sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.884 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.884 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.865 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.839 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.838 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.830 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.819 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.816 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.799 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.795 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.793 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.784 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.769 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.741 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.601 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.580 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.573 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.564 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.558 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.557 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.546 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.529 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.525 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.524 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.524 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.522 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.515 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.513 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.508 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.501 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.496 | |
| 4iah | 1DX | Alr2278 protein | / | 0.493 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.492 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.488 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.488 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.487 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.487 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.486 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.486 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.486 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.485 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.484 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 4iae | 1DX | Alr2278 protein | / | 0.477 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.476 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.473 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.472 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.472 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.470 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.470 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.469 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.468 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.467 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.466 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.466 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.464 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.464 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.463 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.463 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.463 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.461 | |
| 4rel | KMP | Glycosyltransferase | / | 0.461 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.460 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.459 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.459 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.458 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.458 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.456 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.456 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.455 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.455 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.455 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.454 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.454 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.453 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.453 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4jic | FMN | GTN Reductase | / | 0.453 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.452 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.452 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.451 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.451 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.450 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.449 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.449 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.449 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.449 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.448 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.448 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.448 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.447 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.447 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.447 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.447 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.447 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.446 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.446 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.446 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.446 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.446 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.446 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.445 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.445 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3eku | CY9 | Actin-5C | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.445 | |
| 4e2d | FMN | Dehydrogenase | / | 0.445 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.445 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.445 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.444 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.443 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.443 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.443 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.443 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.443 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.443 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.443 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4e2y | JHZ | Methyltransferase | / | 0.443 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.442 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.442 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.442 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.442 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.442 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.442 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.441 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.441 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.441 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.441 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.440 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
| 4n1g | CEI | Obelin | / | 0.440 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.440 |