sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ibq | ATP | Pyridoxal kinase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ibq | ATP | Pyridoxal kinase | / | 1.000 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.554 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.528 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.524 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.509 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.491 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.491 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.490 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.487 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.486 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.486 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.486 | |
| 3u9e | COA | Lmo1369 protein | / | 0.485 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.481 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.481 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.480 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.477 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.476 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.475 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.473 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.472 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.472 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.471 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.471 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.471 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.470 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.470 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.469 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.469 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.467 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.467 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.466 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.466 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.465 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.465 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.464 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.464 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.462 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.461 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.461 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.460 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.459 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.459 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.459 | |
| 2oo5 | TXD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.459 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 3qai | XNN | Ketohexokinase | / | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.458 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.458 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.457 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.457 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.456 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.456 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.456 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.456 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.456 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.456 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.455 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.455 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.455 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.455 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.455 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.455 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.454 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.454 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.454 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.454 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.454 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.454 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.454 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.453 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.453 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.453 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.452 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.452 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 5cyo | GDP | Septin-9 | / | 0.452 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.451 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.451 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.451 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.451 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.451 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.450 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.450 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.450 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.450 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.450 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.449 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.449 | |
| 3vth | APC | Carbamoyltransferase | / | 0.449 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.449 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.448 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.448 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.448 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.448 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.448 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.447 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.447 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.447 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3zuy | TCH | Transporter | / | 0.447 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.447 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.447 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3nbv | ANP | Ketohexokinase | / | 0.446 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 2xgo | ZKD | Uncharacterized protein | / | 0.445 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 3q1k | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.445 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.445 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.444 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.444 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.444 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.444 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.444 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.444 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.444 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1ej2 | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.443 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.443 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.443 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.443 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.443 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.443 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.443 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.443 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.443 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.442 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3eld | SFG | Methyltransferase | / | 0.442 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.442 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.441 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.441 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.441 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.441 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.441 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.441 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.440 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.440 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.440 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 | |
| 4u7w | NDP | MxaA | / | 0.440 | |
| 4yqf | GDP | Septin-9 | / | 0.440 |