sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4hhd | FMN | Phototropin-1 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4hhd | FMN | Phototropin-1 | 2.7.11.1 | 1.000 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.631 | |
| 5djt | FMN | NPH1-2 | / | 0.605 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.598 | |
| 3ue6 | FMN | Aureochrome1 | / | 0.598 | |
| 5dju | FMN | NPH1-2 | / | 0.586 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.584 | |
| 2v1a | FMN | NPH1-1 | / | 0.567 | |
| 3is2 | FAD | Vivid PAS protein VVD | / | 0.567 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.566 | |
| 5dkk | FMN | Predicted protein | / | 0.564 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.563 | |
| 1n9l | FMN | Putative blue light receptor | / | 0.558 | |
| 4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.544 | |
| 4eeu | FMN | Phototropin-2 | 2.7.11.1 | 0.542 | |
| 1g28 | FMN | PHY3 | / | 0.541 | |
| 2v0u | FMN | NPH1-1 | / | 0.540 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.532 | |
| 2pd8 | FAD | Vivid PAS protein VVD | / | 0.531 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.530 | |
| 1n9n | FMN | Putative blue light receptor | / | 0.528 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.527 | |
| 4hj6 | FMN | LOV protein | / | 0.523 | |
| 5efw | FMN | NPH1-1 | / | 0.518 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.516 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.516 | |
| 2mwg | FMN | Blue-light photoreceptor | / | 0.502 | |
| 4ees | FMN | Phototropin-2 | 2.7.11.1 | 0.499 | |
| 4hia | FMN | LOV protein | / | 0.499 | |
| 5j4e | FMN | Sensory box protein | / | 0.499 | |
| 5j3w | FMN | Sensory box protein | / | 0.489 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.484 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 4hnb | FMN | LOV protein | / | 0.482 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 4hj3 | FMN | LOV protein | / | 0.481 | |
| 3sw1 | FMN | Sensory box protein | / | 0.480 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 4hj4 | FMN | LOV protein | / | 0.478 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 3t99 | ADP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.474 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.472 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.472 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3t9a | ANP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.471 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.470 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 3u9e | COA | Lmo1369 protein | / | 0.468 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.466 | |
| 2e08 | SAH | Diphthine synthase | / | 0.465 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.464 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.463 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.463 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.462 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.462 | |
| 4kuo | RBF | Putative blue-light photoreceptor | / | 0.462 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.461 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.460 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.459 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1jr8 | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.457 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2y3r | TIR | TamL | / | 0.457 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.457 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.457 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.456 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.456 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.456 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.456 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.455 | |
| 1t1s | CBQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.455 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.455 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.455 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.455 | |
| 4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 1eio | GCH | Gastrotropin | / | 0.454 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.454 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.454 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.454 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.454 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3tm0 | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4l9k | EHF | Serum albumin | / | 0.454 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.453 | |
| 2gej | GDD | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.453 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.453 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.453 | |
| 3rdq | DTB | Streptavidin | / | 0.453 | |
| 3ruq | ADP | Chaperonin | / | 0.453 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.453 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.452 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 2e4n | SAH | Diphthine synthase | / | 0.452 | |
| 2el3 | SAH | Diphthine synthase | / | 0.452 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.452 | |
| 2p6l | SAH | Diphthine synthase | / | 0.452 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 1j7u | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.451 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 2e8h | SAH | Diphthine synthase | / | 0.451 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.451 | |
| 2xzw | ATP | Nitrogen regulatory protein P-II | / | 0.451 | |
| 2y3r | TRK | TamL | / | 0.451 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.451 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.450 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 2nom | DUT | Poly(A) polymerase, putative | / | 0.450 | |
| 2owu | SAH | Diphthine synthase | / | 0.450 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.450 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.450 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.449 | |
| 4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.449 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.449 | |
| 1sez | FAD | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.448 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.448 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.448 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.448 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.448 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 2eeq | SAH | Diphthine synthase | / | 0.447 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.447 | |
| 3gob | HXX | DdmC | / | 0.447 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.446 | |
| 2pch | SAH | Diphthine synthase | / | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.446 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4ku3 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.446 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 5a3b | APR | SIR2 family protein | / | 0.446 | |
| 1qy5 | NEC | Endoplasmin | / | 0.445 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.445 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3ruv | ANP | Chaperonin | / | 0.445 | |
| 3t9f | ADP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.445 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.445 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.445 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.444 | |
| 2p2x | SAH | Diphthine synthase | / | 0.444 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.444 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.444 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 4kuk | RBF | Putative blue-light photoreceptor | / | 0.444 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4q4c | ADP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.444 | |
| 4xj3 | GTP | Cyclic GMP-AMP synthase | / | 0.444 | |
| 5fm6 | ADP | RuvB-like helicase | / | 0.444 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.443 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.443 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.443 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 4kq2 | U5P | Glycogen [starch] synthase isoform 2 | 2.4.1.11 | 0.443 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.442 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2psv | MUV | Protease | / | 0.442 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.442 | |
| 2z6r | SAH | Diphthine synthase | / | 0.442 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.442 | |
| 3t9e | ADP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.442 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4yau | 2AM | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.442 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 2huq | SAH | Diphthine synthase | / | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2xvu | 9DN | Serum albumin | / | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3okx | SAM | S-adenosyl-L-methionine-binding protein RPA0152 | / | 0.441 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4fvr | ATP | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.441 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 1jst | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.440 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4a4q | UX9 | Pol protein | / | 0.440 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.440 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.440 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.440 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.440 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.440 |