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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jq7KJQEpidermal growth factor receptor2.7.10.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4jq7KJQEpidermal growth factor receptor2.7.10.11.000
4jr3KJREpidermal growth factor receptor2.7.10.10.665
4jrvKJVEpidermal growth factor receptor2.7.10.10.645
4jq8KJ8Epidermal growth factor receptor2.7.10.10.639
1m17AQ4Epidermal growth factor receptor2.7.10.10.631
2itpAEEEpidermal growth factor receptor2.7.10.10.623
2itnANPEpidermal growth factor receptor2.7.10.10.618
2itvANPEpidermal growth factor receptor2.7.10.10.588
2eb3ANPEpidermal growth factor receptor2.7.10.10.583
2ittAEEEpidermal growth factor receptor2.7.10.10.580
4i231C9Epidermal growth factor receptor2.7.10.10.578
2itwITQEpidermal growth factor receptor2.7.10.10.575
4riyADPEpidermal growth factor receptor2.7.10.10.573
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.569
2itxANPEpidermal growth factor receptor2.7.10.10.567
4wkqIREEpidermal growth factor receptor2.7.10.10.564
3vjoANPEpidermal growth factor receptor2.7.10.10.563
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.555
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.554
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.550
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.547
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.545
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.537
2y6o1N1Ephrin type-A receptor 42.7.10.10.537
4gk3L87Ephrin type-A receptor 32.7.10.10.537
2hk51BMTyrosine-protein kinase HCK2.7.10.20.535
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.530
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.528
4hjoAQ4Epidermal growth factor receptor2.7.10.10.527
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.526
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.525
3ac2KSETyrosine-protein kinase Lck2.7.10.20.525
2of4979Tyrosine-protein kinase Lck2.7.10.20.523
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.523
4c02TAKActivin receptor type-12.7.11.300.523
1vjy460TGF-beta receptor type-12.7.11.300.522
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.520
1py5PY1TGF-beta receptor type-12.7.11.300.519
2of2547Tyrosine-protein kinase Lck2.7.10.20.519
3w33W19Epidermal growth factor receptor2.7.10.10.518
3acjKSSTyrosine-protein kinase Lck2.7.10.20.517
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.516
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.515
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.515
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.513
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.513
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.512
2xyuQ9GEphrin type-A receptor 42.7.10.10.511
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.509
1xkkFMMEpidermal growth factor receptor2.7.10.10.508
2gs7ANPEpidermal growth factor receptor2.7.10.10.508
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.507
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
2vwu7X1Ephrin type-B receptor 42.7.10.10.507
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.506
2vwx7X4Ephrin type-B receptor 42.7.10.10.506
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.506
3zewSTUEphrin type-B receptor 42.7.10.10.506
4i22IREEpidermal growth factor receptor2.7.10.10.506
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.505
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.505
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.504
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.503
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.503
3uvp048Mitogen-activated protein kinase 14/0.502
2ituITQEpidermal growth factor receptor2.7.10.10.501
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.501
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.499
2itqITQEpidermal growth factor receptor2.7.10.10.499
4g2fC07Ephrin type-A receptor 32.7.10.10.498
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.498
4bb432WEphrin type-B receptor 42.7.10.10.497
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.496
2qo9ANPEphrin type-A receptor 32.7.10.10.492
3dt1P40Mitogen-activated protein kinase 14/0.492
3poz03PEpidermal growth factor receptor2.7.10.10.492
3w2sW2REpidermal growth factor receptor2.7.10.10.491
4y95746Tyrosine-protein kinase/0.491
4j97ACPFibroblast growth factor receptor 2/0.490
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.488
4gk4L90Ephrin type-A receptor 32.7.10.10.487
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.487
2io6330Wee1-like protein kinase2.7.10.20.486
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.486
1u54ACPActivated CDC42 kinase 1/0.485
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.485
2vx07X7Ephrin type-B receptor 42.7.10.10.485
4fyn0VETyrosine-protein kinase SYK2.7.10.20.485
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.484
2c475IDCasein kinase I isoform gamma-2/0.483
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.483
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.483
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.482
2itzIREEpidermal growth factor receptor2.7.10.10.481
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.481
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.481
4gk2L66Ephrin type-A receptor 32.7.10.10.481
5e8wSTUTGF-beta receptor type-12.7.11.300.481
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.480
3uvqFS8Mitogen-activated protein kinase 14/0.480
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.480
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.480
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.480
2xvdAS6Ephrin type-B receptor 42.7.10.10.479
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.478
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.478
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.478
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.477
2qoqANPEphrin type-A receptor 32.7.10.10.477
2vwz7X6Ephrin type-B receptor 42.7.10.10.477
4kb81QOCasein kinase I isoform delta2.7.11.10.477
2i0ePDSProtein kinase C beta type2.7.11.130.476
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.476
3vryB43Tyrosine-protein kinase HCK2.7.10.20.476
3w32W32Epidermal growth factor receptor2.7.10.10.476
4fob0USALK tyrosine kinase receptor2.7.10.10.476
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.476
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.475
2balPQAMitogen-activated protein kinase 14/0.474
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.473
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.473
3w2rW2REpidermal growth factor receptor2.7.10.10.473
4aa5NQBMitogen-activated protein kinase 14/0.473
4kba1QMCasein kinase I isoform delta2.7.11.10.473
5e8xSTUTGF-beta receptor type-12.7.11.300.473
1agwSU2Fibroblast growth factor receptor 1/0.472
3u9eCOALmo1369 protein/0.472
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.472
1bygSTUTyrosine-protein kinase CSK/0.471
1jpaANPEphrin type-B receptor 22.7.10.10.471
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.471
2vwy7X5Ephrin type-B receptor 42.7.10.10.470
3ac1KZITyrosine-protein kinase Lck2.7.10.20.470
3och2MXDihydrofolate reductase1.5.1.30.470
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.470
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.470
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.468
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.468
3imgBZ3Pantothenate synthetase6.3.2.10.468
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.468
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.468
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.467
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.467
2j7t274Serine/threonine-protein kinase 102.7.11.10.467
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.467
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.467
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.467
4c62XWWTyrosine-protein kinase JAK2/0.467
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.467
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.467
4u7wNDPMxaA/0.467
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1rw8580TGF-beta receptor type-12.7.11.300.466
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.466
2p5uNADUDP-glucose 4-epimerase/0.466
2rg5279Mitogen-activated protein kinase 14/0.466
2zybKSLTyrosine-protein kinase Lck2.7.10.20.466
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.466
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.466
4nks2M2Fibroblast growth factor receptor 1/0.466
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.466
2wotZZGTGF-beta receptor type-12.7.11.300.465
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.465
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.465
4kbc1QJCasein kinase I isoform delta2.7.11.10.465
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
3fklFKLMitogen-activated protein kinase 14/0.464
3sp9IL2Peroxisome proliferator-activated receptor delta/0.464
5a3bAPRSIR2 family protein/0.464
2wouZZFTGF-beta receptor type-12.7.11.300.463
3gc9B45Mitogen-activated protein kinase 112.7.11.240.463
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
3mpt1GKMitogen-activated protein kinase 14/0.463
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.463
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.463
3s4qNK0Mitogen-activated protein kinase 14/0.462
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.462
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.462
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2henADPEphrin type-B receptor 22.7.10.10.461
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.461
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.461
4id71G0Activated CDC42 kinase 1/0.461
4kb81QNCasein kinase I isoform delta2.7.11.10.461
4kiq1RAMitogen-activated protein kinase 14/0.461
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.461
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.460
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.460
1di9MSQMitogen-activated protein kinase 14/0.459
1klkPMDDihydrofolate reductase1.5.1.30.459
1psa0ZLPepsin A3.4.23.10.459
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.459
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
1k6pXN3Gag-Pol polyprotein3.4.23.160.458
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.458
2vww7X2Ephrin type-B receptor 42.7.10.10.458
3gxlQIGTGF-beta receptor type-12.7.11.300.458
4j6cSTRCytochrome P450 monooxygenase/0.458
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.458
4nka2K7Fibroblast growth factor receptor 1/0.458
1di8DTQCyclin-dependent kinase 22.7.11.220.457
2izrBRKCasein kinase I isoform gamma-32.7.11.10.457
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3biz61EWee1-like protein kinase2.7.10.20.457
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.457
3tucFPWTyrosine-protein kinase SYK2.7.10.20.457
4fz60VGTyrosine-protein kinase SYK2.7.10.20.457
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.457
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.456
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.456
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.456
3gbuATPUncharacterized sugar kinase PH14592.7.10.456
3nr4PYVAbscisic acid receptor PYL2/0.456
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.456
5aacVGHALK tyrosine kinase receptor2.7.10.10.456
1f28UMPThymidylate synthase2.1.1.450.455
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.455
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.455
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.455
3iw4LW4Protein kinase C alpha type2.7.11.130.455
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.455
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.455
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2jedLG8Protein kinase C theta type2.7.11.130.454
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.454
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.454
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4hgt15GCasein kinase I isoform delta2.7.11.10.454
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.454
5eccNAPDehydrofolate reductase type I/0.454
2vttLZDCyclin-dependent kinase 22.7.11.220.453
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.453
3imgBZ2Pantothenate synthetase6.3.2.10.453
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.453
4erkOLOMitogen-activated protein kinase 12.7.11.240.453
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fnzNZFALK tyrosine kinase receptor2.7.10.10.453
4j6dTESCytochrome P450 monooxygenase/0.453
5aaaVGHALK tyrosine kinase receptor2.7.10.10.453
5iubCLRAdenosine receptor A2a/0.453
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1ouk084Mitogen-activated protein kinase 14/0.452
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.452
2hasC3OVitamin D3 receptor/0.452
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.452
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.452
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.452
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.452
3cr0809Wee1-like protein kinase2.7.10.20.451
3el4ROCGag-Pol polyprotein3.4.23.160.451
3fln3FNMitogen-activated protein kinase 14/0.451
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.451
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.451
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.451
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.451
4jia1K3Tyrosine-protein kinase JAK2/0.451
4y93746Tyrosine-protein kinase/0.451
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.450
2pwlACPFibroblast growth factor receptor 2/0.450
2znnS44Peroxisome proliferator-activated receptor alpha/0.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3s2pPMUCyclin-dependent kinase 22.7.11.220.450
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.450
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.450
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.450
4h9506UDihydrofolate reductase1.5.1.30.450
4kin1M8Mitogen-activated protein kinase 14/0.450
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.449
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.449
2bxmIMNSerum albumin/0.449
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2izt23DCasein kinase I isoform gamma-32.7.11.10.449
2py3ACPFibroblast growth factor receptor 2/0.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.449
3dds26BGlycogen phosphorylase, liver form2.4.1.10.449
3hz5Z64Heat shock protein HSP 90-alpha/0.449
3iodA6DPantothenate synthetase6.3.2.10.449
3iphG11Mitogen-activated protein kinase 14/0.449
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.449
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.449
4nbwNADShort-chain dehydrogenase/reductase SDR/0.449
1p0hACOMycothiol acetyltransferase2.3.1.1890.448
2r43G3GGag-Pol polyprotein3.4.23.160.448
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.448
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.448
3a62STURibosomal protein S6 kinase beta-12.7.11.10.448
3gfeP37Mitogen-activated protein kinase 14/0.448
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.448
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.448
4hvh19RTyrosine-protein kinase JAK32.7.10.20.448
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.448
1ay0TPPTransketolase 12.2.1.10.447
1ywrLI9Mitogen-activated protein kinase 14/0.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.447
3a783EVVitamin D3 receptor/0.447
3gggNADPrephenate dehydrogenase/0.447
3gobHXXDdmC/0.447
3iaeD7KBenzaldehyde lyase/0.447
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.447
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.447
4xwtU5PRibonuclease J/0.447
1nzdUPGDNA beta-glucosyltransferase/0.446
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
1zz2B11Mitogen-activated protein kinase 14/0.446
2qocANPEphrin type-A receptor 32.7.10.10.446
3aidARQGag-Pol polyprotein3.4.23.160.446
3btjDEQHTH-type transcriptional regulator QacR/0.446
3flwFLWMitogen-activated protein kinase 14/0.446
3lqfNADGalactitol dehydrogenase/0.446
3vt7VDXVitamin D3 receptor/0.446
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.446
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.446
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.445
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.445
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.445
2d4h5GPGuanylate-binding protein 1/0.445
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
3bgxTMPThymidylate synthase/0.445
3kf7L9GMitogen-activated protein kinase 14/0.445
3l8xN4DMitogen-activated protein kinase 14/0.445
4cdmFO1Deoxyribodipyrimidine photolyase/0.445
4jk4DIUSerum albumin/0.445
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1me8RVPInosine-5'-monophosphate dehydrogenase/0.444
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.444
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.444
3imeBZ2Pantothenate synthetase6.3.2.10.444
3l9hEMQKinesin-like protein KIF11/0.444
3vf9477Tyrosine-protein kinase SYK2.7.10.20.444
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.444
4fgg0U5Dihydrofolate reductase1.5.1.30.444
4gt3ATPMitogen-activated protein kinase 12.7.11.240.444
4xhgADPUncharacterized protein/0.444
1ir3ANPInsulin receptor2.7.10.10.443
1ppjANYCytochrome b/0.443
1rj6AZMCarbonic anhydrase 144.2.1.10.443
1t7j478Gag-Pol polyprotein3.4.23.160.443
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.443
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
2ghlLIBMitogen-activated protein kinase 14/0.443
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.443
3a1nNADNDP-sugar epimerase/0.443
3r7eX88Cyclin-dependent kinase 22.7.11.220.443
4aw530KEphrin type-B receptor 42.7.10.10.443
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.443
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.443
5jtbZMAAdenosine receptor A2a/0.443
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.442
2a1nCAMCamphor 5-monooxygenase1.14.15.10.442
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.442
2qo7ANPEphrin type-A receptor 32.7.10.10.442
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.442
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.442
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.442
3dmgSAHProbable ribosomal RNA small subunit methyltransferase/0.442
3ez2ADPPlasmid partition protein A/0.442
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.442
4btkDTQTau-tubulin kinase 12.7.11.10.442
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.442
4fz70VHTyrosine-protein kinase SYK2.7.10.20.442
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.442
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
4qms1N1Serine/threonine-protein kinase 242.7.11.10.442
5aabVGHALK tyrosine kinase receptor2.7.10.10.442
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1bwsNDPGDP-L-fucose synthase/0.441
2cig1DGDihydrofolate reductase1.5.1.30.441
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.441
3i8aN22Dihydrofolate reductase1.5.1.30.441
3mvm39PMitogen-activated protein kinase 14/0.441
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fki09KCyclin-dependent kinase 22.7.11.220.441
4iarERM5-hydroxytryptamine receptor 1B/0.441
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1u3dFADCryptochrome-1/0.440
2b7zMK1Gag-Pol polyprotein/0.440
2gr1FADFerredoxin reductase/0.440
2hamC33Vitamin D3 receptor/0.440
2q9fC3SCholesterol 24-hydroxylase/0.440
2wipP49Cyclin-dependent kinase 22.7.11.220.440
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.440
2znq401Peroxisome proliferator-activated receptor delta/0.440
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.440
3n0tOPYDipeptidyl peptidase 23.4.14.20.440
3ocgOCGMitogen-activated protein kinase 14/0.440
3qpjN4IGag-Pol polyprotein3.4.23.160.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.440
3udq09EBeta-secretase 13.4.23.460.440
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.440
4f650S9Fibroblast growth factor receptor 1/0.440
4othDRNSerine/threonine-protein kinase N1/0.440