sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1beu | IPL | Tryptophan synthase alpha chain |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1beu | IPL | Tryptophan synthase alpha chain | / | 1.000 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.695 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.633 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.592 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.592 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.569 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.569 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.504 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.493 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.490 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.484 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.482 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.480 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.480 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.479 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.479 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.479 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.479 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.478 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.477 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.475 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.475 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.475 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.475 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.474 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.473 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.471 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.471 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.471 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.469 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.468 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.467 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.467 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.467 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.467 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.466 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.466 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.466 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.465 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.465 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.464 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.464 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.463 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.463 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.463 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.463 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.463 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.463 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.462 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.462 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.461 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.461 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.460 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.460 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.460 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.460 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.459 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.459 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.459 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.459 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.458 | |
| 4jic | FMN | GTN Reductase | / | 0.458 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.458 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.458 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.457 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.457 | |
| 2dsi | SAH | Diphthine synthase | / | 0.457 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.457 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 3v2u | ATP | Protein GAL3 | / | 0.456 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.456 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.456 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.455 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.455 | |
| 3u9e | COA | Lmo1369 protein | / | 0.455 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.454 | |
| 1qy5 | NEC | Endoplasmin | / | 0.454 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.454 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.454 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.454 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.454 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.454 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.453 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.453 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.453 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.453 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.452 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.452 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.452 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.452 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.452 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.452 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.452 | |
| 5ftf | ADP | TPR domain protein | / | 0.452 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.451 | |
| 2e16 | SAH | Diphthine synthase | / | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3n0b | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.451 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.451 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.450 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.450 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.450 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.449 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.449 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.449 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.448 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.448 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.448 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.448 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.447 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.447 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.447 | |
| 2e17 | SAH | Diphthine synthase | / | 0.447 | |
| 2e8r | SAH | Diphthine synthase | / | 0.447 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.447 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.447 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.447 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.447 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.447 | |
| 2dsg | SAH | Diphthine synthase | / | 0.446 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.446 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.446 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.446 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.445 | |
| 2pci | SAH | Diphthine synthase | / | 0.445 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.445 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.445 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.445 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.444 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.444 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.444 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.444 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.444 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.444 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.443 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.443 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.443 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.443 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.443 | |
| 1a5s | FIP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.442 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.442 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.442 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3iaa | TYD | CalG2 | / | 0.442 | |
| 4azm | T4B | Fatty acid-binding protein, epidermal | / | 0.442 | |
| 4blr | UTP | NTPase P4 | / | 0.442 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.442 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.442 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.442 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.441 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4irn | FAD | AnaB | / | 0.441 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.441 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.440 | |
| 1c6y | MK1 | Protease | / | 0.440 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 2egb | SAH | Diphthine synthase | / | 0.440 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.440 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.440 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.440 |