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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r04UNQSerine/threonine-protein kinase pim-12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r04UNQSerine/threonine-protein kinase pim-12.7.11.11.000
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.599
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.594
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.592
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.592
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.572
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.568
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.567
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.565
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.562
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.560
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.558
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.551
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.551
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.551
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.546
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.544
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.544
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.544
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.543
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.542
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.542
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.541
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.541
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.540
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.540
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.538
3umw596Serine/threonine-protein kinase pim-12.7.11.10.538
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.537
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.534
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.534
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.533
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.533
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.530
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.528
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.526
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.523
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.521
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.519
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.518
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.514
3nga3NGCasein kinase II subunit alpha2.7.11.10.513
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.511
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.511
4bgg844Activin receptor type-12.7.11.300.510
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.503
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.501
4c02TAKActivin receptor type-12.7.11.300.495
4dgo0JWCasein kinase II subunit alpha2.7.11.10.493
3at4CCKCasein kinase II subunit alpha2.7.11.10.492
3axwTIDCasein kinase II subunit alpha2.7.11.10.491
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.491
4ux9ANPMitogen-activated protein kinase 82.7.11.240.491
2iw84SPCyclin-dependent kinase 22.7.11.220.490
3q9xEMOCasein kinase II subunit alpha2.7.11.10.490
4dgnLU2Casein kinase II subunit alpha2.7.11.10.490
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.489
3mtfA3FActivin receptor type-12.7.11.300.489
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.489
1oiyN41Cyclin-dependent kinase 22.7.11.220.488
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.487
3owj1ELCasein kinase II subunit alpha2.7.11.10.486
3r0tFU9Casein kinase II subunit alpha2.7.11.10.486
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.485
1xjdSTUProtein kinase C theta type2.7.11.130.484
1om1IQACasein kinase II subunit alpha2.7.11.10.483
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
3be9P04Casein kinase II subunit alpha2.7.11.10.483
4gmy0X5Tyrosine-protein kinase JAK2/0.483
5cu6ATPCasein kinase II subunit alpha2.7.11.10.483
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
3mdvCL6Cholesterol 24-hydroxylase/0.481
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.481
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.481
2wihP48Cyclin-dependent kinase 22.7.11.220.480
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.480
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.479
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.479
2pvnP63Casein kinase II subunit alpha2.7.11.10.479
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.479
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.478
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.478
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.478
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.478
4grb0XGCasein kinase II subunit alpha2.7.11.10.478
1m2qMNXCasein kinase II subunit alpha2.7.11.10.476
5cvhADPCasein kinase II subunit alpha2.7.11.10.476
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.475
4qmpDKISerine/threonine-protein kinase 242.7.11.10.475
3gwfFADCyclohexanone monooxygenase/0.474
3oom507Activin receptor type-12.7.11.300.474
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
2h96893Mitogen-activated protein kinase 82.7.11.240.473
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.473
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.473
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.472
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.472
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.472
3u4uLNHCasein kinase II subunit alpha2.7.11.10.472
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.472
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.471
1q1rFADPutidaredoxin reductase1.18.1.50.471
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.471
3pe2E1BCasein kinase II subunit alpha2.7.11.10.471
3vt8YI3Vitamin D3 receptor/0.471
4i22IREEpidermal growth factor receptor2.7.10.10.471
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.470
1vjy460TGF-beta receptor type-12.7.11.300.470
3mb601ICasein kinase II subunit alpha2.7.11.10.470
3h4vNAPPteridine reductase 11.5.1.330.469
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.469
4dymIYZActivin receptor type-12.7.11.300.469
4jq8KJ8Epidermal growth factor receptor2.7.10.10.469
4qmySTUSerine/threonine-protein kinase 242.7.11.10.469
1m2rMNYCasein kinase II subunit alpha2.7.11.10.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
1m2pHNACasein kinase II subunit alpha2.7.11.10.467
4enhFVXCholesterol 24-hydroxylase/0.467
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.467
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.466
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.466
4anmWULCasein kinase II subunit alpha2.7.11.10.466
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
3at3ATKCasein kinase II subunit alpha2.7.11.10.465
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.465
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.465
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.465
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.464
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.464
2zdu446Mitogen-activated protein kinase 102.7.11.240.464
3du8553Glycogen synthase kinase-3 beta2.7.11.260.464
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.464
1dawANPCasein kinase II subunit alpha2.7.11.10.463
1lp4ANPCasein kinase II subunit alpha2.7.11.10.463
2q9fC3SCholesterol 24-hydroxylase/0.463
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.463
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.463
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.463
4jqeANPCasein kinase II subunit alpha2.7.11.10.463
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.463
1bsvNDPGDP-L-fucose synthase/0.462
2iw94SPCyclin-dependent kinase 22.7.11.220.462
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.462
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.462
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4gub0Y4Casein kinase II subunit alpha2.7.11.10.462
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
5e8xSTUTGF-beta receptor type-12.7.11.300.462
1bygSTUTyrosine-protein kinase CSK/0.461
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.461
2zdt46CMitogen-activated protein kinase 102.7.11.240.461
3v3vMYUMitogen-activated protein kinase 82.7.11.240.461
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.461
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
1oi9N20Cyclin-dependent kinase 22.7.11.220.460
2wotZZGTGF-beta receptor type-12.7.11.300.460
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.460
4btjATPTau-tubulin kinase 12.7.11.10.460
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
4q73FADBifunctional protein PutA/0.460
4tuvCPZCytochrome P450 1191.140.460
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.460
1rfvADPPyridoxal kinase2.7.1.350.459
1zys199Serine/threonine-protein kinase Chk12.7.11.10.459
2qo9ANPEphrin type-A receptor 32.7.10.10.459
3vt7VDXVitamin D3 receptor/0.459
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.459
4j97ACPFibroblast growth factor receptor 2/0.459
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.459
5e8wSTUTGF-beta receptor type-12.7.11.300.459
1fmjRTLRetinol dehydratase/0.458
2zjwREFCasein kinase II subunit alpha2.7.11.10.458
3ormAGSSerine/threonine protein kinase/0.458
4q72FADBifunctional protein PutA/0.458
1vyw292Cyclin-dependent kinase 22.7.11.220.457
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.457
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.457
3gxlQIGTGF-beta receptor type-12.7.11.300.457
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.457
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.457
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.457
4riyADPEpidermal growth factor receptor2.7.10.10.457
1bxoPP7Penicillopepsin-13.4.23.200.456
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.456
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
2ociTYCValacyclovir hydrolase3.10.456
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.456
4c4jX21Dual specificity protein kinase TTK2.7.12.10.456
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4wboANWRhodopsin kinase/0.456
4yuqKS1Calmodulin-like domain protein kinase/0.456
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.456
1di8DTQCyclin-dependent kinase 22.7.11.220.455
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2hog710Serine/threonine-protein kinase Chk12.7.11.10.455
2wxvWXVCyclin-dependent kinase 22.7.11.220.455
3iw4LW4Protein kinase C alpha type2.7.11.130.455
3qu0X40Cyclin-dependent kinase 22.7.11.220.455
4hgt15GCasein kinase I isoform delta2.7.11.10.455
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.455
4yswFADXanthine dehydrogenase/oxidase/0.455
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
1jioDEB6-deoxyerythronolide B hydroxylase/0.454
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.454
1rx8NAPDihydrofolate reductase1.5.1.30.454
2excJNKMitogen-activated protein kinase 102.7.11.240.454
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.454
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.454
2xikJ60Serine/threonine-protein kinase 252.7.11.10.454
3sheI85MAP kinase-activated protein kinase 32.7.11.10.454
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.454
4jr7GNPCasein kinase II subunit alpha2.7.11.10.454
2jn3JN3Fatty acid-binding protein, liver/0.453
3a60STURibosomal protein S6 kinase beta-12.7.11.10.453
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.453
3r71X86Cyclin-dependent kinase 22.7.11.220.453
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4dgmAGICasein kinase II subunit alpha2.7.11.10.453
4gg70J8Hepatocyte growth factor receptor2.7.10.10.453
4kbk1QGCasein kinase I isoform delta2.7.11.10.453
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.452
2p33J07Mitogen-activated protein kinase 102.7.11.240.452
3ig7EFPCyclin-dependent kinase 22.7.11.220.452
3r3c4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
4l0qNADAlcohol dehydrogenase class-3/0.452
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.452
4xiwAZMCarbonic anhydrase, alpha type/0.452
1aq1STUCyclin-dependent kinase 22.7.11.220.451
1pkdUCNCyclin-dependent kinase 22.7.11.220.451
1xddAAYIntegrin alpha-L/0.451
1ywrLI9Mitogen-activated protein kinase 14/0.451
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.451
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.451
2xa4AZ5Tyrosine-protein kinase JAK2/0.451
2y3rTRKTamL/0.451
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.451
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.451
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.451
3ttjJBIMitogen-activated protein kinase 102.7.11.240.451
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.451
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4fkt48KCyclin-dependent kinase 22.7.11.220.451
4g170VNCasein kinase I isoform gamma-32.7.11.10.451
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.451
4kb81QNCasein kinase I isoform delta2.7.11.10.451
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.451
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1rfuADPPyridoxal kinase2.7.1.350.450
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2b1pAIZMitogen-activated protein kinase 102.7.11.240.450
2pvlP55Casein kinase II subunit alpha2.7.11.10.450
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3hazFADBifunctional protein PutA/0.450
3l8p0CEAngiopoietin-1 receptor2.7.10.10.450
3oroAGSSerine/threonine protein kinase/0.450
3rni21ZCyclin-dependent kinase 22.7.11.220.450
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
3vrwYS5Vitamin D3 receptor/0.450
4e730NRMitogen-activated protein kinase 82.7.11.240.450
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.450
4othDRNSerine/threonine-protein kinase N1/0.450
4rupH97Vitamin D3 receptor A/0.450
4ryvZEAProtein LlR18A/0.450
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1v35NAIEnoyl-ACP reductase/0.449
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.449
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.449
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.449
3q9zTXQCasein kinase II subunit alpha2.7.11.10.449
3rak03ZCyclin-dependent kinase 22.7.11.220.449
3unk0BYCyclin-dependent kinase 22.7.11.220.449
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.449
3zuxTCHTransporter/0.449
4bbe3O4Tyrosine-protein kinase JAK2/0.449
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.449
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.449
5cshATPCasein kinase II subunit alpha2.7.11.10.449
1gij2PUCyclin-dependent kinase 22.7.11.220.448
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.448
1ppm0P1Penicillopepsin-13.4.23.200.448
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.448
3a4vNADNDP-sugar epimerase/0.448
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.448
3gc9B45Mitogen-activated protein kinase 112.7.11.240.448
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.448
3owk18ECasein kinase II subunit alpha2.7.11.10.448
3pe13NGCasein kinase II subunit alpha2.7.11.10.448
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
3u8w09JMitogen-activated protein kinase 14/0.448
3vt9YI4Vitamin D3 receptor/0.448
4cdmFO1Deoxyribodipyrimidine photolyase/0.448
4eiyZMAAdenosine receptor A2a/0.448
4eol1ROCyclin-dependent kinase 22.7.11.220.448
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4lxhC1EAlpha/beta hydrolase fold/0.448
4wkqIREEpidermal growth factor receptor2.7.10.10.448
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.448
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1ay0TPPTransketolase 12.2.1.10.447
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.447
2pvhP19Casein kinase II subunit alpha2.7.11.10.447
2vf0F89Thymidylate synthase/0.447
3d84NDPDihydrofolate reductase1.5.1.30.447
3mdmFJZCholesterol 24-hydroxylase/0.447
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.447
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.447
4c59FEFCyclin-G-associated kinase2.7.11.10.447
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.447
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.447
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.447
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.447
1h1s4SPCyclin-dependent kinase 22.7.11.220.446
1ia3TQ5Dihydrofolate reductase1.5.1.30.446
1jpaANPEphrin type-B receptor 22.7.10.10.446
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.446
1u54ACPActivated CDC42 kinase 1/0.446
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.446
2cchATPCyclin-dependent kinase 22.7.11.220.446
2itqITQEpidermal growth factor receptor2.7.10.10.446
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.446
3b7dCNIGlutamate receptor 2/0.446
3qtzX42Cyclin-dependent kinase 22.7.11.220.446
3roy22ZCyclin-dependent kinase 22.7.11.220.446
3w5rLOAVitamin D3 receptor/0.446
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.446
4bchT7ZCyclin-dependent kinase 92.7.11.220.446
4ez50RSCyclin-dependent kinase 62.7.11.220.446
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.446
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
1eh4IC1Casein kinase I homolog 12.7.11.10.445
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2bkzSBCCyclin-dependent kinase 22.7.11.220.445
2i40BLZCyclin-dependent kinase 22.7.11.220.445
2izrBRKCasein kinase I isoform gamma-32.7.11.10.445
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3wmxNADNAD dependent epimerase/dehydratase/0.445
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.445
4gk2L66Ephrin type-A receptor 32.7.10.10.445
4hnf16WCasein kinase I isoform delta2.7.11.10.445
4hvh19RTyrosine-protein kinase JAK32.7.10.20.445
4iteTEYVitamin D3 receptor/0.445
1fvv107Cyclin-dependent kinase 22.7.11.220.444
1oiuN76Cyclin-dependent kinase 22.7.11.220.444
1ojtFADDihydrolipoyl dehydrogenase/0.444
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1zeoC01Peroxisome proliferator-activated receptor gamma/0.444
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.444
2q61SF1Peroxisome proliferator-activated receptor gamma/0.444
3cv9VDXVitamin D3 dihydroxylase/0.444
3ddpRC8Cyclin-dependent kinase 22.7.11.220.444
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.444
3nwq2NCGag-Pol polyprotein3.4.23.160.444
3pe6ZYHMonoglyceride lipase/0.444
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4c62XWWTyrosine-protein kinase JAK2/0.444
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.444
4hni16WCasein kinase I isoform epsilon2.7.11.10.444
5auuLU2Death-associated protein kinase 12.7.11.10.444
1fwkADPHomoserine kinase2.7.1.390.443
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.443
1ouk084Mitogen-activated protein kinase 14/0.443
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
1v0oINRCell division control protein 2 homolog2.7.11.220.443
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.443
1y0s331Peroxisome proliferator-activated receptor delta/0.443
1zhwHC2Oxysterol-binding protein homolog 4/0.443
1zrzBI1Protein kinase C iota type2.7.11.130.443
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.443
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.443
2in6839Wee1-like protein kinase2.7.10.20.443
2om9AJAPeroxisome proliferator-activated receptor gamma/0.443
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.443
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.443
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3eljGS7Mitogen-activated protein kinase 82.7.11.240.443
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3r7iX9ICyclin-dependent kinase 22.7.11.220.443
3r9hZ67Cyclin-dependent kinase 22.7.11.220.443
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.443
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.443
4cd2FOLDihydrofolate reductase1.5.1.30.443
4e5yNDPGDP-L-fucose synthase1.1.1.2710.443
4gk3L87Ephrin type-A receptor 32.7.10.10.443
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
5cvfATPCasein kinase II subunit alpha2.7.11.10.443
1d2sDHTSex hormone-binding globulin/0.442
1dhiMTXDihydrofolate reductase1.5.1.30.442
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.442
2b52D42Cyclin-dependent kinase 22.7.11.220.442
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.442
2j0j4STFocal adhesion kinase 12.7.10.20.442
2znpK55Peroxisome proliferator-activated receptor delta/0.442
2znq401Peroxisome proliferator-activated receptor delta/0.442
3jskAHZThiamine thiazole synthase/0.442
3lqfNADGalactitol dehydrogenase/0.442
3mvl38PMitogen-activated protein kinase 14/0.442
3nmpPYVAbscisic acid receptor PYL2/0.442
3owl19ECasein kinase II subunit alpha2.7.11.10.442
3u9eCOALmo1369 protein/0.442
3vetADPnebramycin 5' synthase6.1.2.20.442
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.442
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.442
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4fv7E94Mitogen-activated protein kinase 12.7.11.240.442
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.442
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.442
1jmhUMPThymidylate synthase/0.441
1k6tXN1Gag-Pol polyprotein3.4.23.160.441
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.441
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.441
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.441
3cgcFADCoenzyme A disulfide reductase/0.441
3gubGUBDeath-associated protein kinase 12.7.11.10.441
3nr4PYVAbscisic acid receptor PYL2/0.441
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3uli1N3Cyclin-dependent kinase 22.7.11.220.441
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.441
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4fkv61KCyclin-dependent kinase 22.7.11.220.441
4fx360KCyclin-dependent kinase 22.7.11.220.441
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.441
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.441
4jia1K3Tyrosine-protein kinase JAK2/0.441
4lfiGNPCasein kinase II subunit alpha2.7.11.10.441
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1cjkFOKAdenylate cyclase type 2/0.440
1cjkFOKAdenylate cyclase type 5/0.440
1ke6LS2Cyclin-dependent kinase 22.7.11.220.440
1ke9LS5Cyclin-dependent kinase 22.7.11.220.440
2vwx7X4Ephrin type-B receptor 42.7.10.10.440
2w17I19Cyclin-dependent kinase 22.7.11.220.440
2xnbY8LCyclin-dependent kinase 22.7.11.220.440
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.440
3csdEMOPutative ketoacyl reductase1.3.10.440
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.440
3ortAGSSerine/threonine protein kinase/0.440
3p84FMNPentaerythritol tetranitrate reductase/0.440
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.440
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.440
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.440
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.440
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.440