sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1txt | CAA | HMG-CoA synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1txt | CAA | HMG-CoA synthase | / | 1.000 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.602 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.593 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.588 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.564 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.559 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.552 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.533 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.491 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.490 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.489 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.487 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 3zuy | TCH | Transporter | / | 0.487 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.486 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.484 | |
| 1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.482 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.482 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.480 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.479 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.478 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.477 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.477 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.474 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.474 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.473 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.472 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.472 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.472 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.468 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.467 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.467 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.466 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.465 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.465 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.465 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.464 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.464 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.464 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.463 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.463 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.463 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.462 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 1c7o | PPG | Hemolysin | / | 0.461 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.461 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.461 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.460 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.460 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.459 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.459 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.459 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.459 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.458 | |
| 1ppj | ANY | Cytochrome b | / | 0.458 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.458 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.458 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1zdw | FLV | Prenyltransferase | / | 0.457 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.457 | |
| 4l9k | EHF | Serum albumin | / | 0.457 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.456 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.456 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.456 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.456 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.456 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.456 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.455 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.455 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.455 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.454 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 2e1z | B4P | Propionate kinase | / | 0.454 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.454 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.453 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.453 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.453 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.453 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.453 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.452 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.451 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.451 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.451 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4die | C5P | Cytidylate kinase | / | 0.451 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 5dp2 | NAP | CurF | / | 0.451 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.450 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.450 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.450 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.450 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.450 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.450 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.450 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.449 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.449 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.449 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.449 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.449 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.449 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.449 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.448 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3r96 | ACO | MccE protein | / | 0.448 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.448 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.448 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.447 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.447 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.447 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.447 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.447 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.447 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.447 | |
| 3up0 | D7S | aceDAF-12 | / | 0.447 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.447 | |
| 3wbw | NDP | Putative 2,5-diketo-D-gluconic acid reductase | / | 0.447 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.446 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.446 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.446 | |
| 4irn | FAD | AnaB | / | 0.446 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.445 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.445 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.445 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.445 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.445 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.445 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.445 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.444 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.444 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.444 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.444 | |
| 4kwh | NAP | Reductase homolog | / | 0.444 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.443 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.443 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.443 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.443 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.443 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.443 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.443 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.443 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.443 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.443 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.443 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.442 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.442 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.442 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.442 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.442 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.441 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.441 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.441 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.441 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.440 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.440 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2o12 | FMN | Chorismate synthase | / | 0.440 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.440 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3vth | APC | Carbamoyltransferase | / | 0.440 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.440 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.440 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.440 |