sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ef3 | FID | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.645 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.644 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.636 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.614 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.614 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.613 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.612 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.610 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.610 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.607 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.601 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.594 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.591 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.590 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.570 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.567 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.560 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.552 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.550 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.539 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.536 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.528 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.526 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.525 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.523 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.523 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.515 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.511 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.509 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.509 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.509 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.507 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.506 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.506 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.502 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.501 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.499 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.499 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.496 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.495 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.494 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.493 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.493 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.490 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 1uhj | CZB | Aequorin-2 | / | 0.486 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.486 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.486 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.485 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.484 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.483 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.483 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.483 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.482 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.480 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.480 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.479 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.478 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.476 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.476 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.473 | |
| 2nvd | ITB | Aldose reductase | 1.1.1.21 | 0.473 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.473 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.473 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.471 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.471 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.471 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.470 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.469 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.469 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.469 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.468 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.468 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.468 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.467 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.466 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.466 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.466 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.465 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.465 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.465 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.465 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.465 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.465 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.464 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.464 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.464 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4nqg | CZH | Mitrocomin | / | 0.463 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.462 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.462 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.462 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.462 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.462 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.461 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.461 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.461 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.461 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.460 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.460 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.459 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.458 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.458 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.458 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.458 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 4j7g | TRH | PCZA361.3 | / | 0.458 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.457 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.457 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 1rxj | BNI | Streptavidin | / | 0.456 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.456 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.456 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.456 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.456 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.455 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.455 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.455 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.455 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.455 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.455 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.454 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.454 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.453 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.453 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.453 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.453 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.452 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.452 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.452 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.451 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.451 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.451 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.451 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.451 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2iuz | D1H | Endochitinase B1 | 3.2.1.14 | 0.450 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.449 | |
| 1qvt | PRL | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.449 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.449 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.448 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.448 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.448 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2r6k | GTX | Glutathione S-transferase A1 | 2.5.1.18 | 0.448 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3arv | SAU | Chitinase A | / | 0.448 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.448 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4nv0 | MG7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.448 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.448 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2hzq | STR | Apolipoprotein D | / | 0.446 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.446 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.446 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.446 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1s36 | CEI | Obelin | / | 0.445 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.445 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.445 | |
| 4l4v | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.445 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.445 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.445 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.444 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.444 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.444 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.444 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.443 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.443 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.443 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.443 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.443 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.442 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.442 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.442 | |
| 4dyb | 0MH | Nucleoprotein | / | 0.442 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 1el4 | CTZ | Obelin | / | 0.441 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2v7t | SAH | 5'-fluoro-5'-deoxy-adenosine synthase | / | 0.441 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.441 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.441 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.441 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.441 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.440 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.440 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3owx | XRA | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.440 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.440 |