sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1n0u | SO1 | Elongation factor 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1n0u | SO1 | Elongation factor 2 | / | 1.000 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.720 | |
| 2npf | MOU | Elongation factor 2 | / | 0.577 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.522 | |
| 1qjg | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.508 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.505 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.502 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.499 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.498 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.493 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.488 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.487 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.483 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.482 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.481 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.481 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.478 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.476 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.475 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.474 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4gda | BTN | Streptavidin | / | 0.474 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.474 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.474 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.474 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.472 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.472 | |
| 1lcw | SHM | Streptavidin | / | 0.471 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.471 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.471 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.471 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.471 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.470 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.470 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.470 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.470 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.469 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.469 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.468 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.468 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.468 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 2uyw | BTN | Avd protein | / | 0.467 | |
| 3ry2 | BTN | Streptavidin | / | 0.467 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.466 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.466 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.466 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.465 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.465 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.465 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.465 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.465 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.463 | |
| 2c4i | BTN | Avidin | / | 0.463 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.463 | |
| 2xvw | 9NR | Serum albumin | / | 0.463 | |
| 3arv | SAU | Chitinase A | / | 0.463 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.463 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.463 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.462 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.462 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.462 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.462 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.462 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.462 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.461 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.461 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.461 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.461 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.460 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.460 | |
| 1xh8 | R55 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 2ejz | SAH | Diphthine synthase | / | 0.460 | |
| 4n1g | CEI | Obelin | / | 0.460 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.460 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2izl | IMI | Streptavidin | / | 0.459 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.459 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.459 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.459 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4cb4 | MGT | Polymerase basic protein 2 | / | 0.459 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.459 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.458 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.458 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.458 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.458 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.458 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.457 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.457 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.457 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.457 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.457 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2rtn | IMI | Streptavidin | / | 0.457 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.457 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.457 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.456 | |
| 1fml | RTL | Retinol dehydratase | / | 0.456 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.456 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.456 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.456 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.456 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.455 | |
| 2rtf | BTN | Streptavidin | / | 0.455 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.455 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.455 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.455 | |
| 1q13 | TES | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.454 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.454 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.454 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.454 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.454 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.454 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.454 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.453 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.453 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 3b9l | AZZ | Serum albumin | / | 0.453 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.453 | |
| 3v2u | ATP | Protein GAL3 | / | 0.453 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.452 | |
| 3e8x | NAP | BH1520 protein | / | 0.452 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.452 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.452 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.451 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.450 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.450 | |
| 2izk | GLL | Streptavidin | / | 0.450 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.450 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.450 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.450 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.450 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.450 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.450 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.449 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 1stp | BTN | Streptavidin | / | 0.448 | |
| 1swt | BTN | Streptavidin | / | 0.448 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.448 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.448 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.448 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4boe | CLR | Japanin | / | 0.448 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.448 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.447 | |
| 1xj7 | DHT | Androgen receptor | / | 0.447 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.447 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3qgd | 23E | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.447 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.447 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.447 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.446 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.446 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.446 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 5epe | SAH | Uncharacterized protein | / | 0.446 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.445 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.445 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.445 | |
| 2izh | BTN | Streptavidin | / | 0.445 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.445 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.445 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2xvv | 9DN | Serum albumin | / | 0.445 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.445 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.445 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.445 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.445 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.445 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1sqi | 869 | 4-hydroxyphenylpyruvate dioxygenase | / | 0.444 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.444 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.444 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2acw | UPG | Glycosyltransferase | / | 0.443 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.443 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.443 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4iah | 1DX | Alr2278 protein | / | 0.443 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1i9h | BNI | Streptavidin | / | 0.442 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.442 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.442 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2rtd | BTN | Streptavidin | / | 0.442 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.442 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3vey | 0H5 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.442 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.442 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.442 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.442 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.442 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.441 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.441 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1vce | SAH | Diphthine synthase | / | 0.441 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.441 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.441 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.441 | |
| 2p1d | SAH | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 2pix | DHT | Androgen receptor | / | 0.441 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.441 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.441 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.441 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.441 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.441 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.440 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1sre | HAB | Streptavidin | / | 0.440 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.440 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.440 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2rtk | GLL | Streptavidin | / | 0.440 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.440 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 4hcy | 0YN | Transketolase | / | 0.440 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.440 |