sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.693 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.661 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.630 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.629 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.620 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.607 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.602 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.582 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.555 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.550 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.546 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.535 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.534 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.533 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.529 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.526 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.525 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.523 | |
| 3qly | 55V | Uncharacterized protein | / | 0.519 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.515 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3dmj | GWE | Pol protein | / | 0.510 | |
| 3eek | 53S | Uncharacterized protein | / | 0.510 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.508 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.508 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.508 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.501 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.500 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.498 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.497 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.497 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.496 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.496 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.496 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.495 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.494 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.493 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.492 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.492 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.490 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.489 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.489 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.489 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.489 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.489 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.489 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.488 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.488 | |
| 3cse | N22 | Uncharacterized protein | / | 0.487 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.486 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.485 | |
| 1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.485 | |
| 2jfa | RAL | Estrogen receptor | / | 0.485 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.485 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.485 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.483 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.483 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.483 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.483 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.482 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.482 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.482 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.481 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.481 | |
| 3bej | MUF | Bile acid receptor | / | 0.481 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.481 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.480 | |
| 3dol | GWI | Pol protein | / | 0.480 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.480 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.479 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.478 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.478 | |
| 3eem | 53V | Uncharacterized protein | / | 0.478 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.478 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.477 | |
| 3e6o | A55 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.477 | |
| 4boe | CLR | Japanin | / | 0.477 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1l2i | ETC | Estrogen receptor | / | 0.476 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.476 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.476 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.476 | |
| 3eel | 53T | Uncharacterized protein | / | 0.475 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.475 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.475 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.474 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.474 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.474 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.473 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.473 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.473 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.473 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.473 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.473 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.472 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.472 | |
| 1rt1 | MKC | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.471 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.471 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.471 | |
| 4au7 | SAH | Histone-lysine N-methyltransferase KMT5C | 2.1.1.43 | 0.471 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 1rt2 | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.470 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.470 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.470 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.470 | |
| 4eux | HW1 | Nitric oxide synthase, brain | 1.14.13.39 | 0.470 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.469 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.469 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.469 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.467 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.467 | |
| 1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.467 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.467 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.467 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.467 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.467 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.466 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.466 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.466 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.466 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.466 | |
| 4g1q | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.466 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.465 | |
| 1yin | CM3 | Estrogen receptor | / | 0.465 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.465 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.465 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.465 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.464 | |
| 3eej | 53R | Uncharacterized protein | / | 0.464 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.464 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.464 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.464 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.464 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.464 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.463 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2iog | IOG | Estrogen receptor | / | 0.462 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.462 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 4lb2 | DM5 | Serum albumin | / | 0.462 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.462 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1gnw | GTX | Glutathione S-transferase F2 | 2.5.1.18 | 0.461 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.461 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.461 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.460 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.460 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 3l71 | AZO | Cytochrome b | / | 0.460 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.460 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.460 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.460 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4l8u | 9AZ | Serum albumin | / | 0.460 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.459 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1zky | 689 | Estrogen receptor | / | 0.459 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.459 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.459 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.459 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.458 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.458 | |
| 2rki | TT1 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.458 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 1eio | GCH | Gastrotropin | / | 0.457 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.457 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.457 | |
| 4bqu | CLR | Japanin | / | 0.457 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.456 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.456 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.456 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.456 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.456 | |
| 3up3 | XCA | aceDAF-12 | / | 0.456 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.456 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.456 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.455 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.455 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.455 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.455 | |
| 3zux | TCH | Transporter | / | 0.455 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.454 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3h1j | SMA | Cytochrome b | / | 0.454 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.454 | |
| 3lu8 | IQX | Serum albumin | / | 0.454 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.454 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.454 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.454 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.454 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.454 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.454 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.453 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.453 | |
| 3dok | GWJ | Pol protein | / | 0.453 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4b12 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.453 | |
| 4fw0 | 5KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.453 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.453 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.452 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.452 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.452 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.452 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.452 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.452 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.452 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.452 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.451 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.451 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.451 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.451 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.450 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.450 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.450 | |
| 1ysx | 4EB | Serum albumin | / | 0.450 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.450 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.450 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.450 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.450 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.450 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.450 | |
| 1c1c | 612 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1gwr | EST | Estrogen receptor | / | 0.449 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.449 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.449 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.449 | |
| 2wpx | ACO | Orf14 | / | 0.449 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.449 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.449 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.448 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.448 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.448 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3drp | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 3n62 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3tam | M06 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.448 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.448 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.448 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.447 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.447 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.447 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.447 | |
| 2ocf | EST | Estrogen receptor | / | 0.447 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.447 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.447 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.447 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1s1t | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.446 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.446 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.446 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.446 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.446 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.446 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.446 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.446 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.446 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.446 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.446 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.446 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.445 | |
| 2p15 | EZT | Estrogen receptor | / | 0.445 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.445 | |
| 3cx5 | SMA | Cytochrome b | / | 0.445 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.445 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.445 | |
| 3oll | EST | Estrogen receptor beta | / | 0.445 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4c68 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4gqe | 6KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.445 | |
| 4l9q | 9TP | Serum albumin | / | 0.445 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.445 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.444 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.444 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.444 | |
| 3n65 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3rqm | X2E | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3tgu | WF3 | Cytochrome b | / | 0.444 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.444 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.444 | |
| 4iji | 99T | Glutathione S-transferase-like protein YibF | / | 0.444 | |
| 4m7v | RAR | Dihydrofolate reductase | / | 0.444 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.444 | |
| 5dxg | EST | Estrogen receptor | / | 0.444 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.444 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.443 | |
| 1krv | 147 | Galactoside O-acetyltransferase | 2.3.1.18 | 0.443 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.443 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.443 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.443 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.443 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.443 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.443 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.443 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.443 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.443 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2ele | SAH | Diphthine synthase | / | 0.442 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.442 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.442 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.442 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.442 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.441 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.441 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 3aba | FLI | Cytochrome P450 | / | 0.441 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.441 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.441 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.441 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.441 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4id5 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 5ag5 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.440 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.440 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.440 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.440 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.440 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.440 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.440 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.440 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.440 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.440 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.440 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.440 |