Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3g1l | RF2 | HTH-type transcriptional regulator EthR |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3g1l | RF2 | HTH-type transcriptional regulator EthR | / | 1.000 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.714 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.666 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.616 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.605 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.602 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.601 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.577 | |
| 3p0g | P0G | Beta-2 adrenergic receptor | / | 0.512 | |
| 4n1f | CZH | Obelin | / | 0.507 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.494 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.494 | |
| 3ny9 | JSZ | Beta-2 adrenergic receptor | / | 0.494 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.491 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.491 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.489 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.489 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.487 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.486 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.485 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.485 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.485 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.484 | |
| 1uhh | CZP | Aequorin-2 | / | 0.483 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.483 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.483 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.482 | |
| 1jf0 | CZH | Obelin | / | 0.482 | |
| 1qv1 | CZH | Obelin | / | 0.482 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.482 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.482 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.480 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.479 | |
| 5dp2 | NAP | CurF | / | 0.479 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.478 | |
| 4phl | PIL | Phosphodiesterase | / | 0.478 | |
| 4was | COO | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.478 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.477 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.477 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.477 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.476 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.476 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.476 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.475 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.475 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.475 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.475 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.474 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.474 | |
| 1uhj | CZB | Aequorin-2 | / | 0.473 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.473 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.473 | |
| 3ndj | JHZ | Methyltransferase | / | 0.472 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.471 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.471 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.470 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.470 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.470 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.470 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.470 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.469 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.469 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.469 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.468 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.467 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.466 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.466 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.466 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.466 | |
| 4ggz | BTN | Bll1558 protein | / | 0.466 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.466 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.466 | |
| 2rr1 | W8R | Genome polyprotein | / | 0.465 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.465 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.464 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.464 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.463 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.463 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.463 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.463 | |
| 1dtp | APU | Diphtheria toxin | / | 0.462 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.462 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.462 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.462 | |
| 3w8z | HTK | Putative FAD-dependent oxygenase EncM | / | 0.462 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.461 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.461 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.461 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.461 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.461 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 2r8o | T5X | Transketolase 1 | / | 0.460 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.460 | |
| 4l9q | 9TP | Serum albumin | / | 0.460 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.460 | |
| 4x7y | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.460 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.460 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2r8p | T6F | Transketolase 1 | / | 0.459 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.459 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.458 | |
| 1jje | BYS | Beta-lactamase | / | 0.458 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.458 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.458 | |
| 3c1o | NAP | Eugenol synthase | / | 0.458 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.458 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.458 | |
| 4hx5 | 19V | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.458 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3lu8 | IQX | Serum albumin | / | 0.457 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.457 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.457 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.456 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.456 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.456 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.455 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.455 | |
| 3dr4 | G4M | GDP-perosamine synthase | / | 0.455 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.455 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.455 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.455 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.455 | |
| 1xud | PB4 | Collagenase 3 | 3.4.24 | 0.454 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.454 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.454 | |
| 2rs1 | W84 | Genome polyprotein | / | 0.454 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.454 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.454 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.453 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2r04 | W71 | Genome polyprotein | / | 0.453 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 3abx | RCB | Glucanase | / | 0.453 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.453 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.453 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.452 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.452 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.452 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.452 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.452 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.451 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3reo | SAH | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.451 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.451 | |
| 4nv7 | COA | Arylamine N-acetyltransferase | / | 0.451 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.450 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.450 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.450 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.450 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.450 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.450 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.449 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.449 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2oat | PFM | Ornithine aminotransferase, mitochondrial | 2.6.1.13 | 0.449 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.449 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.449 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.449 | |
| 4j7h | TRH | PCZA361.3 | / | 0.449 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.449 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.449 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.448 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.448 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 3b1p | NOS | PfkB carbohydrate kinase family protein | / | 0.448 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3ies | M24 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.448 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.448 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.448 | |
| 4iah | 1DX | Alr2278 protein | / | 0.448 | |
| 4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.448 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.447 | |
| 2cul | FAD | GidA-related protein | / | 0.447 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.447 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.447 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 5doz | NDP | JamJ | / | 0.447 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.447 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.446 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.446 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3oht | 1N1 | Mitogen-activated protein kinase | / | 0.446 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 3tfy | MET_LEU_GLY_PRO | N-alpha-acetyltransferase 50 | 2.3.1 | 0.446 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.446 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.446 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.446 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 5f8u | P32 | Beta-1 adrenergic receptor | / | 0.446 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.445 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.445 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.445 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.445 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.445 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.445 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4ynp | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.445 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.445 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.445 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.444 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.444 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.444 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.444 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.444 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.444 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.444 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.444 | |
| 4e2x | TYD | Methyltransferase | / | 0.444 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4rel | KMP | Glycosyltransferase | / | 0.444 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.444 | |
| 1ciz | DPS | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.443 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.443 | |
| 1osv | CHC | Bile acid receptor | / | 0.443 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1qv0 | CZH | Obelin | / | 0.443 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.443 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.443 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.443 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.443 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.443 | |
| 4afh | L0B | Achbp | / | 0.443 | |
| 4iae | 1DX | Alr2278 protein | / | 0.443 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.443 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.443 | |
| 1h5n | PGD | Dimethyl sulfoxide/trimethylamine N-oxide reductase | 1.7.2.3 | 0.442 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.442 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2x96 | RX3 | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.442 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.442 | |
| 2zw5 | COA | Bleomycin acetyltransferase | / | 0.442 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3e8s | SAH | Uncharacterized protein | / | 0.442 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.442 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.441 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 1i7l | ATP | Synapsin-2 | / | 0.441 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.441 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.441 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.441 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
| 2qu5 | 276 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3dz2 | A8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.441 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.441 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.441 | |
| 3two | NDP | Mannitol dehydrogenase | / | 0.441 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.441 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.441 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 5a8e | XTK | Beta-1 adrenergic receptor | / | 0.441 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.440 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.440 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.440 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.440 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.440 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.440 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.440 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.440 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.440 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4xvy | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.440 |