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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.21.000
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.654
5dt0SKEAurora kinase A2.7.11.10.552
4ivc1J6Tyrosine-protein kinase JAK1/0.532
2b7aIZATyrosine-protein kinase JAK2/0.519
4k6z1Q3Tyrosine-protein kinase JAK1/0.515
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.510
4ivb1J5Tyrosine-protein kinase JAK1/0.510
4ei40Q2Tyrosine-protein kinase JAK1/0.509
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.508
2q59240Peroxisome proliferator-activated receptor gamma/0.504
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.504
4hge15VTyrosine-protein kinase JAK2/0.501
4fx360KCyclin-dependent kinase 22.7.11.220.500
5dpvSKEAurora kinase A2.7.11.10.499
5dr9SKEAurora kinase A2.7.11.10.499
4ivd15TTyrosine-protein kinase JAK1/0.498
3eyhIZATyrosine-protein kinase JAK1/0.497
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.495
4e4l0NHTyrosine-protein kinase JAK1/0.494
4qmpDKISerine/threonine-protein kinase 242.7.11.10.491
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.487
4qmySTUSerine/threonine-protein kinase 242.7.11.10.487
3zmmF9JTyrosine-protein kinase JAK2/0.486
4ehzJAKTyrosine-protein kinase JAK1/0.486
3gu83GUDeath-associated protein kinase 12.7.11.10.485
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.485
1pxmCK5Cyclin-dependent kinase 22.7.11.220.484
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.484
2jkoBIJFocal adhesion kinase 12.7.10.20.483
3iok1P6Tyrosine-protein kinase JAK2/0.482
3rvg17PTyrosine-protein kinase JAK2/0.482
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
2x6dX6DAurora kinase A2.7.11.10.481
3r6xX84Cyclin-dependent kinase 22.7.11.220.481
4aqc88ATyrosine-protein kinase JAK2/0.481
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.480
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.480
4i5cC5ITyrosine-protein kinase JAK1/0.480
1m2rMNYCasein kinase II subunit alpha2.7.11.10.478
2wotZZGTGF-beta receptor type-12.7.11.300.478
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.478
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.477
2d8aNADL-threonine 3-dehydrogenase/0.477
2bkzSBCCyclin-dependent kinase 22.7.11.220.476
2i40BLZCyclin-dependent kinase 22.7.11.220.476
2w1eL0EAurora kinase A2.7.11.10.476
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.476
4acm7YGCyclin-dependent kinase 22.7.11.220.476
3rk909ZCyclin-dependent kinase 22.7.11.220.475
2jkqVG8Focal adhesion kinase 12.7.10.20.474
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.474
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.474
3ral04ZCyclin-dependent kinase 22.7.11.220.474
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.473
2dcnADP2-keto-3-deoxy-gluconate kinase/0.472
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.472
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3p7nFMNLight-activated DNA-binding protein EL222/0.472
4bgh3I6Cyclin-dependent kinase 22.7.11.220.472
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.472
4bbfO19Tyrosine-protein kinase JAK2/0.471
1urwI1PCyclin-dependent kinase 22.7.11.220.470
2w06FRVCyclin-dependent kinase 22.7.11.220.470
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.470
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.469
2pvnP63Casein kinase II subunit alpha2.7.11.10.469
3sw418KCyclin-dependent kinase 22.7.11.220.469
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.469
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.469
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.468
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.468
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.468
4f081RSTyrosine-protein kinase JAK2/0.468
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.468
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.468
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.467
1om1IQACasein kinase II subunit alpha2.7.11.10.467
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.467
4dgnLU2Casein kinase II subunit alpha2.7.11.10.467
4e5w0NTTyrosine-protein kinase JAK1/0.467
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.467
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.467
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.466
2rc3NADCBS domain/0.466
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.466
3ik6HCZGlutamate receptor 2/0.466
4fkv61KCyclin-dependent kinase 22.7.11.220.466
2dwbANPAurora kinase A2.7.11.10.465
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.465
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.465
3qqhX0ACyclin-dependent kinase 22.7.11.220.465
3s1h56ZCyclin-dependent kinase 22.7.11.220.465
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
5dosATPAurora kinase A2.7.11.10.465
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.464
2xb7GUIALK tyrosine kinase receptor2.7.10.10.464
2xikJ60Serine/threonine-protein kinase 252.7.11.10.464
3ggfGVDSerine/threonine-protein kinase 26/0.464
3roy22ZCyclin-dependent kinase 22.7.11.220.464
3s0o50ZCyclin-dependent kinase 22.7.11.220.464
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.464
3rpv26ZCyclin-dependent kinase 22.7.11.220.463
3sheI85MAP kinase-activated protein kinase 32.7.11.10.463
3zep1NXTyrosine-protein kinase JAK32.7.10.20.463
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.462
3raiX85Cyclin-dependent kinase 22.7.11.220.462
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.462
4jr7GNPCasein kinase II subunit alpha2.7.11.10.462
4lfiGNPCasein kinase II subunit alpha2.7.11.10.462
5dr6SKEAurora kinase A2.7.11.10.462
5j23A2RPutative 2-hydroxyacid dehydrogenase/0.462
1h1r6CPCyclin-dependent kinase 22.7.11.220.461
1p2a5BNCyclin-dependent kinase 22.7.11.220.461
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.461
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.461
2iw84SPCyclin-dependent kinase 22.7.11.220.461
2r3lSCWCyclin-dependent kinase 22.7.11.220.461
3qtrX36Cyclin-dependent kinase 22.7.11.220.461
3slkNDPPolyketide synthase extender module 2/0.461
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.461
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.461
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.460
3a62STURibosomal protein S6 kinase beta-12.7.11.10.460
3qu0X40Cyclin-dependent kinase 22.7.11.220.460
3rmf20ZCyclin-dependent kinase 22.7.11.220.460
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.460
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.460
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1zeoC01Peroxisome proliferator-activated receptor gamma/0.459
2jkkBI9Focal adhesion kinase 12.7.10.20.459
2wxvWXVCyclin-dependent kinase 22.7.11.220.459
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3mtfA3FActivin receptor type-12.7.11.300.459
3qwjX6ACyclin-dependent kinase 22.7.11.220.459
4k771Q4Tyrosine-protein kinase JAK1/0.459
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
5dn3ATPAurora kinase A2.7.11.10.459
1k74544Peroxisome proliferator-activated receptor gamma/0.458
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.458
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.458
2np8CC3Aurora kinase A2.7.11.10.458
3el9DR7Gag-Pol polyprotein3.4.23.160.458
3qqkX02Cyclin-dependent kinase 22.7.11.220.458
3qxpX64Cyclin-dependent kinase 22.7.11.220.458
1gih1PUCyclin-dependent kinase 22.7.11.220.457
3at3ATKCasein kinase II subunit alpha2.7.11.10.457
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.457
4e6q0NVTyrosine-protein kinase JAK2/0.457
4fk60UJTyrosine-protein kinase JAK1/0.457
4fkw62KCyclin-dependent kinase 22.7.11.220.457
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.457
5e8ySTUTGF-beta receptor type-22.7.11.300.457
1dm2HMDCyclin-dependent kinase 22.7.11.220.456
2c6o4SPCyclin-dependent kinase 22.7.11.220.456
2w1fL0FAurora kinase A2.7.11.10.456
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.456
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.456
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
1aq1STUCyclin-dependent kinase 22.7.11.220.455
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.455
2p4yC03Peroxisome proliferator-activated receptor gamma/0.455
2w1hL0FCyclin-dependent kinase 22.7.11.220.455
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.455
3p3zP3ZPutative cytochrome P450/0.455
3rak03ZCyclin-dependent kinase 22.7.11.220.455
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.455
4deeADPAurora kinase A2.7.11.10.455
4e5yNDPGDP-L-fucose synthase1.1.1.2710.455
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.455
4jbiNDPAlcohol dehydrogenase (Zinc)/0.455
2c6iDT1Cyclin-dependent kinase 22.7.11.220.454
2izsBRQCasein kinase I isoform gamma-32.7.11.10.454
2r3kSCQCyclin-dependent kinase 22.7.11.220.454
3mnrSD1Heat shock protein HSP 90-alpha/0.454
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4c62XWWTyrosine-protein kinase JAK2/0.454
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.454
4i22IREEpidermal growth factor receptor2.7.10.10.454
5cnnANPEpidermal growth factor receptor2.7.10.10.454
5e92ANPTGF-beta receptor type-22.7.11.300.454
1xjdSTUProtein kinase C theta type2.7.11.130.453
2c6tDT5Cyclin-dependent kinase 22.7.11.220.453
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.453
3dogNNNCyclin-dependent kinase 22.7.11.220.453
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.453
4eon1ROCyclin-dependent kinase 22.7.11.220.453
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.453
1e1xNW1Cyclin-dependent kinase 22.7.11.220.452
1oguST8Cyclin-dependent kinase 22.7.11.220.452
1pkdUCNCyclin-dependent kinase 22.7.11.220.452
1py5PY1TGF-beta receptor type-12.7.11.300.452
2c69CT8Cyclin-dependent kinase 22.7.11.220.452
2w05FRTCyclin-dependent kinase 22.7.11.220.452
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.452
3qtuX44Cyclin-dependent kinase 22.7.11.220.452
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.452
4c3rACPAurora kinase A2.7.11.10.452
4eor4SPCyclin-dependent kinase 22.7.11.220.452
4erwSTUCyclin-dependent kinase 22.7.11.220.452
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.452
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.452
1v1k3FPCyclin-dependent kinase 22.7.11.220.451
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.451
3wowANPCasein kinase II subunit alpha2.7.11.10.451
4aosFADSteroid monooxygenase/0.451
4fkr45KCyclin-dependent kinase 22.7.11.220.451
4hvi19STyrosine-protein kinase JAK32.7.10.20.451
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.451
4nxvGDPMitochondrial dynamics protein MID51/0.451
1di8DTQCyclin-dependent kinase 22.7.11.220.450
1g5sI17Cyclin-dependent kinase 22.7.11.220.450
1h1s4SPCyclin-dependent kinase 22.7.11.220.450
1i3mUD1UDP-glucose 4-epimerase/0.450
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.450
2dteNAIGlucose 1-dehydrogenase related protein/0.450
2r3r6SCCyclin-dependent kinase 22.7.11.220.450
2xa4AZ5Tyrosine-protein kinase JAK2/0.450
2zb3NDPProstaglandin reductase 21.3.1.480.450
3ormAGSSerine/threonine protein kinase/0.450
3rkb12ZCyclin-dependent kinase 22.7.11.220.450
3v9v21LPeroxisome proliferator-activated receptor gamma/0.450
4ewhT77Activated CDC42 kinase 1/0.450
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.450
1bwsNDPGDP-L-fucose synthase/0.449
1qp8NDP2-hydroxyacid dehydrogenase/0.449
1w0xOLOCyclin-dependent kinase 22.7.11.220.449
2henADPEphrin type-B receptor 22.7.10.10.449
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.449
2xmyCDKCyclin-dependent kinase 22.7.11.220.449
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
3u4cNDPNADPH-dependent reductase BacG/0.449
4ap1FADSteroid monooxygenase/0.449
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.449
5awmANPStress-activated protein kinase JNK2.7.11.240.449
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.449
1oiuN76Cyclin-dependent kinase 22.7.11.220.448
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
2p33J07Mitogen-activated protein kinase 102.7.11.240.448
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.448
2w1gL0GAurora kinase A2.7.11.10.448
2xrwANPMitogen-activated protein kinase 82.7.11.240.448
2xvu9DNSerum albumin/0.448
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4e6d0NUTyrosine-protein kinase JAK2/0.448
4gmy0X5Tyrosine-protein kinase JAK2/0.448
4hvh19RTyrosine-protein kinase JAK32.7.10.20.448
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.448
4o0wADNAurora kinase A2.7.11.10.448
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.447
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.447
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.447
3bheBZNGag-Pol polyprotein3.4.23.160.447
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.447
3kvxFMYMitogen-activated protein kinase 102.7.11.240.447
3mqe416Prostaglandin G/H synthase 21.14.99.10.447
3qtzX42Cyclin-dependent kinase 22.7.11.220.447
3qzgX67Cyclin-dependent kinase 22.7.11.220.447
3r9hZ67Cyclin-dependent kinase 22.7.11.220.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
4foc0UUALK tyrosine kinase receptor2.7.10.10.447
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.447
4gk4L90Ephrin type-A receptor 32.7.10.10.447
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.447
4zohFADPutative oxidoreductase FAD-binding subunit/0.447
5e8wSTUTGF-beta receptor type-12.7.11.300.447
1adfTADAlcohol dehydrogenase E chain1.1.1.10.446
1ipeNDPTropinone reductase 21.1.1.2360.446
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.446
2bhhRYUCyclin-dependent kinase 22.7.11.220.446
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.446
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.446
3nwq2NCGag-Pol polyprotein3.4.23.160.446
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3rk507ZCyclin-dependent kinase 22.7.11.220.446
3uzp0CKCasein kinase I isoform delta2.7.11.10.446
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.446
4gk2L66Ephrin type-A receptor 32.7.10.10.446
5aaaVGHALK tyrosine kinase receptor2.7.10.10.446
1unlRRCCyclin-dependent-like kinase 52.7.11.10.445
1zz2B11Mitogen-activated protein kinase 14/0.445
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.445
3at4CCKCasein kinase II subunit alpha2.7.11.10.445
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.445
3cyxROCGag-Pol polyprotein3.4.23.160.445
3el4ROCGag-Pol polyprotein3.4.23.160.445
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.445
4iwd1JCHepatocyte growth factor receptor2.7.10.10.445
5dnrATPAurora kinase A2.7.11.10.445
1bygSTUTyrosine-protein kinase CSK/0.444
1ckpPVBCyclin-dependent kinase 22.7.11.220.444
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.444
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.444
2iw94SPCyclin-dependent kinase 22.7.11.220.444
2uzlC94Cyclin-dependent kinase 22.7.11.220.444
3ddpRC8Cyclin-dependent kinase 22.7.11.220.444
3slz3TLPutative gag-pro-pol polyprotein/0.444
3wbfNAPMeso-diaminopimelate D-dehydrogenase/0.444
4bgg844Activin receptor type-12.7.11.300.444
4hgt15GCasein kinase I isoform delta2.7.11.10.444
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.444
4jboWPHAurora kinase A2.7.11.10.444
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.444
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.443
1y4lSVRBasic phospholipase A2 homolog 2/0.443
2b53D23Cyclin-dependent kinase 22.7.11.220.443
2e48FADD-amino-acid oxidase1.4.3.30.443
2eufLQQCyclin-dependent kinase 62.7.11.220.443
2uzdC85Cyclin-dependent kinase 22.7.11.220.443
2v7a627Tyrosine-protein kinase ABL12.7.10.20.443
2vgoAD5Aurora kinase B-A2.7.11.10.443
2w17I19Cyclin-dependent kinase 22.7.11.220.443
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
2xngA0HAurora kinase A2.7.11.10.443
2zjwREFCasein kinase II subunit alpha2.7.11.10.443
3bbrBHYGlutamate receptor 2/0.443
3rjc06ZCyclin-dependent kinase 22.7.11.220.443
3rk708ZCyclin-dependent kinase 22.7.11.220.443
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.443
3w32W32Epidermal growth factor receptor2.7.10.10.443
3w33W19Epidermal growth factor receptor2.7.10.10.443
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.443
4gub0Y4Casein kinase II subunit alpha2.7.11.10.443
4jajXU1Aurora kinase A2.7.11.10.443
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1t7j478Gag-Pol polyprotein3.4.23.160.442
1u4dDBQActivated CDC42 kinase 1/0.442
1vjy460TGF-beta receptor type-12.7.11.300.442
1zys199Serine/threonine-protein kinase Chk12.7.11.10.442
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.442
2yy7NADL-threonine dehydrogenase/0.442
3ad9NADSubunit alpha of sarocosine oxidase/0.442
3rni21ZCyclin-dependent kinase 22.7.11.220.442
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.442
3t8vBTJM1 family aminopeptidase3.4.110.442
3zdu38RCyclin-dependent kinase-like 32.7.11.220.442
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.442
4f07FADStyrene monooxygenase component 2/0.442
4jazSTLPeroxisome proliferator-activated receptor gamma/0.442
4o701QKBromodomain-containing protein 4/0.442
4q71FADBifunctional protein PutA/0.442
4xlvACPInsulin receptor2.7.10.10.442
1fm9570Peroxisome proliferator-activated receptor gamma/0.441
1oitHDTCyclin-dependent kinase 22.7.11.220.441
2r3o2SCCyclin-dependent kinase 22.7.11.220.441
2w9hTOPDihydrofolate reductase1.5.1.30.441
3g6wGTPUracil phosphoribosyltransferase2.4.2.90.441
3i60E86Mitogen-activated protein kinase 12.7.11.240.441
3jziJZLBiotin carboxylase6.3.4.140.441
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.441
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4eol1ROCyclin-dependent kinase 22.7.11.220.441
4fkpLS5Cyclin-dependent kinase 22.7.11.220.441
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.441
4kcfAKMFAD-dependent oxidoreductase/0.441
4yryFADGlutamate synthase, beta subunit/0.441
2a0cCK9Cyclin-dependent kinase 22.7.11.220.440
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.440
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.440
3gubGUBDeath-associated protein kinase 12.7.11.10.440
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.440
3s2pPMUCyclin-dependent kinase 22.7.11.220.440
3sdkP3NProteasome subunit beta type-53.4.25.10.440
3sdkP3NProteasome subunit beta type-63.4.25.10.440
3stw2TDMethylketone synthase I/0.440
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.440
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.440
4aotGW8Serine/threonine-protein kinase 102.7.11.10.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4brxKGWFocal adhesion kinase 12.7.10.20.440
4btjADPTau-tubulin kinase 12.7.11.10.440
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.440
4i8vBHFCytochrome P450 1A11.14.14.10.440
4wsqKSAAP2-associated protein kinase 12.7.11.10.440
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440