Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.293 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.962 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.947 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.941 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.936 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.923 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.901 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.892 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.873 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.859 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.843 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.838 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.831 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.825 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.820 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.801 | |
| 4nev | FAD | Trypanothione reductase | / | 0.797 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.791 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.782 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.773 | |
| 4jn9 | FAD | DepH | / | 0.771 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.769 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.765 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.761 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.759 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.752 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.750 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.750 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.745 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.745 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.744 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.740 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.738 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.738 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.737 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.735 | |
| 4nte | FAD | DepH | / | 0.734 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.733 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.731 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.729 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.728 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.725 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.725 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.724 | |
| 2wow | FAD | Trypanothione reductase | / | 0.722 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.721 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.721 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.718 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.717 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.717 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.716 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.716 | |
| 4k5r | FAD | Oxygenase | / | 0.716 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.715 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.715 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.715 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.715 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.713 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.713 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.709 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.709 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.708 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.708 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.708 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.707 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.706 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.706 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.705 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.704 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.704 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.703 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.703 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.703 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.702 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.702 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.702 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.701 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.700 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.699 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.699 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.699 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.699 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.699 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.698 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.697 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.697 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.697 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.695 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.695 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.695 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.694 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.693 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.693 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.693 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.692 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.691 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.691 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.691 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.690 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.690 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.690 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.690 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.690 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.689 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.689 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.689 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.688 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.688 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.688 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.687 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.687 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.686 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.686 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.686 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.686 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.685 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.684 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.684 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.684 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.683 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.683 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.683 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.682 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.682 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.682 | |
| 4rje | FNR | Lactate oxidase | / | 0.682 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.681 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.681 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.681 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.681 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.680 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.680 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.680 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.680 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.678 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.678 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.677 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.677 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.677 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.677 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.676 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.676 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.676 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.676 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.675 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.675 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.674 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.674 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.674 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.673 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.672 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.672 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.672 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.672 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.672 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.671 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.671 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.671 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.671 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.670 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.670 | |
| 1n9n | FMN | Putative blue light receptor | / | 0.670 | |
| 2cdu | FAD | NADH oxidase | / | 0.670 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.670 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.670 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.670 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.670 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.670 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.669 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.669 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.669 | |
| 4utm | FNR | Xenobiotic reductase | / | 0.669 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.669 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.668 | |
| 2v0u | FMN | NPH1-1 | / | 0.668 | |
| 2v1a | FMN | NPH1-1 | / | 0.668 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.668 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.668 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.668 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.667 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.667 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.667 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.667 | |
| 2bab | FAD | Putative aminooxidase | / | 0.666 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.666 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.666 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.666 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.665 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.665 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.665 | |
| 1ea0 | FMN | Glutamate synthase [NADPH] large chain | 1.4.1.13 | 0.664 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.664 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.664 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.664 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.663 | |
| 2isj | FMN | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.663 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.663 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.663 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.662 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.662 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.661 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.661 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.661 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.661 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.661 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.661 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.661 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.661 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.660 | |
| 4kuk | RBF | Putative blue-light photoreceptor | / | 0.660 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.659 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.659 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.659 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.658 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.658 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.658 | |
| 4hj4 | FMN | LOV protein | / | 0.658 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.657 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.657 | |
| 4tm4 | FDA | KtzI | / | 0.657 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.655 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.655 | |
| 2qa1 | FAD | PgaE | / | 0.655 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.654 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.654 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.654 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.653 | |
| 3n39 | FMN | Protein NrdI | / | 0.653 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.653 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.653 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.653 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.652 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.652 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.652 | |
| 1p4m | FMN | Riboflavin kinase | 2.7.1.26 | 0.651 | |
| 1t6y | FMN | Riboflavin biosynthesis protein | / | 0.651 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.651 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.651 | |
| 3rha | FDA | Putrescine oxidase | / | 0.651 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.650 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.650 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.650 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.650 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.650 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.650 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.650 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.650 |