sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 1.000 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.569 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.489 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.488 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.484 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.484 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.483 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.481 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.481 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.480 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.477 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.476 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.476 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.476 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.476 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.475 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.474 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.473 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.471 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.468 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.468 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.468 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.468 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.467 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.467 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.466 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.466 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.466 | |
| 3zuy | TCH | Transporter | / | 0.466 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.466 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.465 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 2bxm | IMN | Serum albumin | / | 0.464 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.464 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.464 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.464 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.464 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.462 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.462 | |
| 3gob | HXX | DdmC | / | 0.462 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.462 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.462 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.462 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.461 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.460 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.460 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.460 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.460 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.459 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.459 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.459 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.459 | |
| 5a3c | NAD | SIR2 family protein | / | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.458 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.458 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.458 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.458 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.457 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.457 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.457 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.456 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.456 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.456 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.455 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.455 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.455 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.455 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.455 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.455 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.454 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1c70 | L75 | Protease | / | 0.453 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.453 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.453 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.453 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.452 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.452 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.452 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.452 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.452 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1r2j | FAD | FkbI | / | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.451 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.451 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.451 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.450 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.450 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.450 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.450 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.450 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.450 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.449 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.449 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.449 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.449 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.448 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.448 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.448 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.448 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.448 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.447 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.447 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.447 | |
| 2y3s | TIR | TamL | / | 0.447 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.447 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.447 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.447 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.447 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.447 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.447 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.446 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.446 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.446 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.446 | |
| 3u9e | COA | Lmo1369 protein | / | 0.446 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.446 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.445 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.445 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.445 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.445 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.445 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3zia | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.445 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.445 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.444 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.444 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4dja | FAD | (6-4) photolyase | / | 0.444 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.444 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.444 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2y4g | TIR | TamL | / | 0.443 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.443 | |
| 4e2b | FMN | Dehydrogenase | / | 0.443 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.443 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.443 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.443 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.442 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.442 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.442 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.442 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.442 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.441 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2acw | UPG | Glycosyltransferase | / | 0.441 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.441 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3dag | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.441 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 5a3b | APR | SIR2 family protein | / | 0.441 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.440 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.440 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.440 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.440 | |
| 2y3r | TRK | TamL | / | 0.440 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.440 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4kwh | NAP | Reductase homolog | / | 0.440 | |
| 4l8u | 9AZ | Serum albumin | / | 0.440 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.440 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 |