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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2wuuNHWGlycylpeptide N-tetradecanoyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2wuuNHWGlycylpeptide N-tetradecanoyltransferase/1.000
5a28MYAGlycylpeptide N-tetradecanoyltransferase/0.683
4c68NHWGlycylpeptide N-tetradecanoyltransferase/0.679
5ag7MYAGlycylpeptide N-tetradecanoyltransferase/0.673
5ag5MYAGlycylpeptide N-tetradecanoyltransferase/0.672
2yncYNCGlycylpeptide N-tetradecanoyltransferase/0.669
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.662
4cgpMYAGlycylpeptide N-tetradecanoyltransferase/0.661
4a30MYAGlycylpeptide N-tetradecanoyltransferase/0.649
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.649
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.644
5ag6MYAGlycylpeptide N-tetradecanoyltransferase/0.643
4b13NHWGlycylpeptide N-tetradecanoyltransferase/0.642
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.641
4b10NHWGlycylpeptide N-tetradecanoyltransferase/0.640
4b12NHWGlycylpeptide N-tetradecanoyltransferase/0.640
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.639
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.638
2wsaMYAGlycylpeptide N-tetradecanoyltransferase/0.634
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.634
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.632
2yneNHWGlycylpeptide N-tetradecanoyltransferase/0.629
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.627
4b11NHWGlycylpeptide N-tetradecanoyltransferase/0.623
4c2zMYAGlycylpeptide N-tetradecanoyltransferase 1/0.623
4b14NHWGlycylpeptide N-tetradecanoyltransferase/0.611
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.597
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.588
4qbjNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.568
4j6dTESCytochrome P450 monooxygenase/0.519
2yjxYJXHeat shock protein HSP 90-alpha/0.506
5bp9SAHPutative methyltransferase protein/0.506
5a3cNADSIR2 family protein/0.504
4uymVOR14-alpha sterol demethylase Cyp51B/0.503
4iarERM5-hydroxytryptamine receptor 1B/0.502
4j6cSTRCytochrome P450 monooxygenase/0.502
2ykeYKEHeat shock protein HSP 90-alpha/0.499
3tdaPN0Cytochrome P450 2D6/0.499
2ykbYKBHeat shock protein HSP 90-alpha/0.497
1pqc444Oxysterols receptor LXR-beta/0.494
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.494
2ykjYKJHeat shock protein HSP 90-alpha/0.493
1re9DSOCamphor 5-monooxygenase1.14.15.10.491
5dp2NAPCurF/0.491
5jtbZMAAdenosine receptor A2a/0.490
3a1l2CCCytochrome P450/0.489
4iaq2GM5-hydroxytryptamine receptor 1B/0.488
4at0FADPossible succinate dehydrogenase/0.487
2ykcYKCHeat shock protein HSP 90-alpha/0.486
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.486
4j6bPLOCytochrome P450 monooxygenase/0.486
3nx4NAPPutative oxidoreductase/0.485
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.484
4jqh1MFAlr2278 protein/0.484
1h36R88Squalene--hopene cyclase4.2.1.1290.483
2q9fC3SCholesterol 24-hydroxylase/0.483
3qm4PN0Cytochrome P450 2D6/0.482
4do30LAFatty-acid amide hydrolase 13.5.1.990.482
5k2cZMAAdenosine receptor A2a/0.482
3p6oETGCamphor 5-monooxygenase1.14.15.10.481
1xddAAYIntegrin alpha-L/0.480
3abaFLICytochrome P450/0.480
3p6pA6BCamphor 5-monooxygenase1.14.15.10.480
4jbtASDCytochrome P450 monooxygenase/0.480
2j9lATPH(+)/Cl(-) exchange transporter 5/0.479
2z3uCRRCytochrome P450/0.479
4o7uTHFThymidylate synthase/0.479
5k2aZMAAdenosine receptor A2a/0.479
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.478
2fwyH64Heat shock protein HSP 90-alpha/0.478
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.477
3reyXACAdenosine receptor A2a/0.477
3p6nDSOCamphor 5-monooxygenase1.14.15.10.476
4id5T27Gag-Pol polyprotein2.7.7.490.476
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.476
1ci7CB3Thymidylate synthase2.1.1.450.475
2x23TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.475
1uyePU9Heat shock protein HSP 90-alpha/0.474
2ykiYKIHeat shock protein HSP 90-alpha/0.474
4tm3FADKtzI/0.474
2zb8IMNProstaglandin reductase 21.3.1.480.473
3jynNDPQuinone oxidoreductase/0.473
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.473
1opbRETRetinol-binding protein 2/0.472
2g78REACellular retinoic acid-binding protein 2/0.472
3is9AC7Gag-Pol polyprotein2.7.7.490.472
3ol5SAWCamphor 5-monooxygenase1.14.15.10.472
1tysDHFThymidylate synthase/0.471
1uydPU8Heat shock protein HSP 90-alpha/0.471
4nieNBHNuclear receptor ROR-gamma/0.471
5a3bAPRSIR2 family protein/0.471
5dozNDPJamJ/0.471
1hb1OCVIsopenicillin N synthase1.21.3.10.470
3mnrSD1Heat shock protein HSP 90-alpha/0.470
3p6mDSOCamphor 5-monooxygenase1.14.15.10.470
4pd6URINucleoside permease/0.470
1uy9PU6Heat shock protein HSP 90-alpha/0.469
2ylwFADPhenylacetone monooxygenase1.14.13.920.469
4b4vL34Bifunctional protein FolD/0.469
4i8vBHFCytochrome P450 1A11.14.14.10.469
4isk1JYThymidylate synthase/0.469
3pwhZMAAdenosine receptor A2a/0.469
1disBDMDihydrofolate reductase1.5.1.30.468
1diuBDMDihydrofolate reductase1.5.1.30.468
1uy6PU3Heat shock protein HSP 90-alpha/0.468
3s1dZIRCytokinin dehydrogenase 11.5.99.120.468
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.468
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.468
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.468
1hb3SCVIsopenicillin N synthase1.21.3.10.467
2dvlFADAcyl-CoA dehydrogenase/0.467
3gw9VNILanosterol 14-alpha-demethylase/0.467
3vt7VDXVitamin D3 receptor/0.467
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.467
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.467
4wriOKAOkadaic acid binding protein 2-alpha/0.467
1ep4S11Gag-Pol polyprotein2.7.7.490.466
1ie8KH1Vitamin D3 receptor/0.466
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.466
3up4NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.466
4hy6FJ1Heat shock protein HSP 90-alpha/0.466
1uyfPU1Heat shock protein HSP 90-alpha/0.465
2rjp886A disintegrin and metalloproteinase with thrombospondin motifs 43.4.24.820.465
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.465
4iae1DXAlr2278 protein/0.465
4nh82LCHeat shock protein HSP 90-alpha/0.465
1cbsREACellular retinoic acid-binding protein 2/0.464
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
2ftoCB3Thymidylate synthase/0.464
2i9pNAD3-hydroxyisobutyrate dehydrogenase, mitochondrial1.1.1.310.464
4foxD16Thymidylate synthase ThyA/0.464
1trgCB3Thymidylate synthase/0.463
2rm2W43Genome polyprotein/0.463
3vt5YI2Vitamin D3 receptor/0.463
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4ifvT27Gag-Pol polyprotein2.7.7.490.463
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.463
5k2bZMAAdenosine receptor A2a/0.463
5k2dZMAAdenosine receptor A2a/0.463
1cc2FADCholesterol oxidase1.1.3.60.462
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2bxnIDBSerum albumin/0.462
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.462
2qg2A91Heat shock protein HSP 90-alpha/0.462
3bhlTHGThymidylate synthase/0.462
3up0D7SaceDAF-12/0.462
4h4o506Gag-Pol polyprotein2.7.7.490.462
1ezfIN0Squalene synthase2.5.1.210.461
2c7xNRBCytochrome P450 monooxygenase PikC/0.461
3t8xT8XT-cell surface glycoprotein CD1b/0.461
1bk0ACVIsopenicillin N synthase1.21.3.10.460
1ie9VDXVitamin D3 receptor/0.460
1jolFFODihydrofolate reductase1.5.1.30.460
1uykPUXHeat shock protein HSP 90-alpha/0.460
2c0cNAPProstaglandin reductase 310.460
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.460
3bgrT27Gag-Pol polyprotein2.7.7.490.460
3e5aVX6Aurora kinase A2.7.11.10.460
3hz5Z64Heat shock protein HSP 90-alpha/0.460
3l0lHC3Nuclear receptor ROR-gamma/0.460
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.460
4elg52JDihydrofolate reductase/0.460
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.460
1kzjCB3Thymidylate synthase/0.459
1q5dEPBEpothilone C/D epoxidase1.140.459
1uymPU3Heat shock protein HSP 90-beta/0.459
2p15EZTEstrogen receptor/0.459
2po7CHDFerrochelatase, mitochondrial4.99.1.10.459
2w4qCBWProstaglandin reductase 21.3.1.480.459
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.459
2y05NAPProstaglandin reductase 1/0.459
4i2pG73Gag-Pol polyprotein2.7.7.490.459
4ia2BIVVitamin D3 receptor A/0.459
4ktf1TMCytochrome P450/0.459
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
2h55DZ8Heat shock protein HSP 90-alpha/0.458
2ym1FADPhenylacetone monooxygenase1.14.13.920.458
3iaeD7KBenzaldehyde lyase/0.458
3sfi3SFHTH-type transcriptional regulator EthR/0.458
3w0aDS5Vitamin D3 receptor/0.458
4fweFADLysine-specific histone demethylase 1B10.458
1mp0NADAlcohol dehydrogenase class-31.1.1.10.457
1qiqACCIsopenicillin N synthase1.21.3.10.457
1tduCB3Thymidylate synthase/0.457
2yk2YJXHeat shock protein HSP 90-alpha/0.457
3p99LNPLanosterol 14-alpha-demethylase/0.457
3v94WYQPhosphodiesterase/0.457
3qakUKAAdenosine receptor A2a/0.457
1dajMOTDihydrofolate reductase1.5.1.30.456
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.456
1n83CLRNuclear receptor ROR-alpha/0.456
2hcdBIVVitamin D3 receptor A/0.456
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.456
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.456
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4qe6JN3Bile acid receptor/0.456
4rv9SAHD-mycarose 3-C-methyltransferase/0.456
1h35R01Squalene--hopene cyclase4.2.1.1290.455
1mxtFAECholesterol oxidase1.1.3.60.455
1upw444Oxysterols receptor LXR-beta/0.455
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
1yb5NAPQuinone oxidoreductase1.6.5.50.455
2fzwNADAlcohol dehydrogenase class-31.1.1.10.455
2iviACWIsopenicillin N synthase1.21.3.10.455
2rc4ACOHistone acetyltransferase KAT6A/0.455
2zd1T27Gag-Pol polyprotein2.7.7.490.455
3cxhSMACytochrome b/0.455
3hu3AGSTransitional endoplasmic reticulum ATPase3.6.4.60.455
3kpkFADSulfide-quinone reductase/0.455
3mlaJJZProbable nicotinate-nucleotide adenylyltransferase/0.455
3o3nIRC(R)-2-hydroxyisocaproyl-CoA dehydratase alpha subunit/0.455
3w2cN15Aurora kinase A2.7.11.10.455
4ez8DHFThymidylate synthase2.1.1.450.455
4mfpCOAUncharacterized protein/0.455
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.455
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.455
5fm7ADPRuvB-like helicase/0.455
1fwmCB3Thymidylate synthase/0.454
1xdkREARetinoic acid receptor beta/0.454
2aazCB3Thymidylate synthase2.1.1.450.454
2ol4JPNEnoyl-ACP reductase/0.454
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.454
3hz137DHeat shock protein HSP 90-alpha/0.454
3slkNDPPolyketide synthase extender module 2/0.454
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.454
3t2yFADSulfide-quinone reductase/0.454
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.454
4gl4NAIAlcohol dehydrogenase class-3/0.454
4iah1DXAlr2278 protein/0.454
4j4vSVRNucleocapsid protein/0.454
1p8dCO1Oxysterols receptor LXR-beta/0.453
2fwzH71Heat shock protein HSP 90-alpha/0.453
2ylxFADPhenylacetone monooxygenase1.14.13.920.453
3inxJZCHeat shock protein HSP 90-alpha/0.453
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.453
3vt9YI4Vitamin D3 receptor/0.453
4iq71G9Mycocyclosin synthase1.14.21.90.453
4o95245Cytokinin dehydrogenase 4/0.453
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.453
4rbs0RVMetallo-beta-lactamase type 2/0.453
1eioGCHGastrotropin/0.452
1zhwHC2Oxysterol-binding protein homolog 4/0.452
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.452
2jb4A14Isopenicillin N synthase1.21.3.10.452
2y6fM9FIsopenicillin N synthase1.21.3.10.452
3d7kD7KBenzaldehyde lyase/0.452
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3nduROCGag-Pol polyprotein3.4.23.160.452
4bqg50QHeat shock protein HSP 90-alpha/0.452
4d7eFADPutative lysine-N-oxygenase/0.452
5kf8ACOPredicted acetyltransferase/0.452
1b87ACOAac(6')-Ii protein/0.451
1hvyD16Thymidylate synthase2.1.1.450.451
1jg0DDTThymidylate synthase/0.451
1u0hONMAdenylate cyclase type 2/0.451
1u0hONMAdenylate cyclase type 5/0.451
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2d29FADAcyl-CoA dehydrogenase/0.451
2f3815MAldo-keto reductase family 1 member C3/0.451
2gpjFADSiderophore-interacting protein/0.451
2w1hL0FCyclin-dependent kinase 22.7.11.220.451
2yig5ELCollagenase 33.4.240.451
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.451
3cid318Beta-secretase 13.4.23.460.451
3crzFADFerredoxin--NADP+ reductase/0.451
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.451
4fxfATPPyruvate kinase PKM2.7.1.400.451
4oztP1AEcdysone receptor, putative/0.451
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.451
2xpuTDCTetracycline repressor protein class D/0.450
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3t14FADSulfide-quinone reductase/0.450
4ib4ERM5-hydroxytryptamine receptor 2B/0.450
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.450
3uzaT4GAdenosine receptor A2a/0.450
1g3mPCQEstrogen sulfotransferase2.8.2.40.449
1n4uFAECholesterol oxidase1.1.3.60.449
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.449
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.449
2zb3NDPProstaglandin reductase 21.3.1.480.449
3ipq965Oxysterols receptor LXR-alpha/0.449
3sf6FDAGlutaryl-CoA dehydrogenase/0.449
3tqhNDPQuinone oxidoreductase/0.449
4aotGW8Serine/threonine-protein kinase 102.7.11.10.449
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.449
4da0GNGPurine nucleoside phosphorylase DeoD-type2.4.2.10.449
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.449
4i2q1BTGag-Pol polyprotein2.7.7.490.449
4u2lSFDCholesterol oxidase1.1.3.60.449
5hs1VORLanosterol 14-alpha demethylase/0.449
5d5bCAUBeta-2 adrenergic receptor/0.449
1cbqRE9Cellular retinoic acid-binding protein 2/0.448
1hrvSDZGenome polyprotein/0.448
1kzuRG1Light-harvesting protein B-800/850 alpha chain/0.448
1kzuRG1Light-harvesting protein B-800/850 beta chain/0.448
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.448
1uyhPU0Heat shock protein HSP 90-alpha/0.448
1zq5E04Aldo-keto reductase family 1 member C3/0.448
2aclL05Oxysterols receptor LXR-alpha/0.448
2aibERGBeta-elicitin cinnamomin/0.448
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.448
2hasC3OVitamin D3 receptor/0.448
2hb7O1CVitamin D3 receptor/0.448
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.448
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.448
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
3ox4NADAlcohol dehydrogenase 21.1.1.10.448
3stv3HOMethylketone synthase I/0.448
3uyk0CXProbable NDP-rhamnosyltransferase/0.448
3w5rLOAVitamin D3 receptor/0.448
4b7xNAPProbable oxidoreductase/0.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.448
4c4oNADSADH/0.448
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.448
5ab6CAANonspecific lipid-transfer protein, putative/0.448
5kf2ACOPredicted acetyltransferase/0.448
1fd0254Retinoic acid receptor gamma/0.447
1khrCOAStreptogramin A acetyltransferase2.3.10.447
1nq7ARLNuclear receptor ROR-beta/0.447
1osvCHCBile acid receptor/0.447
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.447
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.447
2fzhDH1Dihydrofolate reductase1.5.1.30.447
3bfa9ODOdorant binding protein ASP1/0.447
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3o6o94MHeat shock protein 83/0.447
3q44D50M1 family aminopeptidase3.4.110.447
3qdd94MHeat shock protein HSP 90-alpha/0.447
3tvuB37Acetyl-CoA carboxylase/0.447
3zos0LIEpithelial discoidin domain-containing receptor 12.7.10.10.447
4b4w9L9Bifunctional protein FolD/0.447
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.447
4itfTFYVitamin D3 receptor/0.447
4jlj1NMDeoxycytidine kinase2.7.1.740.447
4wx1FDAUDP-galactopyranose mutase/0.447
4z26FADPutative GMC-type oxidoreductase R13510.447
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.447
7catNDPCatalase1.11.1.60.447
1f4fTP3Thymidylate synthase/0.446
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.446
1tl7ONMAdenylate cyclase type 2/0.446
1tl7ONMAdenylate cyclase type 5/0.446
2qk8MTXDihydrofolate reductase/0.446
2vnaNAPProstaglandin reductase 21.3.1.480.446
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
2zynBCDPeriplasmic binding protein/0.446
3bi5FADPolyamine oxidase FMS1/0.446
3bqdDAYGlucocorticoid receptor/0.446
3ce31FNHepatocyte growth factor receptor2.7.10.10.446
3gkjHC3Niemann-Pick C1 protein/0.446
3ijdC2FMethylenetetrahydrofolate reductase/0.446
3livE16Protease/0.446
3ogqAB1Pol polyprotein/0.446
3pqbVGPPutative oxidoreductase/0.446
3wmxNADNAD dependent epimerase/dehydratase/0.446
4elf35IDihydrofolate reductase/0.446
4g1qT27Gag-Pol polyprotein2.7.7.490.446
4jlk1NODeoxycytidine kinase2.7.1.740.446
4qzuRTLRetinol-binding protein 2/0.446
1cf3FADGlucose oxidase1.1.3.40.445
1ffuFADCarbon monoxide dehydrogenase medium chain/0.445
1jq5NADGlycerol dehydrogenase1.1.1.60.445
1pq944BOxysterols receptor LXR-beta/0.445
1rf9DBRCamphor 5-monooxygenase1.14.15.10.445
1uy8PU5Heat shock protein HSP 90-alpha/0.445
1uzwCDHIsopenicillin N synthase1.21.3.10.445
1x8b824Wee1-like protein kinase2.7.10.20.445
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.445
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.445
2iutAGSDNA translocase FtsK/0.445
2om9AJAPeroxisome proliferator-activated receptor gamma/0.445
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.445
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.445
2ylrFADPhenylacetone monooxygenase1.14.13.920.445
2yltFADPhenylacetone monooxygenase1.14.13.920.445
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.445
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3zs5SB2Mitogen-activated protein kinase 14/0.445
4blcNDPCatalase1.11.1.60.445
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.445
4dm6TTBRetinoic acid receptor beta/0.445
4dw60MNHTH-type transcriptional regulator EthR/0.445
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.445
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4ips1G4Mycocyclosin synthase1.14.21.90.445
4ktkKTKCytochrome P450/0.445
4u2sFDACholesterol oxidase1.1.3.60.445
4zj8SUVOrexin receptor type 1/0.445
4z9g1Q5Corticotropin-releasing factor receptor 1/0.445
2fziDH3Dihydrofolate reductase1.5.1.30.444
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.444
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3nfaCBJGag-Pol polyprotein/0.444
3o9cK20Pol polyprotein/0.444
3oev3OEProteasome subunit beta type-53.4.25.10.444
3oev3OEProteasome subunit beta type-63.4.25.10.444
3qlhT27Gag-Pol polyprotein2.7.7.490.444
3tdl11DSerum albumin/0.444
3tmz06XCytochrome P450 2B41.14.14.10.444
3uwlFOZThymidylate synthase/0.444
3vt65YIVitamin D3 receptor/0.444
3w78CBDFMN-dependent NADH-azoreductase/0.444
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.444
4g3jVNTLanosterol 14-alpha-demethylase/0.444
4g95OAGDihydrofolate reductase1.5.1.30.444
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.444
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.443
1cjwCOTSerotonin N-acetyltransferase/0.443
1jlaTNKGag-Pol polyprotein2.7.7.490.443
1k2b0Q4Gag-Pol polyprotein3.4.23.160.443
1o6rR19Squalene--hopene cyclase4.2.1.1290.443
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.443
1ppjANYCytochrome b/0.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
2braFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.443
2hm9TRRDihydrofolate reductase1.5.1.30.443
2iogIOGEstrogen receptor/0.443
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
2vf0F89Thymidylate synthase/0.443
2zlcVDXVitamin D3 receptor/0.443
3cbsR12Cellular retinoic acid-binding protein 2/0.443
3cndFADPolyamine oxidase FMS1/0.443
3h1jSMACytochrome b/0.443
3hjkFADVivid PAS protein VVD/0.443
3l6jZ90Alr2278 protein/0.443
3tguWF3Cytochrome b/0.443
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.443
3w0c6DSVitamin D3 receptor/0.443
4ele31IDihydrofolate reductase/0.443
4k4eK4ETankyrase-12.4.2.300.443
4ktl1CQCytochrome P450/0.443
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.443
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
4qjqOTRLactoperoxidase/0.443
3rfmCFFAdenosine receptor A2a/0.443
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.442
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
2pk5075Protease/0.442
2q61SF1Peroxisome proliferator-activated receptor gamma/0.442
2qjpSMACytochrome b/0.442
2rr1W8RGenome polyprotein/0.442
2uxuNARHTH-type transcriptional regulator TtgR/0.442
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3fowIMHPurine nucleoside phosphorylase/0.442
3inwJZBHeat shock protein HSP 90-alpha/0.442
3rpnGTXGlutathione S-transferase kappa 12.5.1.180.442
3ukkFADUDP-galactopyranose mutase/0.442
4eiyZMAAdenosine receptor A2a/0.442
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.442
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
5irnADPNucleotide binding oligomerization domain containing 2/0.442
1aypINBPhospholipase A2, membrane associated/0.441
1c6yMK1Protease/0.441
1iyzNDPProbable quinone oxidoreductase/0.441
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
1kt3RTLRetinol-binding protein 4/0.441
1kt4RTLRetinol-binding protein 4/0.441
1y9dTPPPyruvate oxidase1.2.3.30.441
1zhzERGOxysterol-binding protein homolog 4/0.441
2bjsACVIsopenicillin N synthase1.21.3.10.441
2pmoHMDProtein kinase 7/0.441
2qe0NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase1.2.1.90.441
2qi0MZ3Gag-Pol polyprotein/0.441
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.441
2rs1W84Genome polyprotein/0.441
2uxhQUEHTH-type transcriptional regulator TtgR/0.441
3d74NBBPheromone-binding protein ASP1/0.441
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3ibdCPZCytochrome P450 2B61.14.130.441
3l8p0CEAngiopoietin-1 receptor2.7.10.10.441
3q0uLL3HTH-type transcriptional regulator EthR/0.441
3qwbNDPProbable quinone oxidoreductase1.6.5.50.441
3u1y03IUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.441
3up3XCAaceDAF-12/0.441
3vt45YIVitamin D3 receptor/0.441
3w8wFADPutative FAD-dependent oxygenase EncM/0.441
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4a6cQG9Gag-Pol polyprotein3.4.23.160.441
4bfpSWYTankyrase-22.4.2.300.441
4bvnP32Beta-1 adrenergic receptor/0.441
4ia3BIVVitamin D3 receptor A/0.441
4kfbT27Gag-Pol polyprotein2.7.7.490.441
5g53NECAdenosine receptor A2a/0.441
4uhrNGIAdenosine receptor A2a/0.441
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1jx0DFVChalcone--flavonone isomerase 15.5.1.60.440
1sqbAZOCytochrome b/0.440
1ztq033Collagenase 33.4.240.440
2dw4FADLysine-specific histone demethylase 1A10.440
2fhjMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.440
2ibuCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.440
2o3zAI7UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.440
2ze2T27Gag-Pol polyprotein2.7.7.490.440
3ad9NADSubunit alpha of sarocosine oxidase/0.440
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.440
3lu8IQXSerum albumin/0.440
3o8gO8GHTH-type transcriptional regulator EthR/0.440
3vqsJT1Genome polyprotein/0.440
3vs1VSATyrosine-protein kinase HCK2.7.10.20.440
3vt8YI3Vitamin D3 receptor/0.440
3w33W19Epidermal growth factor receptor2.7.10.10.440
3zkyWT4Isopenicillin N synthase1.21.3.10.440
4c77N01Phenylacetone monooxygenase1.14.13.920.440
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4fv6E57Mitogen-activated protein kinase 12.7.11.240.440
4g1z0VPVitamin D3 receptor A/0.440
4pyoSAHCatechol O-methyltransferase2.1.1.60.440
4qgiROCGag-Pol polyprotein3.4.23.160.440
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.440