sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 | 1.000 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.535 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.535 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.535 | |
| 1dth | BAT | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.527 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.522 | |
| 3kek | 3EK | Collagenase 3 | 3.4.24 | 0.519 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.517 | |
| 2w13 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.515 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.514 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.513 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.509 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.503 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.503 | |
| 1atl | 0QI | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.502 | |
| 2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.502 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.502 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.502 | |
| 2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.501 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.496 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.495 | |
| 4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.495 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.492 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.489 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.489 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.489 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.488 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.488 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.487 | |
| 3lik | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.487 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.487 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.487 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.485 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.485 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.484 | |
| 3k4y | IPE | Isopentenyl phosphate kinase | 2.7.4.26 | 0.484 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.482 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.479 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.479 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.479 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.478 | |
| 1iy8 | NAD | Levodione reductase | / | 0.478 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.477 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.477 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.477 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.476 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.476 | |
| 4gr0 | R4B | Macrophage metalloelastase | 3.4.24.65 | 0.476 | |
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 0.475 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.475 | |
| 3lgp | 50X | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.475 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.474 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.474 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.474 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.472 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.472 | |
| 2oy2 | ILE_ALA_GLY | Neutrophil collagenase | 3.4.24.34 | 0.471 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.471 | |
| 4lhv | GDP | Ras-related protein Rab-8A | / | 0.471 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.470 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.469 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.469 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.469 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.468 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.468 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.468 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.467 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.467 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.466 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.466 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.466 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.465 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.464 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.464 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.463 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.463 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.462 | |
| 2i47 | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.462 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.462 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.461 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.461 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4hxy | NDP | Plm1 | / | 0.461 | |
| 4tm4 | FDA | KtzI | / | 0.461 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.460 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.460 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.459 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3l0t | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.458 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.457 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.457 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.457 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.456 | |
| 2ble | 5GP | GMP reductase 1 | / | 0.456 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.456 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.456 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.456 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.455 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.455 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.455 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.455 | |
| 1cg4 | IMO | Adenylosuccinate synthetase | / | 0.454 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.453 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.453 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.453 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.453 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.452 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.452 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.452 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.452 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.451 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.451 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.451 | |
| 3c1o | NAP | Eugenol synthase | / | 0.451 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.451 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2srt | INH | Stromelysin-1 | 3.4.24.17 | 0.450 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.450 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.450 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.449 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.449 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3mje | NDP | AmphB | / | 0.449 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.449 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2bwp | PLG | 5-aminolevulinate synthase | 2.3.1.37 | 0.448 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.448 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.448 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.447 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.447 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.447 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.446 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.446 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.446 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.446 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.445 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.445 | |
| 1you | PFD | Collagenase 3 | 3.4.24 | 0.445 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.445 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.445 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.445 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.444 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.444 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.444 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.444 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.444 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.444 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.444 | |
| 3wag | TYD | Glycosyltransferase | / | 0.444 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.444 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 4hlk | 431 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4l0o | PLP | Cystathionine gamma-synthase | 2.5.1.48 | 0.444 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.443 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.443 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.443 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.443 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.443 | |
| 3q8h | AO9 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.443 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.443 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.443 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.443 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1gqt | ACP | Ribokinase | / | 0.442 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ves | GVR | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.442 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.442 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.442 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.442 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.442 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.442 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.441 | |
| 2ahc | VNL | Chorismate pyruvate-lyase | / | 0.441 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.441 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.441 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.441 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 1bxd | ANP | Osmolarity sensor protein EnvZ | 2.7.13.3 | 0.440 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.440 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2e4n | SAH | Diphthine synthase | / | 0.440 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.440 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.440 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.440 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.440 | |
| 4nvk | 2NY | Peroxidase | / | 0.440 |