sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ing | NDP | Homoserine dehydrogenase related protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 1.000 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.495 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.490 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.487 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.483 | |
| 4jic | FMN | GTN Reductase | / | 0.483 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.482 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.476 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.475 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.475 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 4blr | UTP | NTPase P4 | / | 0.475 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.473 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.473 | |
| 1i6l | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.471 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.471 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.471 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.471 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.470 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.470 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.468 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.467 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.467 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.466 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.466 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.465 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.465 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.464 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.464 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.463 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.463 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.463 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.463 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.461 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.461 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.461 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.461 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.461 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.461 | |
| 4e2b | FMN | Dehydrogenase | / | 0.461 | |
| 5cyo | GDP | Septin-9 | / | 0.461 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.460 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.460 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.460 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.460 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.459 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.459 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.459 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.459 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.458 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.458 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.458 | |
| 5dp2 | NAP | CurF | / | 0.458 | |
| 1atn | ATP | Actin, alpha skeletal muscle | / | 0.457 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.457 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.457 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.457 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.457 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 2e4n | SAH | Diphthine synthase | / | 0.456 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3w0n | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.456 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.456 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.455 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1w49 | APC | NTPase P4 | / | 0.455 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.455 | |
| 2i4u | DJR | Protease | / | 0.455 | |
| 2pci | SAH | Diphthine synthase | / | 0.455 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.455 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.455 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.455 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.455 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.455 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.454 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.453 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.453 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.453 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2p6l | SAH | Diphthine synthase | / | 0.453 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1wng | SAH | Diphthine synthase | / | 0.452 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 2e8q | SAH | Diphthine synthase | / | 0.452 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.452 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.452 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.452 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.452 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.451 | |
| 2e8h | SAH | Diphthine synthase | / | 0.451 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.451 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.451 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.451 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.450 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.449 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2ixa | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.449 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.449 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.449 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.448 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.448 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.448 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2b8t | THM | Thymidine kinase | / | 0.448 | |
| 2dsg | SAH | Diphthine synthase | / | 0.448 | |
| 2en5 | SAH | Diphthine synthase | / | 0.448 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.448 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.448 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.448 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1nja | DCM | Thymidylate synthase | / | 0.447 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.447 | |
| 2eni | SAH | Diphthine synthase | / | 0.447 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.447 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.447 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.447 | |
| 3ov7 | ATP | CCA-adding enzyme | 2.7.7.72 | 0.447 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.447 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.447 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.446 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.446 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.446 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.446 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.446 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.446 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.446 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2ejz | SAH | Diphthine synthase | / | 0.445 | |
| 2el0 | SAH | Diphthine synthase | / | 0.445 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.445 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.445 | |
| 2p6i | SAH | Diphthine synthase | / | 0.445 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3lpf | Z77 | Beta-glucuronidase | 3.2.1.31 | 0.445 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.445 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.445 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.444 | |
| 1w4a | APC | NTPase P4 | / | 0.444 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2dek | SAH | Diphthine synthase | / | 0.444 | |
| 2fto | TMP | Thymidylate synthase | / | 0.444 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.444 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.444 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2zxu | DST | tRNA dimethylallyltransferase | 2.5.1.75 | 0.444 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.444 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.444 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.444 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.444 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.443 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.443 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.443 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.443 | |
| 3u9e | COA | Lmo1369 protein | / | 0.443 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.443 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2dxv | SAH | Diphthine synthase | / | 0.442 | |
| 2e8r | SAH | Diphthine synthase | / | 0.442 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.442 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.442 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.442 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.441 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.441 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.441 | |
| 2hux | SAH | Diphthine synthase | / | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.441 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.441 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.441 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bvb | AR6 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4xd1 | T3Q | Qdtf | / | 0.441 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.440 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.440 | |
| 2dxx | SAH | Diphthine synthase | / | 0.440 | |
| 2e16 | SAH | Diphthine synthase | / | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.440 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.440 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.440 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.440 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4die | C5P | Cytidylate kinase | / | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.440 | |
| 4xcz | FON | Qdtf | / | 0.440 | |
| 4yqf | GDP | Septin-9 | / | 0.440 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.440 |