sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 1.000 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.557 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.525 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.490 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.488 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.487 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.486 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.485 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.481 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.480 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.479 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.478 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.477 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.477 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.477 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.477 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4iae | 1DX | Alr2278 protein | / | 0.476 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.475 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.474 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.472 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.472 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.471 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.469 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.468 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.467 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.466 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.466 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.466 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.465 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.465 | |
| 4iah | 1DX | Alr2278 protein | / | 0.465 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.465 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.464 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.464 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.464 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.463 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.463 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.462 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.462 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.461 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.461 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.460 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.459 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.459 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.459 | |
| 1eio | GCH | Gastrotropin | / | 0.458 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.458 | |
| 2pnu | ENM | Androgen receptor | / | 0.458 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.458 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.458 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.458 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.458 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.457 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.457 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.457 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.457 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.456 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.456 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3e6e | DCS | Alanine racemase | / | 0.456 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.456 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.456 | |
| 1c7o | PPG | Hemolysin | / | 0.455 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3pn1 | IVH | DNA ligase | / | 0.455 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.455 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.454 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.454 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.454 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3v2u | ATP | Protein GAL3 | / | 0.454 | |
| 4e2z | JHZ | Methyltransferase | / | 0.454 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.454 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.453 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.453 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.453 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.453 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.452 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.452 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.452 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.452 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.452 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.452 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.452 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 1dtp | APU | Diphtheria toxin | / | 0.451 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.451 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.451 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.451 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.451 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.450 | |
| 1ddt | APU | Diphtheria toxin | / | 0.450 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.450 | |
| 1gm9 | SOX | Penicillin G acylase | 3.5.1.11 | 0.450 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.450 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.450 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.450 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.449 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.449 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.449 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.449 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3qp8 | HL0 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.449 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.449 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.449 | |
| 1wua | AP8 | Actin, alpha skeletal muscle | / | 0.448 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.448 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.448 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.448 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.447 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.447 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.447 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.447 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.447 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.446 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.446 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.446 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1ppj | ANY | Cytochrome b | / | 0.445 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.445 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.444 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.444 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.444 | |
| 4nqg | CZH | Mitrocomin | / | 0.444 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.443 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.443 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.442 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.442 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1el4 | CTZ | Obelin | / | 0.441 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.441 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.441 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.441 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.441 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.440 | |
| 2nr4 | FMN | Conserved protein | / | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.440 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.440 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.440 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.440 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 |