Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 1.000 | |
| 4fyn | 0VE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.596 | |
| 4fz6 | 0VG | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.591 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.542 | |
| 4fyo | 0VF | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.528 | |
| 4gfg | 0XF | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.528 | |
| 3emg | 685 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.522 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.520 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.512 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.512 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.512 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.511 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.509 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.509 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.507 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.507 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.507 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.505 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.503 | |
| 2q0b | ACP | Fibroblast growth factor receptor 2 | / | 0.502 | |
| 4f4p | 0SB | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.502 | |
| 3du8 | 553 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.501 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.501 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.500 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.500 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.500 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.499 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.499 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.498 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.498 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.498 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.497 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.497 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.497 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.497 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.495 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.494 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.494 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.493 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.493 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.493 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.493 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.493 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.492 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.491 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.491 | |
| 1q3d | STU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.490 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.490 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.490 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.489 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.489 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.489 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.489 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.488 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.486 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.486 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.485 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.485 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.484 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.484 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.484 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.484 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.483 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.483 | |
| 1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.482 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.482 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.482 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.482 | |
| 4fz7 | 0VH | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.481 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.481 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.480 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.480 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.480 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.479 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.479 | |
| 3sd0 | TSK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.479 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.479 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.479 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.478 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.478 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.477 | |
| 2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.477 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.476 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.476 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.475 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.475 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.475 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.474 | |
| 3vjn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.473 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.473 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 4w9w | YDJ | BMP-2-inducible protein kinase | 2.7.11.1 | 0.472 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.471 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.471 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.469 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.469 | |
| 3q3b | 55E | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.469 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.469 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.469 | |
| 4fto | 3HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.469 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.468 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.468 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.468 | |
| 4ccu | AWF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.468 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.468 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.467 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.467 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.467 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.467 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.466 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.466 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.466 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.466 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
| 4b7t | CWT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.466 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.465 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.464 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.464 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.463 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.463 | |
| 2zoq | 5ID | Mitogen-activated protein kinase 3 | 2.7.11.24 | 0.463 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 3lq5 | SLQ | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.463 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.463 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.462 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.462 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.462 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.461 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.460 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.460 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 3bhy | 7CP | Death-associated protein kinase 3 | / | 0.459 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.459 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.459 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4g3e | 0WC | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.459 | |
| 4joa | 3DK | ALK tyrosine kinase receptor | 2.7.10.1 | 0.459 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.458 | |
| 2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.458 | |
| 2y7j | B49 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | 2.7.11.19 | 0.457 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.456 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.456 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.456 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.455 | |
| 2x2k | X2K | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.455 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.455 | |
| 3b2t | M33 | Fibroblast growth factor receptor 2 | / | 0.455 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.455 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.454 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.454 | |
| 3v3v | MYU | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.454 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.454 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.454 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.453 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.453 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.453 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.453 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
| 3owk | 18E | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.452 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.452 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 4jrn | ANP | Rhoptry kinase family protein | / | 0.452 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.451 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.450 | |
| 4cfn | JYM | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 4erk | OLO | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.450 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.450 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.449 | |
| 5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.448 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.448 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.448 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.446 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.446 | |
| 1wvy | STU | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3rm7 | 19Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.445 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.445 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3qxo | X65 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.444 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.444 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.443 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.443 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.443 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.442 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.442 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.441 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4fv4 | EK7 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 |