sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 1.000 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.665 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.659 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.641 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.621 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.613 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.592 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.591 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.591 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.589 | |
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.587 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.586 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.582 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.580 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.579 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.576 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.566 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.564 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.563 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.561 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.561 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.561 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.560 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.557 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.555 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.555 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.552 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.549 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.545 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.544 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.541 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.536 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.521 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.500 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.493 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.490 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.490 | |
| 1qin | GIP | Lactoylglutathione lyase | 4.4.1.5 | 0.489 | |
| 4boe | CLR | Japanin | / | 0.489 | |
| 4n1g | CEI | Obelin | / | 0.488 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.486 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.481 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.479 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 2r0n | TGC | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.478 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.478 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.477 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.477 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.476 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.476 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.475 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.475 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.474 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.472 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.472 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.472 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 2k62 | ITL | Fatty acid-binding protein, liver | / | 0.471 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.471 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.471 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.470 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.469 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.469 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.469 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.469 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.469 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.469 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.468 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.468 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.467 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.467 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.466 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 4e2w | JHZ | Methyltransferase | / | 0.466 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.466 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.466 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.465 | |
| 1jf0 | CZH | Obelin | / | 0.465 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.465 | |
| 1rxj | BNI | Streptavidin | / | 0.465 | |
| 4e32 | DWN | Methyltransferase | / | 0.465 | |
| 4zas | TYD | CalS13 | / | 0.465 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.464 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.464 | |
| 4nqg | CZH | Mitrocomin | / | 0.464 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.462 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.462 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.462 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.461 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.461 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.461 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.461 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.461 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.460 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.460 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.460 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.460 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.459 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.459 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.459 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.458 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.458 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.458 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.457 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.457 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.457 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.457 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.456 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.456 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.455 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.455 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.455 | |
| 4rel | KMP | Glycosyltransferase | / | 0.455 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.455 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.454 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.454 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.453 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.453 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1s36 | CEI | Obelin | / | 0.452 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.452 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.452 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.452 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.451 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.451 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.451 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.451 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.451 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.451 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.450 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.450 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.450 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.450 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4e31 | JHZ | Methyltransferase | / | 0.450 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 1el4 | CTZ | Obelin | / | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.449 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.449 | |
| 2glr | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.449 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.449 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.449 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.448 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.448 | |
| 3c1o | NAP | Eugenol synthase | / | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3fuf | BES | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.448 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.448 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.448 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.448 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.448 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.448 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.448 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.448 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.448 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3vax | PLP | Uncharacterized protein | / | 0.447 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.447 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.446 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.446 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.446 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.446 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.446 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.446 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.445 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.445 | |
| 1lke | DOG | Bilin-binding protein | / | 0.445 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.445 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.445 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.445 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.445 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4iah | 1DX | Alr2278 protein | / | 0.445 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.444 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.444 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.444 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.444 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.443 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.443 | |
| 3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.443 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.443 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.443 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.443 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2e8w | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.442 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.442 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4iae | 1DX | Alr2278 protein | / | 0.442 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.442 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.442 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.441 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.441 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.441 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.441 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 3uel | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.441 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.441 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.441 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.440 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.440 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.440 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.440 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.440 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.440 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.440 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 |