sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xht | C0Y | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.654 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.613 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.609 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.607 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.600 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.596 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.594 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.593 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.586 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.586 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.586 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.585 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.583 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.582 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.582 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.582 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.580 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.580 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.579 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.572 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.571 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.571 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.568 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.566 | |
| 1ysz | NEC | Endoplasmin | / | 0.563 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.562 | |
| 2o1u | ANP | Endoplasmin | / | 0.561 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.560 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.559 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.557 | |
| 1u0z | RDC | Endoplasmin | / | 0.555 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.553 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.546 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.540 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.539 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.539 | |
| 2hg1 | N5O | Endoplasmin | / | 0.538 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.537 | |
| 1u2o | NEC | Endoplasmin | / | 0.537 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.536 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 2gfd | RDA | Endoplasmin | / | 0.530 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.530 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.527 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.526 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.526 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 2o1v | ADP | Endoplasmin | / | 0.523 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.521 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.519 | |
| 2gqp | PA7 | Endoplasmin | / | 0.518 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 3ied | AN2 | HSP90 | / | 0.517 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.514 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.513 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2hch | N5A | Endoplasmin | / | 0.513 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.511 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.511 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.509 | |
| 2esa | GDM | Endoplasmin | / | 0.507 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.505 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.503 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.499 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.498 | |
| 1u0y | PA7 | Endoplasmin | / | 0.495 | |
| 1yt0 | ADP | Endoplasmin | / | 0.495 | |
| 2exl | GDM | Endoplasmin | / | 0.495 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.495 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.495 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.493 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 1qy5 | NEC | Endoplasmin | / | 0.492 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.491 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.487 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.482 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.480 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.478 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.478 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.477 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.476 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.476 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.475 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 2bu2 | ATP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.473 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.470 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2hkj | RDC | Type 2 DNA topoisomerase 6 subunit B | / | 0.467 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.467 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.466 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.464 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.463 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.462 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.462 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4yau | 2AM | NADPH--cytochrome P450 reductase | / | 0.462 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 2wi2 | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.461 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.460 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.460 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.460 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.460 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.458 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.457 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.457 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.457 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.456 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.456 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.456 | |
| 2ye9 | 2D4 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.453 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.452 | |
| 2yi7 | BZ8 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.452 | |
| 4ksh | HTT | DNA gyrase subunit B | / | 0.452 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.452 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.451 | |
| 2cct | 2E1 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.450 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4egn | TWO | Cytochrome P450 | / | 0.449 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.448 | |
| 3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4e4l | 0NH | Tyrosine-protein kinase JAK1 | / | 0.448 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.447 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 3b9l | AZZ | Serum albumin | / | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.447 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.447 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.447 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 4ku3 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.446 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.445 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.445 | |
| 3dol | GWI | Pol protein | / | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.444 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 4b6c | B5U | DNA gyrase subunit B | / | 0.444 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 5d3f | FSC | 14-3-3 protein zeta/delta | / | 0.443 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.442 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.442 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.442 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.442 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.441 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.441 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.441 | |
| 4oae | CLM | Uncharacterized protein | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.440 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.440 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3ft5 | MO8 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3u9e | COA | Lmo1369 protein | / | 0.440 | |
| 5a3b | APR | SIR2 family protein | / | 0.440 |