sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3b28 | B2X | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.748 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.651 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.633 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.615 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.614 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.599 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.598 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.596 | |
| 1qy5 | NEC | Endoplasmin | / | 0.591 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.591 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.590 | |
| 1ysz | NEC | Endoplasmin | / | 0.589 | |
| 1u0z | RDC | Endoplasmin | / | 0.585 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.576 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.572 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.568 | |
| 1qy8 | RDI | Endoplasmin | / | 0.565 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.563 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.561 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.554 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.552 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.550 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.549 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.548 | |
| 1u0y | PA7 | Endoplasmin | / | 0.546 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.540 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.539 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.538 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.536 | |
| 2gfd | RDA | Endoplasmin | / | 0.536 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.535 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.534 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 2hch | N5A | Endoplasmin | / | 0.531 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.530 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 2hg1 | N5O | Endoplasmin | / | 0.529 | |
| 2gqp | PA7 | Endoplasmin | / | 0.527 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.526 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 1u2o | NEC | Endoplasmin | / | 0.523 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 3ied | AN2 | HSP90 | / | 0.522 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.519 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.519 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.508 | |
| 2fyp | RDE | Endoplasmin | / | 0.508 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.507 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.506 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.504 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.498 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.497 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.496 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.496 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.495 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.493 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.492 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.490 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.487 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.486 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.484 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.483 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.482 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.481 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.480 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.477 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.474 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.473 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.472 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.468 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.468 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.467 | |
| 2o1u | ANP | Endoplasmin | / | 0.467 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.467 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.467 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.463 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.463 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.462 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.461 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.461 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.460 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.460 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.459 | |
| 3a6r | FMN | FMN-binding protein | / | 0.459 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.459 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.459 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.459 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.459 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2exl | GDM | Endoplasmin | / | 0.458 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.458 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.458 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3a20 | FMN | FMN-binding protein | / | 0.456 | |
| 3bva | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.455 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.455 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.455 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.454 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.454 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.454 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.453 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.453 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.452 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.452 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.452 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 3so9 | 017 | Pol protein | / | 0.452 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.451 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.451 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.451 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.451 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.451 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.451 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.451 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.451 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.451 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.450 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 2e07 | SAH | Diphthine synthase | / | 0.450 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.450 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.450 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.450 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.450 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.449 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.449 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.448 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.447 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1ohh | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.447 | |
| 1ohh | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.447 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.447 | |
| 1vce | SAH | Diphthine synthase | / | 0.447 | |
| 1yt0 | ADP | Endoplasmin | / | 0.447 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.447 | |
| 2emr | SAH | Diphthine synthase | / | 0.447 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.447 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.447 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.447 | |
| 4dja | FAD | (6-4) photolyase | / | 0.447 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.447 | |
| 4jic | FMN | GTN Reductase | / | 0.447 | |
| 1a8g | 2Z4 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.446 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.446 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.446 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.446 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.446 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.445 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.445 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.445 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.444 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.444 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4die | C5P | Cytidylate kinase | / | 0.444 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.443 | |
| 2nmy | ROC | Protease | / | 0.443 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.442 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.442 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.442 | |
| 2e7r | SAH | Diphthine synthase | / | 0.442 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.442 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.442 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.442 | |
| 3dck | KVI | Protease | / | 0.442 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 4jal | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.442 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.441 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.441 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.441 | |
| 2nnp | ROC | Protease | / | 0.441 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.441 | |
| 2p3b | 3TL | V-1 protease | / | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 3amf | FMN | FMN-binding protein | / | 0.441 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.441 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4i5v | B4P | Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2 | / | 0.441 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.440 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.440 | |
| 2o1v | ADP | Endoplasmin | / | 0.440 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.440 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.440 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |