sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 1.000 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.755 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.677 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.638 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.570 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.544 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.542 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.538 | |
| 4ros | APR | Malate dehydrogenase | / | 0.531 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.528 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.525 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.510 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.507 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.507 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.506 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.505 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.504 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.502 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.496 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.496 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.494 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.494 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.493 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.486 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.485 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.485 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.484 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.482 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.481 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.480 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.480 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.478 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.478 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.476 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.476 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.475 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.474 | |
| 4jic | FMN | GTN Reductase | / | 0.474 | |
| 5mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.474 | |
| 4fnc | HMU | G/T mismatch-specific thymine DNA glycosylase | 3.2.2.29 | 0.473 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.472 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.472 | |
| 5a3b | APR | SIR2 family protein | / | 0.472 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.471 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.471 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.470 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.470 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.468 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.468 | |
| 3eku | CY9 | Actin-5C | / | 0.468 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.468 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.467 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.467 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.467 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.466 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.466 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.466 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.465 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.465 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.465 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.465 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.464 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.464 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4e2d | FMN | Dehydrogenase | / | 0.463 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.462 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.462 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.461 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.461 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4bls | APC | NTPase P4 | / | 0.460 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.459 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.458 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.458 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.458 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.458 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.458 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.458 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.457 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.457 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.457 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.456 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.456 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.456 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.455 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.455 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.455 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.455 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 3a3g | DLZ | Lumazine protein | / | 0.455 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.455 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.454 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.454 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4k81 | GTP | GTPase HRas | / | 0.454 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.453 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.452 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.452 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.452 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.452 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.451 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.451 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.451 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.451 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.451 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.450 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.450 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.450 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.450 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.449 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.449 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.449 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.449 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.448 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.448 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.448 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 5a3c | NAD | SIR2 family protein | / | 0.448 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.447 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.447 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.447 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.447 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.447 | |
| 1eio | GCH | Gastrotropin | / | 0.446 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.446 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.446 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.446 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.446 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.445 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.445 | |
| 2ohv | NHL | Glutamate racemase | / | 0.445 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.445 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.445 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.445 | |
| 4f4q | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.445 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.445 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.444 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.444 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.444 | |
| 3ieu | GDP | GTPase Era | / | 0.444 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.444 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.444 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.444 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.443 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.443 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.443 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.443 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.442 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.442 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.442 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.442 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4ajj | 88R | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.441 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.441 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.441 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.441 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.440 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.440 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |