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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fnd3H9Enoyl-CoA hydratase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fnd3H9Enoyl-CoA hydratase/1.000
5eccNAPDehydrofolate reductase type I/0.511
3w5rLOAVitamin D3 receptor/0.509
1upw444Oxysterols receptor LXR-beta/0.503
4j6dTESCytochrome P450 monooxygenase/0.501
4iteTEYVitamin D3 receptor/0.500
3vrwYS5Vitamin D3 receptor/0.498
1ai9NDPDihydrofolate reductase1.5.1.30.497
3vt5YI2Vitamin D3 receptor/0.497
1l2jETCEstrogen receptor beta/0.496
1rx8FOLDihydrofolate reductase1.5.1.30.496
3nj0PYVAbscisic acid receptor PYL2/0.494
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.494
3w0aDS5Vitamin D3 receptor/0.493
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.492
1rkgVD1Vitamin D3 receptor/0.488
2acwUPGGlycosyltransferase/0.488
5k2cZMAAdenosine receptor A2a/0.488
2zlcVDXVitamin D3 receptor/0.486
4g20484Vitamin D3 receptor A/0.486
3w0gW07Vitamin D3 receptor/0.485
5iua6DXAdenosine receptor A2a/0.485
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.484
3kpzZNEVitamin D3 receptor/0.484
3vt65YIVitamin D3 receptor/0.484
4g1z0VPVitamin D3 receptor A/0.482
3icsADPCoenzyme A disulfide reductase/0.481
5iu86DZAdenosine receptor A2a/0.481
3vrvYSDVitamin D3 receptor/0.480
3w5tLHPVitamin D3 receptor/0.480
3d84NDPDihydrofolate reductase1.5.1.30.479
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.479
1rk3VDXVitamin D3 receptor/0.478
2hc4VDXVitamin D3 receptor A/0.478
3w0iO11Vitamin D3 receptor/0.478
4c02TAKActivin receptor type-12.7.11.300.478
2zl9VDAVitamin D3 receptor/0.477
2o4rVD5Vitamin D3 receptor/0.476
1ndeMONEstrogen receptor beta/0.475
1m78NDPDihydrofolate reductase1.5.1.30.474
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.474
2harOCCVitamin D3 receptor/0.474
3vt7VDXVitamin D3 receptor/0.474
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.473
3vtbTKAVitamin D3 receptor/0.473
3w0hW12Vitamin D3 receptor/0.473
5bukFADFADH2-dependent halogenase/0.473
1db1VDXVitamin D3 receptor/0.472
2yee2ECHeat shock protein HSP 90-alpha/0.472
3a783EVVitamin D3 receptor/0.472
3w32W32Epidermal growth factor receptor2.7.10.10.472
4g2h0VQVitamin D3 receptor A/0.472
5iubCLRAdenosine receptor A2a/0.472
1phePIYCamphor 5-monooxygenase1.14.15.10.471
3vt45YIVitamin D3 receptor/0.471
4xz3COAAcyl-CoA synthetase (NDP forming)/0.471
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.470
1f5fDHTSex hormone-binding globulin/0.470
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
5iu4ZMAAdenosine receptor A2a/0.470
6cp4CAMCamphor 5-monooxygenase1.14.15.10.470
2fszOHTEstrogen receptor beta/0.469
4d9fDCSD-cysteine desulfhydrase/0.469
4fhh0U3Vitamin D3 receptor A/0.469
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
5cccDDFDihydrofolate reductase1.5.1.30.469
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
3nr4PYVAbscisic acid receptor PYL2/0.468
3qlrNDPDihydrofolate reductase1.5.1.30.468
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4fki09KCyclin-dependent kinase 22.7.11.220.468
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.468
1cqp803Integrin alpha-L/0.467
1drhNAPDihydrofolate reductase1.5.1.30.467
1ie9VDXVitamin D3 receptor/0.467
1mp0NADAlcohol dehydrogenase class-31.1.1.10.467
1rjkVDZVitamin D3 receptor/0.467
1rkhVD2Vitamin D3 receptor/0.467
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.467
2gr1FADFerredoxin reductase/0.467
2hamC33Vitamin D3 receptor/0.467
2hasC3OVitamin D3 receptor/0.467
2hcdBIVVitamin D3 receptor A/0.467
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.467
3uzcT4EAdenosine receptor A2a/0.467
3emlZMAAdenosine receptor A2a/0.467
3dmgSAHProbable ribosomal RNA small subunit methyltransferase/0.466
4eiyZMAAdenosine receptor A2a/0.466
1s0zEB1Vitamin D3 receptor/0.465
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.465
3gc9B45Mitogen-activated protein kinase 112.7.11.240.465
5k2aZMAAdenosine receptor A2a/0.465
1e1kFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.464
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.464
2hb7O1CVitamin D3 receptor/0.464
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.464
2wotZZGTGF-beta receptor type-12.7.11.300.464
3lxiCAMCytochrome P450/0.464
3qlsNDPDihydrofolate reductase1.5.1.30.464
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.464
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.464
1rx1NAPDihydrofolate reductase1.5.1.30.463
2cjpVPREpoxide hydrolase/0.463
4a2aATPCell division protein FtsA/0.463
4o71CPBBromodomain-containing protein 4/0.463
5k2bZMAAdenosine receptor A2a/0.463
1t87CAMCamphor 5-monooxygenase1.14.15.10.462
1umlFR4Adenosine deaminase3.5.4.40.462
3b6zCO7Enoyl reductase LovC10.462
4q0a4OAVitamin D3 receptor A/0.462
5cc9DDFDihydrofolate reductase1.5.1.30.462
5jtbZMAAdenosine receptor A2a/0.462
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1rx8NAPDihydrofolate reductase1.5.1.30.461
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4gl4NAIAlcohol dehydrogenase class-3/0.461
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.461
4l0qNADAlcohol dehydrogenase class-3/0.461
4qzuRTLRetinol-binding protein 2/0.461
2qblCAMCamphor 5-monooxygenase1.14.15.10.460
3koo24DBifunctional epoxide hydrolase 23.3.2.100.460
3ns2PYVAbscisic acid receptor PYL2/0.460
3oafOAGDihydrofolate reductase1.5.1.30.460
3s7a684Dihydrofolate reductase1.5.1.30.460
3vt3VDXVitamin D3 receptor/0.460
4fhi0S4Vitamin D3 receptor A/0.460
5cb5APRO-acetyl-ADP-ribose deacetylase/0.460
1urwI1PCyclin-dependent kinase 22.7.11.220.459
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.459
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.459
3inwJZBHeat shock protein HSP 90-alpha/0.459
4g1d0VKVitamin D3 receptor A/0.459
4jrvKJVEpidermal growth factor receptor2.7.10.10.459
4qmySTUSerine/threonine-protein kinase 242.7.11.10.459
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.458
1njaDCMThymidylate synthase/0.458
2xvv9DNSerum albumin/0.458
3d80Q22Dihydrofolate reductase1.5.1.30.458
3vruYS3Vitamin D3 receptor/0.458
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
1s19MC9Vitamin D3 receptor/0.457
2feuCAMCamphor 5-monooxygenase1.14.15.10.457
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.457
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.457
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
4rujVDXVitamin D3 receptor A/0.457
5uviZMAAdenosine receptor A2a/0.457
1ie8KH1Vitamin D3 receptor/0.456
1xqcAEJEstrogen receptor/0.456
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2zulSAMProbable ribosomal RNA small subunit methyltransferase/0.456
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.456
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
3tqaNDPDihydrofolate reductase/0.456
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1nq7ARLNuclear receptor ROR-beta/0.455
2ykbYKBHeat shock protein HSP 90-alpha/0.455
3gwfFADCyclohexanone monooxygenase/0.455
3ictADPCoenzyme A disulfide reductase/0.455
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.455
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4acm7YGCyclin-dependent kinase 22.7.11.220.455
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
1ia1NDPDihydrofolate reductase1.5.1.30.454
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.454
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.454
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.454
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.454
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.454
4fkj11KCyclin-dependent kinase 22.7.11.220.454
4g95OAGDihydrofolate reductase1.5.1.30.454
4j6bPLOCytochrome P450 monooxygenase/0.454
4okt198Androgen receptor/0.454
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2cig1DGDihydrofolate reductase1.5.1.30.453
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3abaFLICytochrome P450/0.453
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.453
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4k9yK9YFocal adhesion kinase 12.7.10.20.453
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.452
1txiTX5Vitamin D3 receptor/0.452
2w3vTOPDihydrofolate reductase/0.452
3da24MDCarbonic anhydrase 134.2.1.10.452
3u8hBHPPhospholipase A2, membrane associated/0.452
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.452
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
3csdEMOPutative ketoacyl reductase1.3.10.451
3gwfNAPCyclohexanone monooxygenase/0.451
3r336MEDihydrofolate reductase1.5.1.30.451
3ujlA8SAbscisic acid receptor PYL2/0.451
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.451
4kb81QNCasein kinase I isoform delta2.7.11.10.451
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1bxoPP7Penicillopepsin-13.4.23.200.450
1dr3TAPDihydrofolate reductase1.5.1.30.450
1fkwPURAdenosine deaminase3.5.4.40.450
1uxjNADMalate dehydrogenase/0.450
2wgjVGHHepatocyte growth factor receptor2.7.10.10.450
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.450
4aoxFADSteroid monooxygenase/0.450
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
5k2dZMAAdenosine receptor A2a/0.450
4z9g1Q5Corticotropin-releasing factor receptor 1/0.450
3pwhZMAAdenosine receptor A2a/0.450
1dajMOTDihydrofolate reductase1.5.1.30.449
1dz4CAMCamphor 5-monooxygenase1.14.15.10.449
1rx7FOLDihydrofolate reductase1.5.1.30.449
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.449
2duv371Cyclin-dependent kinase 22.7.11.220.449
2hb8MVDVitamin D3 receptor/0.449
2wqbQQ1Angiopoietin-1 receptor2.7.10.10.449
2ydoADNAdenosine receptor A2a/0.449
2yjxYJXHeat shock protein HSP 90-alpha/0.449
3d0bSNXHeat shock protein HSP 90-alpha/0.449
3dr1C5DVitamin D3 receptor A/0.449
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3qlwN22Dihydrofolate reductase1.5.1.30.449
3w0c6DSVitamin D3 receptor/0.449
3w5p4OAVitamin D3 receptor/0.449
3wmxNADNAD dependent epimerase/dehydratase/0.449
4g8bHL6Alpha/beta hydrolase fold protein/0.449
4l4fCAMCamphor 5-monooxygenase1.14.15.10.449
4okx198Androgen receptor/0.449
1pl8NADSorbitol dehydrogenase1.1.1.140.448
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.448
2aclREARetinoic acid receptor RXR-alpha/0.448
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2ci01CMLanosterol 14-alpha demethylase1.14.13.700.448
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.448
2zlaVDBVitamin D3 receptor/0.448
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.448
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4ek1CAMCamphor 5-monooxygenase1.14.15.10.448
4g3rCAMCamphor 5-monooxygenase1.14.15.10.448
4h9506UDihydrofolate reductase1.5.1.30.448
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
1kzjCB3Thymidylate synthase/0.447
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.447
2jn3JN3Fatty acid-binding protein, liver/0.447
2pmdGNPTranslation initiation factor 2 subunit gamma/0.447
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.447
3h0a9RARetinoic acid receptor RXR-alpha/0.447
4bgg844Activin receptor type-12.7.11.300.447
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.447
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.447
4ruoBIVVitamin D3 receptor A/0.447
1ikyMSDGag-Pol polyprotein2.7.7.490.446
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.446
2om9AJAPeroxisome proliferator-activated receptor gamma/0.446
2zbaZBATrichothecene 3-O-acetyltransferase/0.446
3d5fL41Peroxisome proliferator-activated receptor delta/0.446
3fwjCAMCamphor 5-monooxygenase1.14.15.10.446
3h3r14HCollagen type IV alpha-3-binding protein/0.446
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.446
3lfnA27Cyclin-dependent kinase 22.7.11.220.446
3w0rANPHygromycin-B 4-O-kinase2.7.1.1630.446
3wrhCAMCamphor 5-monooxygenase1.14.15.10.446
4iv21GREstrogen receptor/0.446
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.446
1f28F89Thymidylate synthase2.1.1.450.445
1jpaANPEphrin type-B receptor 22.7.10.10.445
1uy6PU3Heat shock protein HSP 90-alpha/0.445
2z97CAMCamphor 5-monooxygenase1.14.15.10.445
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3w0oADPHygromycin-B 4-O-kinase2.7.1.1630.445
4kwi1TJReductase homolog/0.445
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.445
4pv5CBWLactoylglutathione lyase4.4.1.50.445
5cb3APRO-acetyl-ADP-ribose deacetylase/0.445
1pxlCK4Cyclin-dependent kinase 22.7.11.220.444
1wc0APCAdenylate cyclase/0.444
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.444
2ittAEEEpidermal growth factor receptor2.7.10.10.444
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2xlsFADPutative flavin-containing monooxygenase/0.444
2zjwREFCasein kinase II subunit alpha2.7.11.10.444
3b9lAZZSerum albumin/0.444
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.444
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
4a7b3W4Collagenase 33.4.240.444
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.444
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4hnc0UTMandelate racemase/0.444
4ia2BIVVitamin D3 receptor A/0.444
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.444
4k5y1Q5Corticotropin-releasing factor receptor 1/0.444
3uzaT4GAdenosine receptor A2a/0.444
1disBDMDihydrofolate reductase1.5.1.30.443
1fmlRTLRetinol dehydratase/0.443
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.443
1qknRALEstrogen receptor beta/0.443
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
1uydPU8Heat shock protein HSP 90-alpha/0.443
2cchATPCyclin-dependent kinase 22.7.11.220.443
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.443
2itwITQEpidermal growth factor receptor2.7.10.10.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.443
2ovhAS0Progesterone receptor/0.443
2ydvNECAdenosine receptor A2a/0.443
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3cxhSMACytochrome b/0.443
3l63CAMCamphor 5-monooxygenase1.14.15.10.443
3s2pPMUCyclin-dependent kinase 22.7.11.220.443
3vrtYS2Vitamin D3 receptor/0.443
3w0jT08Vitamin D3 receptor/0.443
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.443
4d9eLCSD-cysteine desulfhydrase/0.443
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4nbb9CATerminal oxygenase component of carbazole/0.443
4uyf73BBromodomain-containing protein 2/0.443
4z34ON7Lysophosphatidic acid receptor 1/0.443
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1ke7LS3Cyclin-dependent kinase 22.7.11.220.442
1n06ADPRiboflavin kinase2.7.1.260.442
1og5SWFCytochrome P450 2C9/0.442
1qxlFR8Adenosine deaminase3.5.4.40.442
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.442
3h4vNAPPteridine reductase 11.5.1.330.442
4eon1ROCyclin-dependent kinase 22.7.11.220.442
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.442
4okb198Androgen receptor/0.442
1eioGCHGastrotropin/0.441
1errRALEstrogen receptor/0.441
1h1q2A6Cyclin-dependent kinase 22.7.11.220.441
1ia3TQ5Dihydrofolate reductase1.5.1.30.441
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1m79MQ1Dihydrofolate reductase1.5.1.30.441
1vjy460TGF-beta receptor type-12.7.11.300.441
1yrdCAMCamphor 5-monooxygenase1.14.15.10.441
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2jfaRALEstrogen receptor/0.441
2p5uNADUDP-glucose 4-epimerase/0.441
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.441
2ykcYKCHeat shock protein HSP 90-alpha/0.441
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.441
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3fwiCAMCamphor 5-monooxygenase1.14.15.10.441
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3oibFDAPutative acyl-CoA dehydrogenase/0.441
3pghFLPProstaglandin G/H synthase 21.14.99.10.441
3vtcTK3Vitamin D3 receptor/0.441
4iae1DXAlr2278 protein/0.441
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
5dq8FLFTranscriptional enhancer factor TEF-4/0.441
1agwSU2Fibroblast growth factor receptor 1/0.440
1hmp5GPHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.440
1s1vTNKGag-Pol polyprotein2.7.7.490.440
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2a0cCK9Cyclin-dependent kinase 22.7.11.220.440
2ardFDAFlavin-dependent tryptophan halogenase PrnA1.14.19.90.440
3cseN22Uncharacterized protein/0.440
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.440
3qly55VUncharacterized protein/0.440
3r1sX73Cyclin-dependent kinase 22.7.11.220.440
3w5q3KLVitamin D3 receptor/0.440
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.440
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.440
4x5iFOLDihydrofolate reductase1.5.1.30.440