Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2v7u | SAM | 5'-fluoro-5'-deoxy-adenosine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2v7u | SAM | 5'-fluoro-5'-deoxy-adenosine synthase | / | 1.000 | |
| 2v7t | SAH | 5'-fluoro-5'-deoxy-adenosine synthase | / | 0.806 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.526 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.520 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.511 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.507 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.507 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.497 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.493 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.492 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.487 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.487 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.487 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.486 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.485 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.483 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.483 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.480 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.479 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.479 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.478 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.478 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.478 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.475 | |
| 1azl | FMN | Flavodoxin | / | 0.474 | |
| 1fx1 | FMN | Flavodoxin | / | 0.474 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.474 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.474 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.473 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.473 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.472 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.469 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.469 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.468 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.468 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.468 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.468 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.466 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.466 | |
| 4jxr | ACO | Acetyltransferase | / | 0.466 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.465 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.465 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.464 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.464 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.464 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.464 | |
| 4e32 | DWN | Methyltransferase | / | 0.464 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.464 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.463 | |
| 3hgg | CHD | CmeR | / | 0.463 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.463 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.463 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.463 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.462 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.462 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.461 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.461 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.461 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.460 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.460 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.459 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.459 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.459 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 3arv | SAU | Chitinase A | / | 0.458 | |
| 1c3r | TSN | Acetoin utilization protein | / | 0.457 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.457 | |
| 2r5n | TPP | Transketolase 1 | / | 0.457 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.457 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.456 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.456 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.456 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.456 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.456 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.456 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.456 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.456 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.456 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.456 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.455 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.455 | |
| 4bzb | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.455 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.455 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.454 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.454 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.454 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.454 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4y0k | NAP | AntE | / | 0.454 | |
| 1gm9 | SOX | Penicillin G acylase | 3.5.1.11 | 0.453 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.453 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.453 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.453 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.453 | |
| 4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.453 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.453 | |
| 2ejz | SAH | Diphthine synthase | / | 0.452 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.452 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.452 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.452 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.452 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.451 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.451 | |
| 3csj | CBL | Glutathione S-transferase P | 2.5.1.18 | 0.451 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.451 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.451 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.451 | |
| 4kxj | P34 | Nucleoprotein | / | 0.451 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.450 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.450 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.450 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.450 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.450 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.450 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.450 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.450 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.450 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.449 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.449 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.449 | |
| 2v5u | FMN | Flavodoxin | / | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3b9g | IMH | IAG-nucleoside hydrolase | / | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.449 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.449 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.449 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.448 | |
| 1xi2 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.448 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.448 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.448 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.448 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.448 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.448 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 4j7g | TRH | PCZA361.3 | / | 0.448 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.448 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.448 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.448 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.447 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 3b3f | SAH | Histone-arginine methyltransferase CARM1 | / | 0.447 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.447 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.447 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.447 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4fou | C2E | Uncharacterized protein | / | 0.447 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1j8q | FMN | Flavodoxin | / | 0.446 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.446 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.446 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.446 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.446 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2oat | PFM | Ornithine aminotransferase, mitochondrial | 2.6.1.13 | 0.446 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.446 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.446 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.446 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.445 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.445 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.445 | |
| 3c1o | NAP | Eugenol synthase | / | 0.445 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.445 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.445 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.445 | |
| 4j7h | TRH | PCZA361.3 | / | 0.445 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.444 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.444 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1wkg | POI | [LysW]-aminoadipate semialdehyde transaminase | / | 0.444 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.444 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2npf | MOU | Elongation factor 2 | / | 0.444 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.444 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3e78 | TPP | High affinity transport system protein p37 | / | 0.444 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.444 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.444 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.444 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.444 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.444 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.444 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.443 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.443 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.443 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.443 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3eks | CY9 | Actin-5C | / | 0.443 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.443 | |
| 3frk | TQP | QdtB | / | 0.443 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.443 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.443 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.443 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.443 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.442 | |
| 2o3u | NGD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.442 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.442 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.442 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.442 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.441 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1njj | ORX | Ornithine decarboxylase | / | 0.441 | |
| 2e07 | SAH | Diphthine synthase | / | 0.441 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.441 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.441 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.441 | |
| 4d2c | ALA_PHE | Di-or tripeptide:H+ symporter | / | 0.441 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.441 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.441 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.440 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.440 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1ye6 | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.440 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.440 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.440 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.440 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.440 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.440 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.440 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.440 | |
| 4to3 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.440 |