sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pdc | 393 | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 1.000 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.696 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.688 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.686 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.679 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.674 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.653 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.650 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.649 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.649 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.648 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.646 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.641 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.640 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.640 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.638 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.637 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.635 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.630 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.629 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.628 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.628 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.627 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.627 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.626 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.626 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.626 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.626 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.625 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.625 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.625 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.625 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.622 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.620 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.619 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.616 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.615 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.615 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.614 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.614 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.611 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.609 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.603 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.601 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.595 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.591 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.586 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.563 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.561 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.561 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.556 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.538 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.524 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.516 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.516 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.507 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.507 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.501 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.498 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.494 | |
| 4phl | PIL | Phosphodiesterase | / | 0.492 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.489 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.488 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.487 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.486 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.485 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.485 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.484 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.479 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.479 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.478 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.478 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.477 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.476 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.476 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.475 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.474 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.473 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.473 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.472 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.472 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.471 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.469 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.469 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.469 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.467 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.467 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.466 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.466 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.466 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 3p9t | TCL | Repressor | / | 0.466 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.466 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.465 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.465 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.465 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.463 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4kxj | P34 | Nucleoprotein | / | 0.463 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.459 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 3c1o | NAP | Eugenol synthase | / | 0.459 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.459 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.458 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.458 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.458 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.458 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.458 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.457 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.457 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3ndj | JHZ | Methyltransferase | / | 0.457 | |
| 4e32 | DWN | Methyltransferase | / | 0.457 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.456 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.456 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.456 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.455 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.455 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1s36 | CEI | Obelin | / | 0.454 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.454 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.454 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.453 | |
| 4msk | 2C8 | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 1hqt | NAP | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.451 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.451 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.451 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 4xp1 | LDP | Sodium-dependent dopamine transporter | / | 0.451 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.450 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.450 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.450 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.449 | |
| 2jf6 | S55 | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.449 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.449 | |
| 4kmz | FOL | Folate receptor beta | / | 0.449 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.448 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.448 | |
| 1lke | DOG | Bilin-binding protein | / | 0.447 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1rxj | BNI | Streptavidin | / | 0.447 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.447 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.447 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.447 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.446 | |
| 1qv0 | CZH | Obelin | / | 0.446 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 2p1o | NLA | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.446 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.446 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3h7u | NAP | NADPH-dependent aldo-keto reductase, chloroplastic | / | 0.446 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.445 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.445 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.445 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.444 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.444 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.443 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 1e2l | TMC | Thymidine kinase | / | 0.442 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.442 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.442 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.441 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.440 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.440 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.440 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.440 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 |