sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 1.000 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.594 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.591 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.589 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.585 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.581 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.575 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.571 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.570 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.567 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.567 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.566 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.566 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.565 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.563 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.562 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.558 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.557 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.556 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.555 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.553 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.548 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.537 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.535 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.535 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.514 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.508 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.499 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.483 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.483 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.476 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4i5i | 4I5 | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.475 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1r2j | FAD | FkbI | / | 0.474 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.473 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 1ppj | ANY | Cytochrome b | / | 0.471 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.470 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.470 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.468 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4okx | 198 | Androgen receptor | / | 0.467 | |
| 1qy5 | NEC | Endoplasmin | / | 0.466 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.466 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.466 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.464 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.464 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.464 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.463 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.462 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.462 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.462 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.462 | |
| 3v49 | PK0 | Androgen receptor | / | 0.462 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.462 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.461 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.461 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.460 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.460 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.460 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.460 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.460 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.460 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.459 | |
| 4l4x | NDP | AmphI | / | 0.459 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.458 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.458 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.458 | |
| 3v4a | PK1 | Androgen receptor | / | 0.458 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.458 | |
| 4yqf | GDP | Septin-9 | / | 0.458 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.457 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.456 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.456 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.456 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.455 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1fml | RTL | Retinol dehydratase | / | 0.455 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.455 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.454 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.454 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.454 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.454 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.453 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3zuy | TCH | Transporter | / | 0.453 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.453 | |
| 5a3c | NAD | SIR2 family protein | / | 0.453 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1qy8 | RDI | Endoplasmin | / | 0.452 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.452 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.452 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.451 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.451 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4pd6 | URI | Nucleoside permease | / | 0.451 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.451 | |
| 1u0z | RDC | Endoplasmin | / | 0.450 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.450 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.450 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.449 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.449 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.448 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.448 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.448 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.448 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.448 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.448 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.447 | |
| 1u0y | PA7 | Endoplasmin | / | 0.447 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.447 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.447 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.447 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.447 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.446 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.446 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.446 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.446 | |
| 2xvw | 9NR | Serum albumin | / | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.446 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.446 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.446 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.445 | |
| 1eio | GCH | Gastrotropin | / | 0.445 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.445 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.445 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.445 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.445 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.444 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.444 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.444 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.444 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 1flm | FMN | FMN-binding protein | / | 0.443 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.443 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.443 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.443 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.443 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.443 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.443 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.443 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.443 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.443 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.442 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.442 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.442 | |
| 2xvv | 9DN | Serum albumin | / | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.442 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4ok1 | 198 | Androgen receptor | / | 0.442 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.441 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.441 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2bxm | IMN | Serum albumin | / | 0.441 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.441 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.441 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.441 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.441 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.441 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.441 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 3a6r | FMN | FMN-binding protein | / | 0.440 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.440 |