
| 4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.480 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.480 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.480 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.478 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.477 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 3bhy | 7CP | Death-associated protein kinase 3 | / | 0.476 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.476 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.476 | |
| 5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.476 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.475 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.475 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.473 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.472 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.472 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.472 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.471 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.471 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.470 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.470 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.469 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.469 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.468 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.468 | |
| 3e7t | B14 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.468 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.467 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.463 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.462 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.462 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.462 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.461 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.461 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.461 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.460 | |
| 3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.460 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.460 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.460 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2r3r | 6SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.459 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.458 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.458 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.457 | |
| 2xan | ANP | Inositol-pentakisphosphate 2-kinase | 2.7.1.158 | 0.457 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 3umw | 596 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.457 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.457 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.457 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.456 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 4lv7 | ADP | Inositol-pentakisphosphate 2-kinase | 2.7.1.158 | 0.456 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.455 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.455 | |
| 4wlv | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.455 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.455 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.454 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4jik | 1KO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 5av4 | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 1xha | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 3lij | ANP | Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands | / | 0.453 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.452 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.452 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.452 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.452 | |
| 2ad5 | ADP | CTP synthase | / | 0.451 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.451 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.451 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.451 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.450 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.450 | |
| 2yyu | C5P | Orotidine 5'-phosphate decarboxylase | / | 0.450 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.450 | |
| 3r7y | Z04 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.450 | |
| 4y12 | AGS | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.450 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 4aqk | ADP | Inositol-pentakisphosphate 2-kinase | 2.7.1.158 | 0.449 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1q3d | STU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.448 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.448 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.448 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.448 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.447 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.447 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.447 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 4j6i | 1JV | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.447 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.447 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.446 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.446 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.446 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.446 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.446 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3r73 | X87 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4brx | KGW | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 4eol | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.445 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.445 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.445 | |
| 5auz | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.444 | |
| 3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4axd | ANP | Inositol-pentakisphosphate 2-kinase | 2.7.1.158 | 0.444 | |
| 4dta | ADN | APH(2'')-Id | / | 0.444 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.444 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.444 | |
| 5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.444 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3u9e | COA | Lmo1369 protein | / | 0.443 | |
| 3zok | NAD | 3-dehydroquinate synthase, chloroplastic | 4.2.3.4 | 0.443 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 4axf | ANP | Inositol-pentakisphosphate 2-kinase | 2.7.1.158 | 0.443 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.443 | |
| 1c6z | ROC | Protease | / | 0.442 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 1sx4 | ADP | 60 kDa chaperonin | / | 0.442 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2ydk | YDK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.442 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.442 | |
| 1c6y | MK1 | Protease | / | 0.441 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.441 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.441 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2pc4 | ASP_TRP_ASN | Fructose-bisphosphate aldolase | 4.1.2.13 | 0.441 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3q92 | XNB | Ketohexokinase | / | 0.441 | |
| 3qxo | X65 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4fv2 | EK5 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4izy | 1J2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 1h1q | 2A6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2vo3 | M04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3em4 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.440 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.440 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.440 | |
| 4j99 | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 |