sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.684 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.676 | |
| 3qly | 55V | Uncharacterized protein | / | 0.654 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.645 | |
| 3eem | 53V | Uncharacterized protein | / | 0.634 | |
| 3cse | N22 | Uncharacterized protein | / | 0.633 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.626 | |
| 3eej | 53R | Uncharacterized protein | / | 0.625 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.621 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.618 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.616 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.615 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.609 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.609 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.605 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.602 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.601 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.599 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.599 | |
| 3eek | 53S | Uncharacterized protein | / | 0.597 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.596 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.593 | |
| 3eel | 53T | Uncharacterized protein | / | 0.592 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.588 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.585 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.584 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.583 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.580 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.574 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.568 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.551 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.547 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.545 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.545 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.543 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.542 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.541 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.541 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.539 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.538 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.538 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.533 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.533 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.533 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.528 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.526 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.525 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.522 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.521 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.519 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.518 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.518 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.514 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.513 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.513 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.511 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.508 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.507 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.507 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.506 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.504 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.500 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.500 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.499 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.499 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.497 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.495 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.494 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.492 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.491 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.490 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.489 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.489 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.489 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.488 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.488 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.487 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.487 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.486 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.485 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.485 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.484 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.483 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.483 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.483 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.482 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.482 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.481 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.480 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.479 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.478 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.477 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.476 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.476 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.476 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.476 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.474 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.474 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.473 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.473 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.473 | |
| 3v49 | PK0 | Androgen receptor | / | 0.473 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.472 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.471 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.471 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.470 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.470 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.470 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.470 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.469 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.469 | |
| 3n62 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.469 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.469 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.469 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.468 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.468 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.468 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 | 0.467 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3h1j | SMA | Cytochrome b | / | 0.467 | |
| 3p9t | TCL | Repressor | / | 0.467 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.467 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.465 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.465 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.465 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.465 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.464 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.464 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.464 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.464 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.464 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.463 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.463 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.463 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.463 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.463 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.462 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.462 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.462 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.462 | |
| 4m7v | RAR | Dihydrofolate reductase | / | 0.462 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.461 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.461 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.461 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.460 | |
| 2xvv | 9DN | Serum albumin | / | 0.460 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.460 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.460 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.460 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.459 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.459 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.459 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.459 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.459 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.458 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.457 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.457 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.457 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.457 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.456 | |
| 1err | RAL | Estrogen receptor | / | 0.456 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2p15 | EZT | Estrogen receptor | / | 0.456 | |
| 2v5x | V5X | Histone deacetylase 8 | 3.5.1.98 | 0.456 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.456 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.456 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.456 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.456 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.456 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.456 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.456 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.455 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.455 | |
| 1jut | LYD | Thymidylate synthase | / | 0.455 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.455 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.455 | |
| 2pnu | ENM | Androgen receptor | / | 0.455 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.455 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.455 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.455 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.455 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.454 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.454 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.454 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.454 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.454 | |
| 1fml | RTL | Retinol dehydratase | / | 0.453 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.453 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.453 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.453 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 1axw | MTX | Thymidylate synthase | / | 0.452 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.452 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.452 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.452 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.451 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.451 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.451 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.451 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.451 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.451 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.451 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1yin | CM3 | Estrogen receptor | / | 0.450 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.450 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.450 | |
| 2xvw | 9NR | Serum albumin | / | 0.450 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.450 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.450 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.450 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.450 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.450 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.449 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.449 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.449 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.449 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.449 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.448 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.448 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.448 | |
| 4a2z | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.447 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1sqv | UHD | Cytochrome b | / | 0.447 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.447 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.447 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.447 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.447 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.447 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.447 | |
| 6cox | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2bx8 | AZQ | Serum albumin | / | 0.446 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.446 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3b9l | AZZ | Serum albumin | / | 0.446 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.446 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.446 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 4la0 | 198 | Serum albumin | / | 0.446 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.445 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.445 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.445 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.445 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.445 | |
| 2pmn | K51 | Protein kinase 7 | / | 0.445 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.445 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.445 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.445 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.445 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.445 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.445 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.444 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1yre | COA | Uncharacterized protein | / | 0.444 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.444 | |
| 2hvc | LGD | Androgen receptor | / | 0.444 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.444 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.444 | |
| 3aba | FLI | Cytochrome P450 | / | 0.444 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.444 | |
| 3v4a | PK1 | Androgen receptor | / | 0.444 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.444 | |
| 4cx3 | HW8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.444 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.444 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.443 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.443 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3bhr | THG | Thymidylate synthase | / | 0.443 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.443 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.443 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.443 | |
| 4egn | TWO | Cytochrome P450 | / | 0.443 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.443 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.442 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.442 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3bhl | THG | Thymidylate synthase | / | 0.442 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.442 | |
| 4o4f | ATP | Kinase | / | 0.442 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.441 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1syn | F89 | Thymidylate synthase | / | 0.441 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.441 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.441 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.441 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.441 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3pne | 8AX | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.441 | |
| 4cfl | 8DQ | Bromodomain-containing protein 4 | / | 0.441 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.441 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.441 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.440 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1e7a | PFL | Serum albumin | / | 0.440 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.440 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.440 | |
| 2wpw | ACO | Orf14 | / | 0.440 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.440 | |
| 2yat | EEU | Estrogen receptor | / | 0.440 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.440 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.440 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.440 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4k5g | Q13 | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.440 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.440 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 | |
| 4xwt | U5P | Ribonuclease J | / | 0.440 |