sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 1.000 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.653 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.642 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.642 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.641 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.637 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.635 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.634 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.631 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.628 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.623 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.623 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.622 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.622 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.621 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.621 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.620 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.619 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.618 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.616 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.614 | |
| 3k2b | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.611 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.608 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.607 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.606 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.606 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.602 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.600 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.598 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.594 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.593 | |
| 1jn0 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.590 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.589 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.586 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.586 | |
| 3l0d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.583 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.583 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.580 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.578 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.577 | |
| 1rm3 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.569 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.569 | |
| 2d2i | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.568 | |
| 3l4s | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.561 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.559 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.558 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.555 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.554 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.552 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.552 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.552 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.548 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.547 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.542 | |
| 1cer | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.541 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.541 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.539 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.504 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.502 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.497 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.481 | |
| 2y3s | TIR | TamL | / | 0.480 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.479 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.478 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.475 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.475 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.475 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.475 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.475 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.474 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.473 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.473 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.472 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.471 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.471 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.471 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.471 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.470 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.470 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.469 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.469 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.469 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.466 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.466 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.466 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.466 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.466 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.466 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.466 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.465 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.465 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.465 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.464 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.464 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.463 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.462 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.462 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3zuy | TCH | Transporter | / | 0.461 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.461 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.460 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.460 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.459 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.459 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.459 | |
| 4f07 | FAD | Styrene monooxygenase component 2 | / | 0.459 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.459 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.457 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.457 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.457 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.457 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.456 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.456 | |
| 4jxr | ACO | Acetyltransferase | / | 0.456 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.455 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2b60 | RIT | Pol polyprotein | / | 0.455 | |
| 2pwr | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.455 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.455 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3gob | HXX | DdmC | / | 0.455 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 1qbr | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.454 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.454 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.454 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.453 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.453 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.453 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.453 | |
| 3qof | GDP | Atlastin-1 | 3.6.5 | 0.453 | |
| 3sa3 | 23X | Protease | / | 0.453 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.453 | |
| 4dja | FAD | (6-4) photolyase | / | 0.453 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.453 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.453 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.453 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.453 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.452 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.452 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3nxe | 2NC | Protease | / | 0.452 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.452 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.452 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.451 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.451 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.451 | |
| 2hs2 | 017 | Protease | / | 0.451 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.451 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.450 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.450 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.450 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.450 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.450 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.450 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3vfb | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4a28 | ADP | Kinesin-like protein KIF11 | / | 0.450 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2oxt | SAM | Genome polyprotein | / | 0.449 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.449 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.449 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3ec0 | GRL | Gag-Pol polyprotein | 3.4.23.47 | 0.449 | |
| 3o9a | K14 | Pol polyprotein | / | 0.449 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.449 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.449 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.449 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.449 | |
| 1c6x | 3IN | Protease | / | 0.448 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.448 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.448 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.448 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2hc0 | AB2 | Protease | / | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.448 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.448 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.448 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 3u9e | COA | Lmo1369 protein | / | 0.448 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.448 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1meu | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.447 | |
| 1pro | A88 | Gag-Pol polyprotein | / | 0.447 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2idw | 017 | Protease | / | 0.447 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.447 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.447 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 3o9c | K20 | Pol polyprotein | / | 0.447 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 4djo | MK5 | Pol polyprotein | / | 0.447 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.446 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.446 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.446 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.446 | |
| 3vf7 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.446 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.446 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.446 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.446 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.446 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.445 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.445 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.445 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.445 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.445 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.445 | |
| 2p3a | 3TL | Pol protein | / | 0.445 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.445 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4dqh | 017 | Gag-Pol polyprotein | / | 0.445 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.445 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.445 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 1d4l | PI9 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1fml | RTL | Retinol dehydratase | / | 0.444 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.444 | |
| 2qi1 | MZ4 | Gag-Pol polyprotein | / | 0.444 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.444 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.444 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.444 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 3w16 | P9J | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.444 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.444 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4njs | G08 | Protease | / | 0.444 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.444 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1g2k | NM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1hk2 | T44 | Serum albumin | / | 0.443 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.443 | |
| 1met | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.443 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.443 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3gga | GGW | Gag-Pol polyprotein | / | 0.443 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.443 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.443 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.443 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.443 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.443 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.443 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.443 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.442 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.442 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.442 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.442 | |
| 2q3k | MUW | Gag-Pol polyprotein | / | 0.442 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.442 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.442 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3ekq | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3gi4 | K60 | Gag-Pol polyprotein | / | 0.442 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.442 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.442 | |
| 3qc9 | ADP | Rhodopsin kinase | / | 0.442 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.442 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.442 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.441 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.441 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1gqt | ACP | Ribokinase | / | 0.441 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.441 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.441 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.441 | |
| 3jvy | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.441 | |
| 3s54 | 017 | Protease | / | 0.441 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.441 | |
| 4apu | A2K | Progesterone receptor | / | 0.441 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.441 | |
| 5dbv | COA | Aldehyde Dehydrogenase | / | 0.441 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1fej | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.440 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1vij | BAY | Gag-Pol polyprotein | / | 0.440 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.440 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.440 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.440 | |
| 3d20 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.440 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.440 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3sa7 | 55A | Protease | / | 0.440 | |
| 3sa9 | A68 | Protease | / | 0.440 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.440 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.440 |