sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qkd | HI0 | Bcl-2-like protein 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3qkd | HI0 | Bcl-2-like protein 1 | / | 1.000 | |
| 2yxj | N3C | Bcl-2-like protein 1 | / | 0.690 | |
| 1ysi | N3B | Bcl-2-like protein 1 | / | 0.539 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.516 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.516 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.504 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.503 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.503 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.501 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.497 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.496 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.496 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.494 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.493 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.493 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.493 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.493 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.490 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.490 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.489 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.489 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.488 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.488 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.487 | |
| 2o2m | LI0 | Bcl-2-like protein 1 | / | 0.486 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.486 | |
| 3cse | N22 | Uncharacterized protein | / | 0.486 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.486 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.486 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.485 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.483 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.483 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.482 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.482 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.481 | |
| 3up0 | D7S | aceDAF-12 | / | 0.481 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.481 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.481 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.480 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.480 | |
| 4qnq | 1XJ | Bcl-2-like protein 1 | / | 0.480 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.479 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.479 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.478 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.477 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.476 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.475 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.474 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.474 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.474 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.474 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.474 | |
| 3eek | 53S | Uncharacterized protein | / | 0.474 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.474 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.474 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.473 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.473 | |
| 3a8i | C2F | Aminomethyltransferase | 2.1.2.10 | 0.472 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.472 | |
| 3eel | 53T | Uncharacterized protein | / | 0.472 | |
| 3inq | X0J | Bcl-2-like protein 1 | / | 0.472 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.472 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.471 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.471 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.471 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.471 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.471 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.471 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.471 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.470 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.470 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.470 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.470 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.470 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.469 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.469 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.469 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.469 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.469 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.469 | |
| 2yiu | SMA | Cytochrome b | / | 0.469 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.469 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.469 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.468 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.468 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.468 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.468 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.468 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.467 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.467 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.467 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.467 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.467 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.467 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 5doz | NDP | JamJ | / | 0.467 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.466 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.466 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.466 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.465 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.465 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.465 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.465 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.465 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3ghh | 2NF | CD38 molecule | / | 0.464 | |
| 3qly | 55V | Uncharacterized protein | / | 0.464 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.464 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.464 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.464 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.463 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.463 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.463 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.462 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.462 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.462 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.462 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.462 | |
| 4iae | 1DX | Alr2278 protein | / | 0.462 | |
| 4l8u | 9AZ | Serum albumin | / | 0.462 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.462 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.462 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.461 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.461 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.461 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.461 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.461 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.461 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.460 | |
| 2bxo | OPB | Serum albumin | / | 0.460 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.460 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.460 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.460 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 1ppj | ANY | Cytochrome b | / | 0.459 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2cul | FAD | GidA-related protein | / | 0.459 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.459 | |
| 3gn2 | AX8 | Pteridine reductase | / | 0.459 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.459 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.459 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.459 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.459 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.459 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.458 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.458 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.458 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.458 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.458 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.458 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.457 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.457 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.457 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.457 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.456 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.456 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.456 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.456 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.456 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.456 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.456 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.456 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.456 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.456 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.456 | |
| 4c3s | NAD | Aldehyde Dehydrogenase | / | 0.456 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.456 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.456 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.455 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.455 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.455 | |
| 3wzn | BTN | Streptavidin | / | 0.455 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.455 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.455 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.455 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.455 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.454 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.454 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.454 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.454 | |
| 3zra | ORB | Progesterone receptor | / | 0.454 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.454 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.454 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1fml | RTL | Retinol dehydratase | / | 0.453 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.453 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.453 | |
| 2qjy | SMA | Cytochrome b | / | 0.453 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.453 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.453 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.453 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4iqq | D16 | Thymidylate synthase | / | 0.453 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.453 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.453 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.452 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.452 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.452 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.452 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.452 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.451 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.451 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.451 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.451 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.451 | |
| 4ea0 | 651 | Dehydrosqualene synthase | / | 0.451 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.451 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.451 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.450 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.450 | |
| 1syn | F89 | Thymidylate synthase | / | 0.450 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.450 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.450 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3n63 | XFN | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 3stx | BKA | Methylketone synthase I | / | 0.450 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.450 | |
| 4ofu | DHT | Androgen receptor | / | 0.450 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1qw5 | 14W | Nitric oxide synthase, inducible | 1.14.13.39 | 0.449 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.449 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.449 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3frk | TQP | QdtB | / | 0.449 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.449 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.449 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.448 | |
| 2vcw | ZZA | Hematopoietic prostaglandin D synthase | / | 0.448 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.448 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.448 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.448 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3n61 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 3ov4 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.448 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.448 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.448 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.448 | |
| 4ys0 | ADP | Protein translocase subunit SecA | / | 0.448 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.448 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.447 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.447 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.447 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.447 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.447 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.447 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.447 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.447 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.447 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.447 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.446 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.446 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.446 | |
| 3oq6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.446 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.445 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.445 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.445 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3up3 | XCA | aceDAF-12 | / | 0.445 | |
| 3zln | H0Y | Bcl-2-like protein 1 | / | 0.445 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.445 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.445 | |
| 1e3k | R18 | Progesterone receptor | / | 0.444 | |
| 1err | RAL | Estrogen receptor | / | 0.444 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.444 | |
| 1osv | CHC | Bile acid receptor | / | 0.444 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.444 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.444 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.444 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.444 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.444 | |
| 2xvw | 9NR | Serum albumin | / | 0.444 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.444 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.444 | |
| 3lu8 | IQX | Serum albumin | / | 0.444 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.444 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.444 | |
| 1eq2 | ADQ | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.443 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.443 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.443 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3fqk | 79Z | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3gan | SVR | Protein RDM1 | / | 0.443 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.443 | |
| 4hx5 | 19V | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.443 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.443 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.442 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.442 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.442 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2qjp | SMA | Cytochrome b | / | 0.442 | |
| 2rs1 | W84 | Genome polyprotein | / | 0.442 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2ynh | EUR | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 3abx | RCB | Glucanase | / | 0.442 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.442 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.442 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 4pd6 | URI | Nucleoside permease | / | 0.442 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.441 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.441 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.441 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.441 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.441 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.441 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 3wiz | LC6 | Bcl-2-like protein 1 | / | 0.441 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.441 | |
| 3zqt | TES | Androgen receptor | / | 0.441 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.441 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.441 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.441 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.440 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.440 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.440 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.440 | |
| 1l0l | FMX | Cytochrome b | / | 0.440 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1swt | BTN | Streptavidin | / | 0.440 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2kce | D16 | Thymidylate synthase | / | 0.440 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 2w8y | NDR | Progesterone receptor | / | 0.440 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 3eej | 53R | Uncharacterized protein | / | 0.440 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.440 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3n5y | XFL | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.440 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.440 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.440 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5l7d | CLR | Smoothened homolog | / | 0.440 |