sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p5c | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2p5c | SAH | Diphthine synthase | / | 1.000 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.871 | |
| 2dxx | SAH | Diphthine synthase | / | 0.863 | |
| 2p5f | SAH | Diphthine synthase | / | 0.843 | |
| 2e7r | SAH | Diphthine synthase | / | 0.839 | |
| 2dsi | SAH | Diphthine synthase | / | 0.834 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.826 | |
| 2p6i | SAH | Diphthine synthase | / | 0.819 | |
| 2ejk | SAH | Diphthine synthase | / | 0.816 | |
| 2p6k | SAH | Diphthine synthase | / | 0.801 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.798 | |
| 2pck | SAH | Diphthine synthase | / | 0.796 | |
| 2owg | SAH | Diphthine synthase | / | 0.795 | |
| 2eni | SAH | Diphthine synthase | / | 0.791 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.786 | |
| 2p2x | SAH | Diphthine synthase | / | 0.786 | |
| 2egs | SAH | Diphthine synthase | / | 0.782 | |
| 2p9d | SAH | Diphthine synthase | / | 0.764 | |
| 2pcg | SAH | Diphthine synthase | / | 0.763 | |
| 2owk | SAH | Diphthine synthase | / | 0.760 | |
| 2hut | SAH | Diphthine synthase | / | 0.749 | |
| 2pch | SAH | Diphthine synthase | / | 0.745 | |
| 2dxv | SAH | Diphthine synthase | / | 0.743 | |
| 2dxw | SAH | Diphthine synthase | / | 0.743 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.740 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.730 | |
| 2eka | SAH | Diphthine synthase | / | 0.722 | |
| 2emr | SAH | Diphthine synthase | / | 0.719 | |
| 2el0 | SAH | Diphthine synthase | / | 0.715 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.713 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.711 | |
| 2huv | SAH | Diphthine synthase | / | 0.710 | |
| 2p6d | SAH | Diphthine synthase | / | 0.709 | |
| 2pca | SAH | Diphthine synthase | / | 0.709 | |
| 2eeq | SAH | Diphthine synthase | / | 0.706 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.702 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.699 | |
| 2huq | SAH | Diphthine synthase | / | 0.699 | |
| 2egb | SAH | Diphthine synthase | / | 0.697 | |
| 2ele | SAH | Diphthine synthase | / | 0.697 | |
| 2e08 | SAH | Diphthine synthase | / | 0.695 | |
| 2e15 | SAH | Diphthine synthase | / | 0.695 | |
| 1wng | SAH | Diphthine synthase | / | 0.694 | |
| 2dsg | SAH | Diphthine synthase | / | 0.692 | |
| 2ehl | SAH | Diphthine synthase | / | 0.689 | |
| 2owu | SAH | Diphthine synthase | / | 0.689 | |
| 2e8s | SAH | Diphthine synthase | / | 0.681 | |
| 2emu | SAH | Diphthine synthase | / | 0.673 | |
| 2dsh | SAH | Diphthine synthase | / | 0.672 | |
| 2e17 | SAH | Diphthine synthase | / | 0.672 | |
| 2pcm | SAH | Diphthine synthase | / | 0.672 | |
| 2e8r | SAH | Diphthine synthase | / | 0.664 | |
| 2eld | SAH | Diphthine synthase | / | 0.659 | |
| 2el3 | SAH | Diphthine synthase | / | 0.656 | |
| 2z6r | SAH | Diphthine synthase | / | 0.652 | |
| 1vce | SAH | Diphthine synthase | / | 0.651 | |
| 2hux | SAH | Diphthine synthase | / | 0.647 | |
| 2egl | SAH | Diphthine synthase | / | 0.644 | |
| 2ejj | SAH | Diphthine synthase | / | 0.644 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.644 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.644 | |
| 2e4n | SAH | Diphthine synthase | / | 0.642 | |
| 2e8q | SAH | Diphthine synthase | / | 0.641 | |
| 2e07 | SAH | Diphthine synthase | / | 0.634 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.631 | |
| 2pci | SAH | Diphthine synthase | / | 0.631 | |
| 2e8h | SAH | Diphthine synthase | / | 0.630 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.621 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.617 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.603 | |
| 2en5 | SAH | Diphthine synthase | / | 0.601 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.580 | |
| 2owf | SAH | Diphthine synthase | / | 0.579 | |
| 2owv | SAH | Diphthine synthase | / | 0.575 | |
| 2e16 | SAH | Diphthine synthase | / | 0.566 | |
| 2ejz | SAH | Diphthine synthase | / | 0.564 | |
| 2dek | SAH | Diphthine synthase | / | 0.535 | |
| 2p6l | SAH | Diphthine synthase | / | 0.510 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.499 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.489 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.488 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.485 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.480 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.476 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.475 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.474 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.471 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.470 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.468 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.468 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.468 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.466 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.465 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.463 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.463 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.461 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.460 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.459 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.459 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.459 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.458 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.458 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.458 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.458 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.457 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.457 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.457 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.457 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.457 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.456 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.456 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.456 | |
| 2y65 | ADP | Kinesin heavy chain | / | 0.456 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.456 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.456 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.456 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.455 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 3zuy | TCH | Transporter | / | 0.455 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.454 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.454 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.454 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.452 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.452 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.451 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.451 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.451 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.451 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.451 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.451 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.450 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.450 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.450 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.450 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.450 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.449 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.449 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.449 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.449 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.448 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.448 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.448 | |
| 2p3b | 3TL | V-1 protease | / | 0.448 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.448 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.447 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.447 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3so9 | 017 | Pol protein | / | 0.447 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.447 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.446 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.446 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.446 | |
| 3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.446 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.446 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.446 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.445 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.444 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.444 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.444 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.444 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.444 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.444 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.444 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.443 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.443 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.443 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.443 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.443 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.443 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.442 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.442 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a4q | UX9 | Pol protein | / | 0.442 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.442 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 4kb9 | G79 | Protease | / | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.442 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.441 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.441 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.441 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.441 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.440 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.440 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.440 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.440 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 |