sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 1.000 | |
| 3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.728 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.702 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.697 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.678 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.672 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.669 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.663 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.662 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.659 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.659 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.649 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.649 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.648 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.642 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.641 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.641 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.638 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.638 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.634 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.631 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.630 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.628 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.626 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.626 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.625 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.625 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.623 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.622 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.617 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.612 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.612 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.611 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.609 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.608 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.606 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.603 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.603 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.601 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.600 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.597 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.596 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.594 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.593 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.586 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.583 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.577 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.568 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.560 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.555 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.554 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.550 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.543 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.534 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.524 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.518 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.505 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.503 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.503 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.496 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.496 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.494 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.494 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.494 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.487 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.486 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.486 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.485 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.485 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.484 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.483 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.483 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.483 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.482 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.481 | |
| 1s36 | CEI | Obelin | / | 0.480 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.480 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.479 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.479 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.479 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.478 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.477 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.475 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.473 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.472 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.472 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.472 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.471 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.471 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.467 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.467 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.467 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.467 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.466 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.466 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 3up3 | XCA | aceDAF-12 | / | 0.465 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.464 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.464 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.464 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.463 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.463 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.462 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.462 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.462 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.461 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.461 | |
| 4kmz | FOL | Folate receptor beta | / | 0.461 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.460 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.460 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.459 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.459 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4lrh | FOL | Folate receptor alpha | / | 0.459 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.459 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.458 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.458 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.458 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.457 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.456 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.456 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.456 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.456 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.456 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.456 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.455 | |
| 1x98 | NAP | Aldose reductase | 1.1.1.21 | 0.455 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.455 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.454 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.454 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.454 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.453 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.453 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.453 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.453 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.453 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.453 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.453 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 1gm8 | SOX | Penicillin G acylase | 3.5.1.11 | 0.452 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.452 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.452 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.452 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.451 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.451 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.451 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 4xp1 | LDP | Sodium-dependent dopamine transporter | / | 0.451 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.450 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.450 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.450 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.449 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2vq3 | NAP | Metalloreductase STEAP3 | / | 0.449 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.449 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.449 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.449 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.448 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3pn1 | IVH | DNA ligase | / | 0.448 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.448 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.447 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.447 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.447 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.447 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 1rxj | BNI | Streptavidin | / | 0.446 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.446 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.446 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.446 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.445 | |
| 1qv0 | CZH | Obelin | / | 0.445 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.445 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.445 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4phl | PIL | Phosphodiesterase | / | 0.445 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.444 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.444 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.444 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.443 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.443 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.443 | |
| 4a33 | PS8 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.442 | |
| 1el4 | CTZ | Obelin | / | 0.442 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.442 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.442 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.442 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.441 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.441 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.441 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.441 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.441 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.441 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.441 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.441 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.441 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.440 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.440 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 3x03 | ANP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.440 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.440 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.440 |