Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2v3a FAD Rubredoxin-NAD(+) reductase 1.18.1.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
2v3a FADRubredoxin-NAD(+) reductase 1.18.1.1 1.445
1d7y FADFerredoxin reductase / 0.875
3ef6 FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.868
2gqw FADFerredoxin reductase / 0.857
4h4x FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.848
2gr0 FADFerredoxin reductase / 0.843
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.842
4h4t FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.842
4h4z FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.828
4opi FDAConserved Archaeal protein / 0.827
1gv4 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.825
5c2t FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 0.820
4h4v FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.810
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.808
4bv6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.806
1f8w FADNADH peroxidase 1.11.1.1 0.804
5fs9 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.803
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.801
4h4r FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.801
2yvj FADFerredoxin reductase / 0.797
1q1r FADPutidaredoxin reductase 1.18.1.5 0.795
1q1w FADPutidaredoxin reductase 1.18.1.5 0.790
3gd3 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.788
3ic9 FADPutative dihydrolipoamide dehydrogenase / 0.785
3rp8 FADFAD-dependent urate hydroxylase / 0.782
4opg FDAConserved Archaeal protein / 0.778
5er0 FADUncharacterized NAD(FAD)-dependent dehydrogenase / 0.776
3axb FADPutative oxidoreductase / 0.763
2wp5 FADTrypanothione reductase / 0.761
1f3p FADFerredoxin reductase / 0.760
1trb FADThioredoxin reductase 1.8.1.9 0.758
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.757
3dk8 FADGlutathione reductase, mitochondrial 1.8.1.7 0.757
4opd FDAConserved Archaeal protein / 0.756
1dnc FADGlutathione reductase, mitochondrial 1.8.1.7 0.754
1get FADGlutathione reductase 1.8.1.7 0.754
2du8 FADD-amino-acid oxidase 1.4.3.3 0.753
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.751
2hqm FADGlutathione reductase 1.8.1.7 0.750
4h4y FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.748
3lb8 FADPutidaredoxin reductase 1.18.1.5 0.747
2npx FADNADH peroxidase 1.11.1.1 0.744
4k2x FADPolyketide oxygenase/hydroxylase / 0.744
4lii FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.744
1nhr FADNADH peroxidase 1.11.1.1 0.743
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.743
4h4u FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.742
4emw FADCoenzyme A disulfide reductase / 0.741
1zx9 FADMercuric reductase 1.16.1.1 0.740
4k5r FADOxygenase / 0.740
1mo9 FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.739
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.739
3nta FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.738
4bk2 FADProbable salicylate monooxygenase / 0.737
5fs6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.736
4emj FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.734
2gr3 FADFerredoxin reductase / 0.732
2wba FADTrypanothione reductase 1.8.1.12 0.732
3kpk FADSulfide-quinone reductase / 0.732
5fs8 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.732
1gsn FADGlutathione reductase, mitochondrial 1.8.1.7 0.731
1nhs FADNADH peroxidase 1.11.1.1 0.731
4h4q FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.731
2cdu FADNADH oxidase / 0.730
3dgz FADThioredoxin reductase 2, mitochondrial 1.8.1.9 0.730
1rsg FADPolyamine oxidase FMS1 / 0.728
3cuk FADD-amino-acid oxidase 1.4.3.3 0.728
4j57 FADThioredoxin reductase 2 1.8.1.9 0.728
3f8p NADNADH oxidase/thioredoxin reductase / 0.727
1kif FADD-amino-acid oxidase 1.4.3.3 0.726
5buk FADFADH2-dependent halogenase / 0.726
1ges FADGlutathione reductase 1.8.1.7 0.725
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.725
1zk7 FADMercuric reductase 1.16.1.1 0.721
3dk9 FADGlutathione reductase, mitochondrial 1.8.1.7 0.721
3ntd FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.721
1bwc FADGlutathione reductase, mitochondrial 1.8.1.7 0.720
3cgb FADCoenzyme A disulfide reductase / 0.720
3vqr FADPutative oxidoreductase / 0.720
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.719
1nhp FADNADH peroxidase 1.11.1.1 0.719
3bi5 FADPolyamine oxidase FMS1 / 0.719
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.719
4h4w FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.719
3nt6 FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.718
4bur FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.718
2uxx FAJLysine-specific histone demethylase 1A 1 0.717
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.717
3fg2 FADPutative rubredoxin reductase / 0.715
4opt FDAConserved Archaeal protein / 0.715
1f8r FADL-amino-acid oxidase 1.4.3.2 0.714
1f8s FADL-amino-acid oxidase 1.4.3.2 0.714
1gre FADGlutathione reductase, mitochondrial 1.8.1.7 0.714
3cgc FADCoenzyme A disulfide reductase / 0.714
1tde FADThioredoxin reductase 1.8.1.9 0.713
2x8h FADThioredoxin glutathione reductase / 0.713
4bk3 FADProbable salicylate monooxygenase / 0.713
1geu FADGlutathione reductase 1.8.1.7 0.711
5g3t FDAFlavin-dependent L-tryptophan oxidase VioA / 0.711
4yjd FADD-amino-acid oxidase 1.4.3.3 0.710
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.708
1k0j FADp-hydroxybenzoate hydroxylase / 0.708
2tpr FADTrypanothione reductase 1.8.1.12 0.708
1fec FADTrypanothione reductase 1.8.1.12 0.706
1gra FADGlutathione reductase, mitochondrial 1.8.1.7 0.706
3grs FADGlutathione reductase, mitochondrial 1.8.1.7 0.706
1c0l FADD-amino-acid oxidase 1.4.3.3 0.705
3fbs FADOxidoreductase / 0.705
3qfa FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.705
2c3d FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.704
3we0 FADLysine 2-monooxygenase / 0.703
3klj FADNADH-rubredoxin oxidoreductase 1.18.1.1 0.702
3uoy FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.702
4nte FADDepH / 0.702
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.701
3ad9 FADSubunit beta of sarcosine oxidase / 0.701
3f8r NAPNADH oxidase/thioredoxin reductase / 0.701
2apg FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.700
3r9u FADThioredoxin reductase / 0.700
2r9z FADGlutathione amide reductase / 0.699
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.699
1ger FADGlutathione reductase 1.8.1.7 0.698
3gsi FADDimethylglycine oxidase 1.5.3.10 0.698
2jk6 FADTrypanothione reductase / 0.697
3dme FADPutative conserved exported protein / 0.697
3ka7 FADPutative oxidoreductase / 0.697
3znp FADD-amino-acid oxidase 1.4.3.3 0.696
4x4j FADPutative oxygenase / 0.696
5fs7 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.696
3ics FADCoenzyme A disulfide reductase / 0.695
4opl FDAConserved Archaeal protein / 0.695
2fjb SFDAdenylylsulfate reductase, subunit A (AprA) / 0.694
2fjd SFDAdenylylsulfate reductase, subunit A (AprA) / 0.694
2tmd ADPTrimethylamine dehydrogenase 1.5.8.2 0.694
2b9x FADPutative aminooxidase / 0.693
2q7v FADThioredoxin reductase / 0.693
4j33 FADKynurenine 3-monooxygenase / 0.693
4wct FADFructosyl amine:oxygen oxidoreductase / 0.693
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.692
1qo8 FADFumarate reductase flavoprotein subunit / 0.692
1y56 ATPUncharacterized protein / 0.692
3kve FADL-amino-acid oxidase / 0.692
1djn ADPTrimethylamine dehydrogenase 1.5.8.2 0.691
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.691
1ng3 FADGlycine oxidase 1.4.3.19 0.691
1typ FADTrypanothione reductase 1.8.1.12 0.691
2yqu FADDihydrolipoyl dehydrogenase / 0.691
3lov FADProtoporphyrinogen oxidase / 0.691
1bzl FADTrypanothione reductase 1.8.1.12 0.690
2yr5 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.690
3ish FADThioredoxin reductase 1.8.1.9 0.690
4x9m FADUncharacterized protein MG039 homolog / 0.690
1npx FADNADH peroxidase 1.11.1.1 0.688
2bac FADPutative aminooxidase / 0.688
1feb FADTrypanothione reductase 1.8.1.12 0.686
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.686
1knr FADL-aspartate oxidase 1.4.3.16 0.686
2eq7 FADDihydrolipoyl dehydrogenase / 0.686
3sqp FADGlutathione reductase, mitochondrial 1.8.1.7 0.686
2x8g FADThioredoxin glutathione reductase / 0.685
4ntd FADThioredoxin reductase / 0.685
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.684
2b9w FADPutative aminooxidase / 0.684
2wow FADTrypanothione reductase / 0.684
4ynt FDAGlucose oxidase, putative / 0.684
2cfy FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.683
3gmb FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.682
3sgl FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.682
4opc FDAConserved Archaeal protein / 0.682
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.681
4fx9 FADCoenzyme A disulfide reductase 1.8.1.14 0.681
2b9y FADPutative aminooxidase / 0.680
4nev FADTrypanothione reductase / 0.680
1grg FADGlutathione reductase, mitochondrial 1.8.1.7 0.679
2aqj FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.679
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.679
2iid FADL-amino-acid oxidase 1.4.3.2 0.679
4gr1 FADGlutathione reductase, mitochondrial 1.8.1.7 0.679
4rsl FADFructosyl peptide oxidase / 0.679
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.679
4yry FADGlutamate synthase, beta subunit / 0.679
1djq ADPTrimethylamine dehydrogenase 1.5.8.2 0.677
4opu FDAConserved Archaeal protein / 0.677
5g3s FDAFlavin-dependent L-tryptophan oxidase VioA / 0.677
1c0k FADD-amino-acid oxidase 1.4.3.3 0.676
2eq6 FADDihydrolipoyl dehydrogenase / 0.676
2qae FADDihydrolipoyl dehydrogenase 1.8.1.4 0.676
4b1b FADThioredoxin reductase 1.8.1.9 0.676
4eqx FADCoenzyme A disulfide reductase / 0.676
4gdp FADPolyamine oxidase FMS1 / 0.676
1ve9 FADD-amino-acid oxidase 1.4.3.3 0.675
2jb2 FADL-amino acid oxidase / 0.675
3cge FADCoenzyme A disulfide reductase / 0.675
3v76 FDAUncharacterized protein / 0.675
4dna FADProbable glutathione reductase / 0.675
4ocg FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.675
1reo FADL-amino-acid oxidase 1.4.3.2 0.673
1zmd FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.673
3syi FADSulfide-quinone reductase / 0.673
3t37 FADPyridoxine 4-oxidase / 0.673
5i39 FADL-amino acid deaminase / 0.673
3q9t FAYUncharacterized protein / 0.672
2eq9 FADDihydrolipoyl dehydrogenase / 0.671
2jb1 FADL-amino acid oxidase / 0.671
2ylt FADPhenylacetone monooxygenase 1.14.13.92 0.671
3ean FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.671
3f8d FADNADH oxidase/thioredoxin reductase / 0.671
4cnj FADL-amino acid oxidase / 0.671
2yg6 FADPutrescine oxidase / 0.670
5ez7 FADProbable FAD-dependent oxidoreductase PA4991 / 0.669
2y48 FADLysine-specific histone demethylase 1A 1 0.668
3alj FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.668
3lxd FADFAD-dependent pyridine nucleotide-disulfide oxidoreductase / 0.668
4kpr FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.668
4u8o FDAUDP-galactopyranose mutase / 0.668
1ebd FADDihydrolipoyl dehydrogenase 1.8.1.4 0.667
1tdk FADL-amino-acid oxidase 1.4.3.2 0.667
3qfb FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.667
3uov FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.667
2v6o FADThioredoxin glutathione reductase / 0.666
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.666
3fmw FADOxygenase / 0.666
3ict FADCoenzyme A disulfide reductase / 0.666
3uth FDAUDP-galactopyranose mutase / 0.666
2zbw FADFerredoxin--NADP reductase / 0.665
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.664
4gcm FADThioredoxin reductase 1.8.1.9 0.664
4u8k FDAUDP-galactopyranose mutase / 0.664
1ng4 FADGlycine oxidase 1.4.3.19 0.663
3t14 FADSulfide-quinone reductase / 0.663
4jn9 FADDepH / 0.663
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.662
1zmc FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.662
3cgd FADCoenzyme A disulfide reductase / 0.662
3sz0 FADSulfide-quinone reductase / 0.662
4u8n FDAUDP-galactopyranose mutase / 0.662
1jeh FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.661
2f5z FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.661
2igo FADPyranose 2-oxidase / 0.661
2q0l FADThioredoxin reductase 1.8.1.9 0.661
3m0o FADMonomeric sarcosine oxidase 1.5.3.1 0.661
1rz1 FADPhenol 2-hydroxylase component B / 0.660
3lad FADDihydrolipoyl dehydrogenase / 0.660
4h50 FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.660
4m52 FADDihydrolipoyl dehydrogenase 1.8.1.4 0.660
4u8m FDAUDP-galactopyranose mutase / 0.660
2ign FADPyranose 2-oxidase / 0.659
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.658
2rgj FADFlavin-containing monooxygenase / 0.658
3bi2 FADPolyamine oxidase FMS1 / 0.658
3pl8 FADPyranose 2-oxidase / 0.658
1fea FADTrypanothione reductase 1.8.1.12 0.657
1onf FADGlutathione reductase 1.8.1.7 0.657
1ryi FADGlycine oxidase 1.4.3.19 0.657
3uox FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.657
1v59 FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.656
2e48 FADD-amino-acid oxidase 1.4.3.3 0.656
3ukf FDAUDP-galactopyranose mutase / 0.656
4i58 FADCyclohexylamine Oxidase / 0.656
4la1 FADThioredoxin glutathione reductase / 0.656
2jae FADL-amino acid oxidase / 0.655
3all FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase / 0.655
3urh FADDihydrolipoyl dehydrogenase / 0.655
4c5o FADPutative monooxygenase / 0.655
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.654
3oz2 FADDigeranylgeranylglycerophospholipid reductase / 0.654
3qj4 FADRenalase / 0.654
3ukl FADUDP-galactopyranose mutase / 0.654
1tdn FADL-amino-acid oxidase 1.4.3.2 0.653
3zdn FADMonoamine oxidase N 1.4.3.4 0.653
1x0p FADTll0078 protein / 0.652
2a8x FADDihydrolipoyl dehydrogenase 1.8.1.4 0.652
2yg7 FADPutrescine oxidase / 0.652
3t2y FADSulfide-quinone reductase / 0.652
1mok FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.651
1tdo FADL-amino-acid oxidase 1.4.3.2 0.651
2bi7 FADUDP-galactopyranose mutase 5.4.99.9 0.651
2x3n FADProbable FAD-dependent monooxygenase / 0.651
1gpe FADGlucose oxidase 1.1.3.4 0.650
1nhq FADNADH peroxidase 1.11.1.1 0.650
4dsg FADUncharacterized protein / 0.650