sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rqz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4rqz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 1.000 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.516 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.506 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.503 | |
| 5ii2 | LU2 | Protein polybromo-1 | / | 0.503 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.491 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.489 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.488 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.488 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.486 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.485 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.482 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.482 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.481 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.480 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.480 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.477 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.477 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.477 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.477 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.476 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.476 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.474 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.474 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.474 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.474 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.473 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.472 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.471 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.471 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.471 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 1eio | GCH | Gastrotropin | / | 0.470 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.470 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.469 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.469 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.468 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.468 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.468 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.467 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.466 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.466 | |
| 2p2x | SAH | Diphthine synthase | / | 0.466 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.466 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.465 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.465 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.465 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.464 | |
| 2eau | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.464 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.464 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.464 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.464 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.463 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.463 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.463 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.462 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.462 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.462 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.462 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.461 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.461 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4l8u | 9AZ | Serum albumin | / | 0.461 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.460 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.460 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.460 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.460 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.460 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.459 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.459 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.459 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.458 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.458 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.458 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.458 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.458 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.458 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.458 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.458 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.458 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.457 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.456 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.456 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.456 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.455 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.455 | |
| 2y3r | TIR | TamL | / | 0.455 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.455 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.455 | |
| 3zux | TCH | Transporter | / | 0.455 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.455 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.455 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.455 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.455 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.455 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.454 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.454 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.454 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.454 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.453 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.453 | |
| 4ocg | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.453 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.452 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.452 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.452 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.452 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.452 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.452 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.452 | |
| 3zuy | TCH | Transporter | / | 0.452 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.452 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.452 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.452 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 3kdt | 7HA | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.451 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.451 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 1osv | CHC | Bile acid receptor | / | 0.450 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.450 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.450 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.450 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.449 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.449 | |
| 3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3r3d | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.449 | |
| 3vey | 0H5 | Glucokinase | 2.7.1.2 | 0.449 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.449 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.449 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.449 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.449 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 1ppj | SMA | Cytochrome b | / | 0.448 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.448 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.448 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.448 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.447 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.447 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.447 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.447 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.447 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.447 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.447 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.446 | |
| 2e2q | ADP | ATP-dependent hexokinase | / | 0.446 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.446 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.446 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.445 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.445 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.445 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.445 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3h18 | PMS | Esterase/lipase | / | 0.445 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.445 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1sn5 | T3 | Transthyretin | / | 0.444 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.444 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.444 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.444 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.444 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.444 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.444 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.444 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.444 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.443 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.443 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.443 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.443 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.443 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.443 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.443 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.443 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2bx8 | AZQ | Serum albumin | / | 0.442 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.442 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.442 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.442 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.442 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.442 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.442 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4j55 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.442 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 1err | RAL | Estrogen receptor | / | 0.441 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.441 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2fb2 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.441 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.441 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.441 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.441 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.441 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.441 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.441 | |
| 3wti | CT4 | Acetylcholine-binding protein | / | 0.441 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.441 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.440 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2cbs | R13 | Cellular retinoic acid-binding protein 2 | / | 0.440 | |
| 2e08 | SAH | Diphthine synthase | / | 0.440 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2p5c | SAH | Diphthine synthase | / | 0.440 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3zdg | XRX | Acetylcholine-binding protein | / | 0.440 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.440 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.440 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.440 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 |