sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4c03 | SFG | Protein arginine N-methyltransferase 6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4c03 | SFG | Protein arginine N-methyltransferase 6 | / | 1.000 | |
| 5dxj | SFG | Histone-arginine methyltransferase CARM1 | / | 0.604 | |
| 5dwq | SFG | Histone-arginine methyltransferase CARM1 | / | 0.600 | |
| 5dx1 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.584 | |
| 2y1w | SFG | Histone-arginine methyltransferase CARM1 | / | 0.580 | |
| 1f3l | SAH | Protein arginine N-methyltransferase 3 | / | 0.578 | |
| 5dx8 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.575 | |
| 2y1x | SAH | Histone-arginine methyltransferase CARM1 | / | 0.574 | |
| 3b3f | SAH | Histone-arginine methyltransferase CARM1 | / | 0.561 | |
| 5dxa | SFG | Histone-arginine methyltransferase CARM1 | / | 0.559 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.546 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.538 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.520 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.519 | |
| 4hh4 | SAH | CcbJ | / | 0.510 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.508 | |
| 5icf | SAH | (S)-norcoclaurine 6-O-methyltransferase | / | 0.506 | |
| 3lcv | SAM | 16S rRNA (guanine(1405)-N(7))-methyltransferase | 2.1.1.179 | 0.497 | |
| 4qpp | SAH | Protein arginine N-methyltransferase 6 | / | 0.497 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.495 | |
| 3reo | SAH | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.492 | |
| 3dlc | SAM | SAM (And some other nucleotide) binding motif:Generic methyltransferase | / | 0.489 | |
| 1mep | BTN | Streptavidin | / | 0.488 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.488 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.487 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.483 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.481 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.481 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.481 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.481 | |
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase | / | 0.481 | |
| 2bzg | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.480 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.479 | |
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.479 | |
| 4r6x | SAH | Phosphoethanolamine N-methyltransferase | / | 0.479 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.477 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.477 | |
| 4qnu | GEK | tRNA U34 carboxymethyltransferase | / | 0.477 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.476 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.476 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.476 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.476 | |
| 4kvz | SAH | PtnL protein | / | 0.476 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.475 | |
| 4kwc | SAH | Methyltransferase domain family | / | 0.475 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.475 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.475 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.474 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.474 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.473 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.473 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.473 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4ymg | SAM | Putative SAM-dependent O-methyltranferase | / | 0.473 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.472 | |
| 5bw4 | SAM | Uncharacterized protein | / | 0.472 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.471 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.470 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.470 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.470 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.470 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.470 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.470 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.470 | |
| 1sre | HAB | Streptavidin | / | 0.469 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.469 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.469 | |
| 4e32 | DWN | Methyltransferase | / | 0.469 | |
| 4fgz | SAH | Phosphoethanolamine N-methyltransferase | / | 0.469 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.469 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.468 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.468 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.467 | |
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 0.467 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.467 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.467 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.467 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.467 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.467 | |
| 2zsc | BTN | Tamavidin2 | / | 0.467 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 3t7t | SAH | Uncharacterized protein | / | 0.466 | |
| 5epe | SAH | Uncharacterized protein | / | 0.466 | |
| 3p2k | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.465 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.464 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3grr | SAH | Probable ribosomal RNA small subunit methyltransferase A | / | 0.463 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.463 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.462 | |
| 1jr4 | CL4 | Catechol O-methyltransferase | 2.1.1.6 | 0.462 | |
| 1sri | DMB | Streptavidin | / | 0.462 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.462 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.462 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.461 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.461 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.461 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.461 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.460 | |
| 1yob | FMN | Flavodoxin 2 | / | 0.460 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.460 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.459 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.459 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.459 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.458 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.458 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.458 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.458 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.458 | |
| 4m37 | SAH | Protein arginine N-methyltransferase 7 | 2.1.1 | 0.458 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.458 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.457 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.457 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.457 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.457 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.457 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.456 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.456 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
| 3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.456 | |
| 3r96 | ACO | MccE protein | / | 0.456 | |
| 4j7h | TRH | PCZA361.3 | / | 0.456 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.456 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.455 | |
| 1g28 | FMN | PHY3 | / | 0.455 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.455 | |
| 1swn | BTN | Streptavidin | / | 0.455 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.455 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.454 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.454 | |
| 1wnb | NAI | Gamma-aminobutyraldehyde dehydrogenase | 1.2.1.19 | 0.454 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.454 | |
| 3klb | FMN | Uncharacterized protein | / | 0.454 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.454 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.453 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.453 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.453 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.453 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.453 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.453 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.453 | |
| 3kpj | SAH | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.453 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.453 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.453 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.452 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.452 | |
| 3ely | SAH | Methyltransferase | / | 0.452 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 1p1c | SAH | Guanidinoacetate N-methyltransferase | 2.1.1.2 | 0.451 | |
| 1sg9 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.451 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.451 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.451 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.451 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.451 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1r4l | XX5 | Angiotensin-converting enzyme 2 | 3.4.17.23 | 0.450 | |
| 1rjd | SAM | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.450 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.450 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2ytz | SAH | tRNA (guanine(26)-N(2))-dimethyltransferase | / | 0.450 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.450 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.450 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.450 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.450 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1nc9 | IMI | Streptavidin | / | 0.449 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.449 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.449 | |
| 2zfu | SAH | Ribosomal RNA-processing protein 8 | / | 0.449 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.449 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.449 | |
| 4qdk | SAH | Magnesium-protoporphyrin O-methyltransferase | 2.1.1.11 | 0.449 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.449 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.448 | |
| 1ngc | ADP | Heat shock cognate 71 kDa protein | / | 0.448 | |
| 1r2j | FAD | FkbI | / | 0.448 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.448 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3qbw | ADP | Anhydro-N-acetylmuramic acid kinase | / | 0.448 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.448 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.448 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.448 | |
| 4zob | LGC | Lin1840 protein | / | 0.448 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.447 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.447 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.447 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.447 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
| 2rtr | IMI | Streptavidin | / | 0.447 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.447 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.447 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 4bue | JQF | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.447 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.447 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.446 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.446 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.446 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.446 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.446 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.446 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.446 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.446 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.446 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.446 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.445 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.445 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.445 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.445 | |
| 2dph | NAD | Formaldehyde dismutase | / | 0.445 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.445 | |
| 3bwc | SAM | Spermidine synthase, putative | / | 0.445 | |
| 3oe1 | TDL | Pyruvate decarboxylase | 4.1.1.1 | 0.445 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.445 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4hdg | GTP | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4krh | SAM | Phosphoethanolamine N-methyltransferase 2 | / | 0.445 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.444 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.444 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2gr0 | ADP | Ferredoxin reductase | / | 0.444 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.444 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3krf | IPE | Geranyl diphosphate synthase large subunit | / | 0.444 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3rme | RME | Acidic mammalian chitinase | 3.2.1.14 | 0.444 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bmo | FMN | Protein NrdI | / | 0.444 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.444 | |
| 4io8 | 3FD | Heat shock 70 kDa protein 1B | / | 0.444 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.444 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.443 | |
| 1kr5 | SAH | Protein-L-isoaspartate(D-aspartate) O-methyltransferase | 2.1.1.77 | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.443 | |
| 2r8p | T6F | Transketolase 1 | / | 0.443 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2ylw | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.443 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.443 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.443 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.443 | |
| 4coj | CTP | Uncharacterized protein | / | 0.443 | |
| 4ggz | BTN | Bll1558 protein | / | 0.443 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.443 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.442 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1rje | SAH | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.442 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.442 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 0.442 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.442 | |
| 3dga | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3ea0 | ATP | ATPase, ParA family | / | 0.442 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.442 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.442 | |
| 3vc1 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.442 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.442 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4wxg | 2BO | Serine hydroxymethyltransferase | / | 0.442 | |
| 1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.441 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.441 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1khh | SAH | Guanidinoacetate N-methyltransferase | 2.1.1.2 | 0.441 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.441 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.441 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.441 | |
| 3kr8 | XAV | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.441 | |
| 3wst | SAH | Protein arginine N-methyltransferase 7 | 2.1.1 | 0.441 | |
| 4e2x | SAH | Methyltransferase | / | 0.441 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.441 | |
| 4rdi | ATP | tRNA threonylcarbamoyladenosine dehydratase | 6.1 | 0.441 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.441 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.440 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.440 | |
| 1swe | BTN | Streptavidin | / | 0.440 | |
| 1swt | BTN | Streptavidin | / | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.440 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.440 | |
| 3ogx | H1S | Peptidoglycan recognition protein 1 | / | 0.440 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4bj8 | BTN | Avidin | / | 0.440 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.440 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.440 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 4u7w | NDP | MxaA | / | 0.440 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.440 |