sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 1.000 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.656 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.651 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.616 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.610 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.575 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.574 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.574 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.572 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.568 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.568 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.565 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.561 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.560 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.555 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.555 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.550 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.549 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.549 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.547 | |
| 4b6l | 9ZP | Serine/threonine-protein kinase PLK3 | 2.7.11.21 | 0.545 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.540 | |
| 2xnn | 430 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.536 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.532 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.531 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.531 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.530 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.529 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.529 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.528 | |
| 2xno | ED8 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.524 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.521 | |
| 4f0f | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.512 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.510 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.509 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.506 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.499 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.499 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.494 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.493 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.492 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.491 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.489 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.489 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.488 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.488 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.488 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.486 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.483 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.482 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.480 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.479 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.478 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.478 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.474 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.472 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.471 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.470 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.470 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.469 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.469 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 5dp2 | NAP | CurF | / | 0.468 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.467 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.467 | |
| 3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.466 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.465 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.465 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.465 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.465 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.465 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.464 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.464 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.463 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.463 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.462 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.462 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.462 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.462 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.461 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.461 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4ux6 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.461 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3lm1 | LEC | Agglutinin alpha chain | / | 0.460 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.460 | |
| 4iae | 1DX | Alr2278 protein | / | 0.460 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.460 | |
| 4uqs | INE | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.460 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.460 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.459 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.459 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4f1o | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.459 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.459 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.459 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.458 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.457 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.457 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.456 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.456 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.456 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.455 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.455 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.455 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.455 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.455 | |
| 2bxo | OPB | Serum albumin | / | 0.454 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.454 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.454 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.454 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.454 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.454 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.453 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 4iah | 1DX | Alr2278 protein | / | 0.453 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.453 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.452 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.452 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.452 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 1m8i | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.451 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.451 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.450 | |
| 1m8h | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.450 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.450 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.449 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.449 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.449 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.449 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.448 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.448 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3up3 | XCA | aceDAF-12 | / | 0.448 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.448 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1t57 | FMN | Conserved protein | / | 0.447 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 4c4o | NAD | SADH | / | 0.447 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.447 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.446 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3hqd | ANP | Kinesin-like protein KIF11 | / | 0.446 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.446 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.445 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2ejz | SAH | Diphthine synthase | / | 0.445 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.445 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.445 | |
| 3b9l | AZZ | Serum albumin | / | 0.445 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1syn | F89 | Thymidylate synthase | / | 0.444 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2pir | DHT | Androgen receptor | / | 0.444 | |
| 2xvv | 9DN | Serum albumin | / | 0.444 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.444 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.444 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.444 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.444 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4lwb | QJ8 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.444 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.443 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.443 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3jq9 | AX1 | Pteridine reductase, putative | / | 0.443 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.443 | |
| 4qrc | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.442 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.442 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.442 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2yhu | WHF | Pteridine reductase | / | 0.442 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.442 | |
| 3pe1 | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.442 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.442 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.441 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.441 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.441 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.441 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.441 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.441 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.440 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1qiw | DPD | Calmodulin | / | 0.440 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.440 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.440 | |
| 2xvw | 9NR | Serum albumin | / | 0.440 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3jqg | AX6 | Pteridine reductase, putative | / | 0.440 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 |