sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3hl7 | I47 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.648 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.633 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.621 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.617 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.607 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.603 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.599 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.598 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.598 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.581 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.580 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.579 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.578 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.573 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.568 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.567 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.567 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.565 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.561 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.559 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.555 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.555 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.549 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.545 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.543 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.542 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.541 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.541 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.540 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.539 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.539 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.535 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.532 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.531 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.526 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.522 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.522 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.519 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.508 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.505 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.497 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.497 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.497 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.496 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.492 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.488 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.488 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.487 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.486 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.485 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.485 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.485 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.483 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.483 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.482 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.482 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.481 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 4ih8 | B43 | Calmodulin-domain protein kinase 1 | / | 0.480 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.480 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.479 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.479 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.478 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.478 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.475 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.475 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.474 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.474 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.474 | |
| 4mxa | BK7 | Calmodulin-like domain protein kinase isoenzyme gamma, related | / | 0.474 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.473 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.473 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.472 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.472 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.472 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.472 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.470 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.470 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.469 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.469 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.468 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.468 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.468 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.468 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.468 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.468 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.468 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.467 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.467 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.467 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.466 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.466 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.465 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.465 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.465 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.464 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.464 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.464 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.464 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.463 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.463 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.463 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.463 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.463 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.463 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.463 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.462 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.462 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.462 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.461 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.461 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.460 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.460 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.460 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.459 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.458 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.458 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.458 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.457 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.457 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
| 3fc1 | 52P | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2bqv | A1A | Protease | / | 0.456 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.456 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.455 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.455 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.455 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.454 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.454 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.454 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.454 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.453 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.453 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.453 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.452 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.452 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.452 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.452 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.452 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 2xb7 | GUI | ALK tyrosine kinase receptor | 2.7.10.1 | 0.451 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.451 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2uzn | C96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.450 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.450 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.450 | |
| 4erk | OLO | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.450 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.449 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.449 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.449 | |
| 2b54 | D05 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2fgi | PD1 | Fibroblast growth factor receptor 1 | / | 0.449 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.449 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.449 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.449 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 3zuy | TCH | Transporter | / | 0.449 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.449 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.449 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.448 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.448 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.448 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.448 | |
| 3gob | HXX | DdmC | / | 0.448 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.448 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.447 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.447 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.447 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.447 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.447 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.447 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.447 | |
| 4nfn | 2KC | Tau-tubulin kinase 1 | 2.7.11.1 | 0.447 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.447 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.447 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.446 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.446 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.445 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.445 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2w4i | VGA | Glutamate racemase | / | 0.445 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.445 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.444 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.444 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4c61 | LMM | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4qmu | SKE | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
| 1r78 | FMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.443 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.443 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.443 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.443 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.443 | |
| 3qai | XNN | Ketohexokinase | / | 0.443 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4jlt | 8PR | Cytochrome P450 2B4 | 1.14.14.1 | 0.443 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.443 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.443 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.442 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.442 | |
| 2fum | MIX | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.442 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.442 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.442 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.442 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.442 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.442 | |
| 4fz6 | 0VG | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4i0r | 1B4 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.441 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 2qkr | IXM | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.441 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 3iw7 | IPK | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 4f9w | LM4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.441 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.440 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.440 | |
| 3nbv | ANP | Ketohexokinase | / | 0.440 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.440 | |
| 3u9e | COA | Lmo1369 protein | / | 0.440 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.440 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.440 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.440 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 |